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Alterations to Cerebral Perfusion, Metabolite Profiles, and Neuronal Morphology in the Hippocampus and Cortex of Male and Female Mice during Chronic Exposure to a High-Salt Diet

Excess dietary salt reduces resting cerebral blood flow (CBF) and vascular reactivity, which can limit the fueling of neuronal metabolism. It is hitherto unknown whether metabolic derangements induced by high-salt-diet (HSD) exposure during adulthood are reversed by reducing salt intake. In this study, male and female mice were fed an HSD from 9 to 16 months of age, followed by a normal-salt diet

Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease

Background: In Alzheimer’s disease (AD), fibrillar tau initially occurs locally and progresses preferentially between closely connected regions. However, the underlying sources of regional vulnerability to tau pathology remain unclear. Previous brain-autopsy findings suggest that the myelin levels—which differ substantially between white matter tracts in the brain—are a key modulating factor of re

Time dependence of heterogeneous ice nucleation by ambient aerosols : laboratory observations and a formulation for models

The time dependence of ice-nucleating particle (INP) activity is known to exist, yet for simplicity it is often omitted in atmospheric models as an approximation. Hitherto, only limited experimental work has been done to quantify this time dependency, for which published data are especially scarce regarding ambient aerosol samples and longer timescales. In this study, the time dependence of INP ac

Characteristics of SARS-CoV-2-containing aerosols in hospital corridors

The aim of this work is to investigate the presence of airborne SARS-CoV-2 in corridors of infection wards, and gain more detailed size information of SARS-CoV-2-containing aerosols. Associations between SARS-CoV-2 presence and relative humidity and/or temperature in the facilities is also explored.

Law, Society, and Corruption: Exploring (Anti-) Corruption From Interdisciplinary and Multilevel Perspectives

Corruption has become, without a doubt, a buzzword in both academic and policy debates over the last three decades. The initial view that “corruption greases the wheels of economic growth” in the newly independent states of Africa and Asia has lost its validity in light of the current and ever-growing global coalition against corruption, spearheaded by Transparency International (TI) and the World

Urban Sustainability : Recovering and Utilizing Urban Excess Heat

Urban heat sources from urban infrastructure and buildings could meet ~10% of the European building heating demand. There is, however, limited information on how to use them. The EU project ReUseHeat has generated much of the existing knowledge on urban waste heat recovery implementation. Heat recovery from a data center, hospital and from water were demonstrated. Additionally, the project generat

Tracking structural solvent reorganization and recombination dynamics following e-photoabstraction from aqueous I-with femtosecond x-ray spectroscopy and scattering

We present a sub-picosecond resolved investigation of the structural solvent reorganization and geminate recombination dynamics following 400 nm two-photon excitation and photodetachment of a valence p electron from the aqueous atomic solute, I-(aq). The measurements utilized time-resolved X-ray Absorption Near Edge Structure (TR-XANES) spectroscopy and X-ray Solution Scattering (TR-XSS) at the Li

Planetary Politics in the Twenty-Second Century

After two centuries of immanent planetary politics, by the twenty-second century the politics had become planetary. This means that since the 2020s political analysis encompasses the entire sphere of the planet and cannot be conducted without a holistic approach. The first section remembers the 100-year planetary organic crisis from ecological overshoot in 1970 to population decline in 2070. The r

Sentinel Node Identification with Hybrid Tracer-guided and Conventional Dynamic Sentinel Node Biopsy in Penile Cancer : A Prospective Study in 130 Patients from the Two National Referral Centres in Sweden

BACKGROUND: Studies suggest that a hybrid indocyanine green (ICG)-99mTc-nanocolloid tracer improves sentinel node (SN) identification compared to conventional dynamic sentinel node biopsy (DSNB). OBJECTIVE: To investigate hybrid tracer-guided SN identification in a multicentre setting and determine false-negative (FN) and complication rates. DESIGN, SETTING, AND PARTICIPANTS: A total of 130 patien

Social Enterprises and Tax: Living Apart Together?

This chapter examines the complex relationship between social enterprises and taxation. The focus is not on a specific country, although various examples are mentioned. As specific tax measures for social enterprises are a form of tax incentives, the chapter discusses this public finance concept. In addition, an important legal constraint on introducing such incentives for social enterprises in th

Masking the Past, Legitimizing the Present : State-Making and Precariatization in the Agro-Industrial Landscape, Colombia

History is written by the powerful. Representations of the past are framed within the structures of the dominant institutions today, and other pasts – those of the enslaved, the marginalised, the disenfranchised – are often suppressed. Drawing of Eric Wolf’s Europe and the People Without History, this chapter explores how the fertile lands of the Cauca Valley, Colombia, have been transformed into

PFAS in the Drinking Water Source: Analysis of the Contamination Levels, Origin and Emission Rates

Groundwater contamination caused by the use of the aqueous film-forming foam (AFFF) containing per- and polyfluoroalkyl substances (PFAS) was investigated in southern Sweden. ΣPFAS concentrations in groundwater ranged between 20 and 20,000 ng L−1; PFAS composition was primarily represented by PFOS and PFHxS. The PFAS chain length was suggested to have an impact on the contaminant distribution and

Ghost Installation: Kafferepet

Ghost Installation Kafferepet is one of several "Ghost Installation" compositions in the project. Using small, consumer grade speakers and looping sound collage files, these sound installation compositions are placed in multichannel arrays into the sites they address.Ghost Installation: Kafferepet was installed outside the former site of the Kafferepet konditori (traditional Swedish coffee house),

Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

Concerns have been raised regarding a potentially increased risk of cancer associated with treatment with glucagon-like peptide-1 (GLP-1) receptor agonists. Here, we explored whether fasting and oral glucose tolerance test post-challenge glucose-dependent insulinotropic peptide (GIP) and GLP-1 levels were associated with incident first cancer. Within the cardiovascular re-examination arm of the po