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Sex-and age-related variations in myocardial tissue composition of the healthy heart : a native T1 mapping cohort study

Aims: Cardiovascular diseases manifest differently in males and females, potentially influenced by inherent sex- and age-related differences in myocardial tissue composition. Such inherent differences are not well-established in the literature. With this study using cardiac magnetic resonance (CMR) native T1 mapping, we aim to determine the effect of sex and age on myocardial tissue composition in

Secondary Ice Production - current state of the science and recommendations for the future

Measured ice crystal concentrations in natural clouds at modest supercooling (temperature ~>−10°C) are often orders of magnitude greater than the number concentration of primary ice nucleating particles. Therefore, it has long been proposed that a secondary ice production process must exist that is able to rapidly enhance the number concentration of the ice population following initial primary ice

Biofilm-dispersed pneumococci induce elevated leukocyte and platelet activation

INTRODUCTION: Streptococcus pneumoniae (the pneumococcus) effectively colonizes the human nasopharynx, but can migrate to other host sites, causing infections such as pneumonia and sepsis. Previous studies indicate that pneumococci grown as biofilms have phenotypes of bacteria associated with colonization whereas bacteria released from biofilms in response to changes in the local environment (i.e.

PET-CT imaging of neuroendocrine tumours - Beyond diagnostics

Background: Neuroendocrine tumours (NETs) typically overexpress somatostatin receptors. By radiolabelling somatostatin analogues with a positron-emitting radionuclide (68Ga-DOTATOC or 68Ga-DOTATATE), these tumours can be detected with high sensitivity and specificity using somatostatin receptor positron emission tomography-computed tomography (PET-CT).Aim: To enhance knowledge about NETs imaged wi

Effects of a Paleolithic diet compared to a diabetes diet on leptin binding inhibition in secondary analysis of a randomised cross-over study

BACKGROUND: Beneficial effects from practising a Paleolithic diet as compared to a diabetes diet on weight, waist circumference, satiety, leptin, HbA1c and glucose control in randomised controlled trial participants with type 2 diabetes could be due to lower leptin resistance. Support for this hypothesis comes from an in vitro experiment that showed that digested wheat gluten, which is excluded fr

Elevated carbohydrate antigen 125 (CA125) is associated with incident heart failure and mortality in acute coronary syndrome

AIMS: Carbohydrate antigen 125 (CA125), a mucin produced by serosal cells in response to mechanical and inflammatory stimuli, has emerged as an important biomarker to guide risk stratification in heart failure (HF). The prognostic value of CA125 in acute coronary syndrome (ACS) patients is less explored.METHODS: In a cohort of 524 ACS patients (73% males, mean age 67 ± 12 years), we assessed the a

An Exhibition History of Latin American Art

An Exhibition History of Latin American Art compiles texts by twenty-one Latin American curators who were asked to select an exhibition that took place in Latin America or focused on the work of Latin American artists and justify its importance, relevance, and influence. The history of Latin American art exhibitions that is thus constructed considers the array of social and institutional contexts

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Translated PhD dissertation into Spanish.From the editors: ¿Es el arrepentimiento una forma de memoria?, ¿una manera de narrarnos a nosotros mismos?, ¿un acto de imaginación? Alejandro Cesarco ha desarrollado una práctica artística heterodoxa a partir de recursos como la repetición, la narratividad, la lectura o la traducción. Con este libro, en el que cuestiona un devenir del arte regido por el p

Role of the polyamine transporter PotABCD during biofilm formation by Streptococcus pneumoniae

Streptococcus pneumoniae is a bacterium of great global importance, responsible for more than one million deaths per year. This bacterium is commonly acquired in the first years of life and colonizes the upper respiratory tract asymptomatically by forming biofilms that persist for extended times in the nasopharynx. However, under conditions that alter the bacterial environment, such as viral infec

HAMLET, a human milk protein-lipid complex, modulates amoxicillin induced changes in an ex vivo biofilm model of the oral microbiome.

Challenges from infections caused by biofilms and antimicrobial resistance highlight the need for novel antimicrobials that work in conjunction with antibiotics and minimize resistance risk. In this study we investigated the composite effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells), a human milk protein-lipid complex and amoxicillin on microbial ecology using an ex vivo oral

Environmental sustainability in telecommunications: Exploring direct impacts of EU-headquartered telecom operators

The relevance of the ICT sector and telecom operators is predicted to grow rapidly within the next decade, mainly around their direct environmental impacts because of the ongoing expansion of mobile and fixed networks and increasing data traffic. Therefore, it is necessary to explore telecom operators' direct environmental impacts, considering the currently available information in sustainabil

Investor’s Intrinsic Motives and the Valence of Word-of-Mouth in Sequential Decision-Making : Modeling of Triple Serial Mediation

Word-of-Mouth (WoM) is a socially embedded process, and investors engage in social considerations to achieve self-motives. Investors attempt to share negative WoM (NWoM) to emotionally connect (self-affirm) to strengthen existing social ties following prior losses. In contrast, investors attempt to share positive WoM (PWoM) to self-enhance to attract others into developing new social ties. Thereby

Excess mortality in Denmark, Finland, Norway and Sweden during the COVID-19 pandemic 2020–2022

Background: The Nordic countries represent a unique case study for the COVID-19 pandemic due to socioeconomic and cultural similarities, high-quality comparable administrative register data and notable differences in mitigation policies during the pandemic. We aimed to compare weekly excess mortality in the Nordic countries across the three full pandemic years 2020–2022. Methods: Using data on wee

Smart Exploration Research Centre : Knowledge and innovation for exploration of critical raw materials

In response to the rising needs for long-term research and innovation in the field of critical raw material exploration, the Smart Exploration Research Centre was established in 2024 in Sweden. Funded by the Swedish Foundation for Strategic Research (SSF), this initiative involves collaboration among academic institutions, industry, and the public sector. Building on the H2020-funded Smart Explora

Reduktionen som erfarenhet : Kris och hoppfullhet i 1680-talets aristokratiska hushåll

A large body of scholarly work has been dedicated to the Swedish reduction in the early 1680s, when fiefs granted to the nobility were revoked as the crown strengthened its position. However, this research has focused on political and economic developments with an elite perspective. Insufficient attention has been paid to the actions and lived reality of other groups, not least the servants of the

Circulating Interleukin 17A and Other Inflammatory Proteins May Predict Cardiovascular Disease in Early Rheumatoid Arthritis

Objective. The objective of this study was to investigate the impact of 92 inflammatory proteins on the risk of cardiovascular disease (CVD) in patients with early rheumatoid arthritis (RA). Methods. This study included consecutive patients with early RA recruited between 1995 and 2002. Stored plasma samples were analyzed for 92 inflammatory proteins. CVD diagnoses were retrieved from national in-