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High-grade serous ovarian cancer (HGSOC) is a major health concern for women due to its subtle onset, aggressive progression, high recurrence rate, and resistance to standard therapies. Olaparib, a PARP inhibitor, is currently used as maintenance therapy following removal of tumors. C26A6 is a promising therapeutic which has been shown to inhibit breast cancer progression in mouse models by disrup
Focusing on mounting challenges to agro-industrial capitals posed by emerging infectious diseases, this paper revisits longstanding debates in critical agrarian studies scrutinizing the role of turnover time. Analyzing Norway and Denmark's poultry industries' recent confrontations with avian influenza, and by paying close attention to the questions of temporality and disaggregating the agency of c
This study examines how Instagram’s platformized ecosystem shapes imaginaries of #sustainableconsumption. Using networked content analysis of 9,809 posts, we identify three platformized imaginaries—systemic sustainability transitions, ethical consumer lifestyle, and zero-waste living practices. Findings reveal how platformization constrains sustainable consumption discourses, embedding them within
Review of "Photosynthesisers: Women and the lens" a group exhibition curarted by James Gatt at Te Uru Waitākere Contemporary Gallery, Auckland.
Att kunna identifiera outnyttjad byggrätt är en angelägenhet hos såväl privata som offentliga aktörer. För privata aktörer uppstår detta behov exempelvis vid nybyggnadsprojekt och för offentliga kan ett annat behov istället vara att ha bättre koll på sin planberedskap. Att söka och beräkna byggrätten manuellt kan ta tid och för privata aktörer kan detta även leda till missade möjligheter. Ett digiBeing able to identify unused development rights is of interest for both private and public actors. For private actors, this need arises, for example, in new construction projects, and for public actors, another need may instead be to have better control over their planning readiness. Searching and calculating development rights manually can be time consuming and for private actors this can also l
Mesosiderites are rare, differentiated meteorites, so-called stony-iron meteorites—they are impact breccias composed of an unusual mix of crustal basalt and pyroxenite, core-derived metal, but no mantle materials. This odd mixture makes their origin enigmatic and has inspired many different formation theories over the last several decades. Some of the outstanding questions have regarded the origin
This Study Protocol article outlines the aims, theory, and methodology of a 4-year project that primarily seeks toenhance our understanding of the role of starting age and Extramural English. The project unravels the language proficiencyof individuals studying English as a foreign or second language (L2) who encounter substantial exposure to English outsideschool (extramural English, EE), but begiThis Study Protocol article outlines the aims, theory, and methodology of a 4-year project that primarily seeks to enhance our understanding of the role of starting age and Extramural English. The project unravels the language proficiency of individuals studying English as a foreign or second language (L2) who encounter substantial exposure to English outside school (extramural English, EE), but b
Music and Performing Arts is one of the fields Georgia can pride itself on internationally. While the country is in transition as it officially embarks on its long path to the European Union membership, this study explores the process of Europeanization of Higher Music Education in Georgia. Authors analyze how Higher Music Educational Institutions employ European projects for organizational change
In this study of human carotid endarterectomy plaques (using 1128 regions of interest in a total of 10 plaques), we found that photon counting computed tomography (PCCT) can differentiate between attenuation and the spectral patterns of calcium, intra-plaque haemorrhage, thrombus, fibrosis, necrosis and lipid core. This is the first study to show the potential of PCCT in living patients using clin
Background: Multimarker panels of blood-borne biomarkers could aid in shortening the diagnostic delay of pulmonary arterial hypertension (PAH). Research Question: Can any of the 61 proteins included in the study, related to pathways known to be involved in PAH pathophysiology (eg, coagulation, inflammation, fibrosis), differentiate PAH from other forms of pulmonary hypertension (PH) and/or dyspnea
An experiment was conducted to investigate the extent to which training in Bayesian thinking helps lawyers to recognize probabilistic fallacies in reasoning about legal evidence. The study showed that a limited amount of training (5 h) led to a significant improvement. However, some probabilistic fallacies emerged as more deceptive than others. The inversion fallacies (true-positive inversion and
