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Interaction mechanisms of low-level electromagnelic fields in living systems / edited by Bengt Nordön and Claes Romel.

The alteration of release of calcium ions from biological tissue by electromagnetic stimulation has bien reported by several authors (Kaczmarec and Adey 1974:, Bawin et al. 1975, 1978; Bawin and Adey 1976; Blackman et al. 1979, l980a,å; Joines and Blackman 1980, l98l; Joines et al. l98O). Bawin etal. (1975) reported that 147 MHz radiofrequency (RF) electromagnetic radiation altered the release of The 'ion cyclotron resonance hypothesis' was explored by Liboff et al. (1987) in an experiment involving incorporation of calcium-45 (n5Ca2*) in mixed human lymphocytes. The geomagnetic horizontal field component was'adjusted to 2l pT. The experiment was first performed at an amplitude of the applied oscillating field of 150 pT and a sharp minimum was obtained at the frequency of l43Hz, which corr

Genetic Determinants of Dyslipidemia

Dyslipidemia is a chronic deviation from normal blood lipid levels that can lead to atherosclerosis and other cardiovascular diseases; dyslipidemia and its sequelae are caused by the complex interplay of genetic and environmental factors. Although circulating concentrations of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein chole

Antenna Current Optimization using MATLAB and CVX

Antenna current optimization is a tool that offers many possibilities in antenna technology. Optimal currents are determined in the antenna design region and used for physical understanding, as a priori estimates of the possibilities todesign antennas, physical bounds and as figures of merits for antenna designs. Antenna current optimization is particularly useful for small antennas and antennas t

Prognostic instrument for survival outcome in melanoma patients : based on data from the population-based Swedish Melanoma Register

BACKGROUND: Several major analyses have identified a consistent set of independent risk factors for cutaneous malignant melanoma (CMM). A few prognostic models have been presented but some are based on a limited number of patients and others are based on selected groups of patients referred to major institutions. No nationwide population-based prognostic instrument for survival of CMM has been pre

Novel Approach to Controlled Surface Modification in Textile Via Magnetic Cross- Linked Enzyme Aggregates (Clea)

In this proceeding, architecting novel magnetic Cross-Linked-Enzyme-Aggregates (CLEA)nanoparticles to effectively and controllably modify textile surfaces without damaging the fabric itself, will bediscussed. The efficiency is due to exponentially increased surface concentration of biocatalyst and to thechoice of aggregate size which controls the penetration depth and hence preventing the fabric d

A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

BACKGROUND: Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterpart

Comorbidity in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory condition, which is associated with an increased risk of comorbidity from other diseases. RA disease severity is a major predictor of development of cardiovascular disease, serious infections and malignant lymphoma. This reflects the role of chronic inflammation in the underlying pathology. Recent surveys indicate that although clinical outcomes

A combined surveillance program and quality register improves management of childhood disability

PURPOSE: To describe a concept for prevention of secondary conditions in individuals with chronic neuromuscular disabilities by using two Swedish developed follow-up-programmes for cerebral palsy (CP; CPUP) and myelomeningocele (MMC; MMCUP) respectively as examples.METHOD: This paper describes and outlines the rationale, development and implementation of CPUP and MMCUP.RESULTS: Both programmes are

Melt processability and thermomechanical properties of blends based on polyhydroxyalkanoates and poly(butylene adipate-co-terephthalate)

The limited thermal stability of polyhydroxyalkanoates (PHAs) hinders their wide applicability, and methods to improve the processability of these biopolyesters are needed for efficient processing, e.g. by melt extrusion. In the present study we have shown by isothermal gravimetry, dynamic rheology and molecular weight analysis that the thermal stability of the PHAs at the processing temperature c

The accuracy of preoperative axillary nodal staging in primary breast cancer by ultrasound is modified by nodal metastatic load and tumor biology

Background The outcome of axillary ultrasound (AUS) with fine-needle aspiration biopsy (FNAB) in the diagnostic work-up of primary breast cancer has an impact on therapy decisions. We hypothesize that the accuracy of AUS is modified by nodal metastatic burden and clinico-pathological characteristics. Material and methods The performance of AUS and AUS-guided FNAB for predicting nodal metastases wa

A first-in-human, double-blind, randomised, placebo-controlled, dose ascending study of intra-articular rhFGF18 (sprifermin) in patients with advanced knee osteoarthritis

OBJECTIVES: To evaluate the safety of intra-articular sprifermin (primary), and to evaluate systemic exposure, biomarkers, histology, and other cartilage parameters in patients with advanced osteoarthritis (OA).METHODS: This was a first-in-human, double-blind, randomised, placebo-controlled trial of single and multiple ascending doses of sprifermin from 3-300 μg in knee OA patients scheduled for t