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Association of Immune Marker Changes with Progression of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma

Importance: Multiple myeloma is consistently preceded by monoclonal gammopathy of undetermined significance (MGUS). Risk models that estimate the risk of progression from MGUS to multiple myeloma use data from a single time point, usually the initial workup. Objective: To longitudinally investigate the alterations of serum immune markers with stable vs progressive MGUS. Design, Setting, and Partic

Massive MIMO From a Terminal Perspective

This thesis focuses on the terminal aspects of massive MIMO systems. Based on the degree of freedom a terminal have in a MaMi, different antenna configurations, transceiver topologies with associated transmission schemes, and the underlying algorithms are researched.The first studied topic concerns multiple-antenna terminals in a massive MIMO system for sub-6 GHz, operated at the center frequency

Monitoring moisture distribution in textile materials using grating interferometry and ptychographic X-ray imaging

Employing two recently developed X-ray imaging techniques, we investigated methods for observing moisture at different length scales in organic fibers and textiles. Using the coherent diffractive imaging technique of ptychographic tomography, structural features in a single coated wool fiber in both dry and humid conditions were observed at about 200 nm resolution. The reconstructed three-dimensio

Grating-based X-ray dark-field imaging : a new paradigm in radiography

Grating-based X-ray dark-field contrast is an emerging new imaging modality that is demonstrating particularly high potential for radiography. The signal in dark-field X-ray imaging is determined by small-angle X-ray scattering at structures typically below the spatial resolution of the imaging setup. Thus, this technique not only yields complementary information but also visualizes information th

Interaction between serum levels of Anti-Mullerian Hormone and the degree of sperm DNA fragmentation measured by sperm chromatin structure assay can be a predictor for the outcome of standard in vitro fertilization

Serum levels of Anti-Mullerian Hormone (AMH) have been shown to be biomarker for prediction of the quantitative aspects of ovarian reserve. On the male side, sperm chromatin structure assay (SCSA) DNA fragmentation index (DFI) has been demonstrated to be an important predictor of outcomes in standard IVF procedures but to less degree in intracytoplasmic sperm injection procedures (ICSI). The purpo

Magnesium and potassium status in healthy subjects as assessed by analysis of magnesium and potassium in skeletal muscle biopsies and of magnesium in mononuclear cells

Magnesium and potassium concentrations were determined in plasma, erythrocytes and urine collected during 24 h, and in percutaneous muscle biopsies obtained in 30 healthy subjects. Magnesium was also analyzed in mononuclear cells. Men, compared to women, showed a higher urinary excretion of magnesium (p less than 0.05). The magnesium contents in mononuclear cells correlated significantly with the Magnesium and potassium concentrations were determined in plasma, erythrocytes and urine collected during 24 h, and in percutaneous muscle biopsies obtained in 30 healthy subjects. Magnesium was also analyzed in mononuclear cells. Men, compared to women, showed a higher urinary excretion of magnesium (p less than 0.05). The magnesium contents in mononuclear cells correlated significantly with the

Measurements of magnesium in mononuclear cells

In this study analysis of magnesium in mononuclear cells was compared to that in muscle in patients and healthy controls. Mononuclear cell concentrations of magnesium expressed as nmol/mg cell protein correlated significantly with muscle biopsy concentrations of magnesium (r = 0,68; p less than 0,001). Hence, we suggest that analyzing of magnesium in mononuclear cells could be an easy and convenie

Dynamic extraction coupled on-line to liquid chromatography with a parallel sampling interface—a proof of concept for monitoring extraction kinetics

On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the

Mirror QCD and cosmological constant

An analog of Quantum Chromo Dynamics (QCD) sector known as mirror QCD (mQCD) can affect the cosmological evolution due to a non-trivial contribution to the Cosmological Constant analogous to that induced by the ground state in non-perturbative QCD. In this work, we explore a plausible hypothesis for trace anomalies cancellation between the usual QCD and mQCD. Such an anomaly cancellation between t

Quantum Yang-Mills dark energy

In this short review, I discuss basic qualitative characteristics of quantum non-Abelian gauge dynamics in the non-stationary background of the expanding Universe in the framework of the standard Einstein-Yang-Mills formulation. A brief outlook of existing studies of cosmological Yang-Mills fields and their properties will be given. Quantum effects have a profound impact on the gauge field-driven

DVCS off deuteron and twist three contributions

We study the deeply virtual Compton scattering off a spin-one particle, which is exemplified by the case of coherent scattering on a deuteron target. We discuss the role of twist three contributions for restoring the QED gauge invariance of the amplitude corresponding to this process. We consider both kinematical and dynamical sources of twist three generalized parton distributions.

Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia : A Retrospective Multinational Study

PURPOSE: We determined the prognostic factors and utility of allogeneic hematopoietic cell transplantation among children with newly diagnosed hypodiploid acute lymphoblastic leukemia (ALL) treated in contemporary clinical trials.PATIENTS AND METHODS: This retrospective study collected data on 306 patients with hypodiploid ALL who were enrolled in the protocols of 16 cooperative study groups or in

Convergence properties of Lévy expansions: implications for Odderon and proton structure

We detail here the convergence properties of a new model-independent imaging method, the Lévy expansion, that seems to play an important role in the analysis of the differential cross section of elastic hadron-hadron scattering.We demonstrate, how our earlier results concerning the Odderon effects in the differential cross-section of elastic proton-proton and proton-antiproton scattering as well as t