Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. It is therefore not surprising that these interactions also govern the response of our body´s defence mechanism, the so-called immune system, towards an infection. Understanding how proteins interact entails studying the binding affinity (strength) and the lifetime (dur

Acute respiratory distress syndrome (ARDS) is a life-threatening, high mortality pulmonary condition characterized by acute lung injury (ALI) resulting in diffuse alveolar damage. Despite progress regarding the understanding of ARDS pathophysiology, there are presently no effective pharmacotherapies. Due to the complexity and multiorgan involvement typically associated with ARDS, animal models rem

An evacuation experiment was carried out at the Äspö Hard Rock Laboratory in March 2018 to investigate human behaviour during evacuation in underground facilities via escape routes with long ascending tunnels. The objective of the experiment was to collect data that could be used as a basis for evacuation risk and safety assessments in underground tunnels and other large infrastructure projects re

Aims/Introduction: The incretin hormone glucose-dependent insulinotropic polypeptide (GIP) is secreted after meal ingestion. This study explored the relative influence of classes of macronutrients on GIP secretion. Materials and Methods: The human literature was revisited by identifying articles from PubMed using key words GIP, macronutrients, carbohydrates, fat, protein, healthy subjects. In mode

Aerosols and their interaction with clouds constitute the largest uncertainty in estimating the radiative forcing affecting the climate system. Secondary aerosol formation is responsible for a large fraction of the cloud condensation nuclei in the global atmosphere. Wetlands are important to the budgets of methane and carbon dioxide, but the potential role of wetlands in aerosol formation has not

Youth labour remained important well into the twentieth century, although it is often elusive in traditional sources. In this article, we investigate messengers – a category of occupational titles, including errand and office boys, which is thought of as youth jobs. We sketch the long-term development of the occupation by making use of digitised Swedish daily newspapers and discuss demand-side, su

Digital activism, political activism mediated by digital technologies, offers the promise of increased visibility and political power for marginalized groups. Yet, this has not been the case outside of a few exceptions such as Black Lives Matter. This paper offers theoretical, conceptual critical research that explores why successful digital activism may elude marginalized groups. We ask why many

Purpose: Previous studies have shown that at a similar body mass index, Middle Eastern immigrants are more insulin resistant and at higher risk for type 2 diabetes (T2D) than native Europeans. Insulin resistance is strongly associated with disturbed fat metabolism and cardiovascular disease (CVD). However, fat metabolism is poorly investigated comparing Middle Eastern and European ethnicities. Met

Introduction: Primary health care centers (PHCCs) in Sweden are struggling to maintain a balance between increasing demands of service and supervision and learning activities for a growing number of students. We sought a deeper understanding of primary care physicians and managers behavioral intention towards supervising, and their perceptions of the structural preconditions and support needed.Met

The aim of this paper is to shed light on the continuities and changes that far-right movements undergo throughout historical changes. It does so by focusing on the transnational and transgenerational dynamics through which the Legionary Movement fostered its existence from the settings of the Cold War exile to post-communist Romania. In order to illustrate these transnational and transgenerationa

The article sheds light on the significant fundraising and relief activities for Ireland during the Great Famine (1845–50) initiated in 1847 by the Italian philosopher and cleric Antonio Rosmini and his network in Savoy-Piedmont, Lombardy-Venetia and England. By analysing Rosmini's philosophical and political writings, the article demonstrates that Rosmini considered aid in times of crisis as an a