Reproducibility of human epidermal growth factor receptor 2 analysis in primary breast cancer - A national survey performed at pathology departments in Sweden.

Background. HER2 is a treatment predictive factor for the effect of trastuzumab and associated with poor prognosis in breast cancer. The analysis of HER2 must be performed with good quality, with regard to both the immunohistochemical (IHC) and in situ hybridization (ISH) analysis. Material and methods. A tissue microarray (TMA) including 11 breast cancer samples was sent twice (once in 2005 and a

Changes in apoptosis-related pathways in acute myelocytic leukemia.

Expression analysis of apoptotic genes was performed for 15 patients with acute myelocytic leukemia (AML) at the time of diagnosis to identify genes and signaling pathways involved in the regulation of cell survival and apoptosis during leukemogenesis. cDNA array analysis revealed 34 genes whose expression was significantly different compared to others. Tumor suppressor genes TP53 and CDKN2A were

The epistemological role of language use in learning

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Clarity and claims in variation/mutation databasing.

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Replik: Det finns evidens för både metadon och naltrexon

Ludvig Jönsson – Kärleken som överordnat värde

Case studies on software engineering PhD programmes

This report summarizes a PhD study course on Case Studies, Spring 2007. It contains a report on “Checklists for Software Engineering Case Study Research” followed by nine report on minor case studies on different aspects of Software Engineering PhD programmes.

Means of Payment and the Use of Coins in the Viking Age Town of Birka in Sweden. Preliminary Results

Deoxyribonucleic Acid Methylation and Gene Expression of PPARGC1A in Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner.

Context: Low birth weight (LBW) and unhealthy diets are risk factors of metabolic disease including type 2 diabetes (T2D). Genetic, nongenetic, and epigenetic data propose a role of the key metabolic regulator peroxisome proliferator-activated receptor gamma, coactivator 1alpha (PPARGC1A) in the development of T2D. Objective: Our objective was to investigate gene expression and DNA methylation of

Review of "Historieboken"

Variables Associated with Repeated Suicide Attempt in a Criminal Justice Population.

The aim of this study was to identify factors associated with repeated suicide attempts among criminal justice clients examined for substance abuse using the Addiction Severity Index. Among suicide attempters (n = 1,404), repeaters (two or more attempts, n = 770) were compared to nonrepeaters. In logistic regression, repetition was associated with younger age, opioid analgesics, somatic medication

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Treatment of endoleaks: techniques and outcome.

Endoleaks are one of the most common reasons for reinterventions and failure after endovascular aneurysm repair (EVAR). Current classifications divide endoleaks into type I-V but a more pragmatic definition is of direct and indirect endoleaks. Direct endoleaks (type I and III) transmit direct systemic pressure to the aneurysm sac and carry a high risk of aneurysm growth and rupture if left untreat

Mild-induced hypothermia and neuroprognostication following cardiac arrest.

Pricing commodity swaptions in multifactor models

Skuldfrågan viktig vid naturkatastrofer

Understreckare skriven efter tsunamin i Thailand och orkanen Gudrun. Presenterar Jussi Hanska: "Strategies of Sanity and Survival: Religious Responses to Natural Disasters in the Middle Ages", Finnish Literature Society, 220 s, 2002

Different methods to present the effect of blood pressure on cardiovascular diseases by Cox regression.

Studier över Ynglingatal