Primary mitochondrial diseases are a heterogeneous group of rare genetic disorders affecting approximately 125 persons per million. Mutations underlying these diseases give rise to biological changes (including decrease in cellular energy production and increase in reactive oxygen species), leading to organ failure, and commonly early morbidity. Mitochondrial diseases often present in early childh

As the modern society becomes larger and increasingly diverse, its problems become more elusive and solutions far-fetched. This puts pressure on relevant education. Geographical knowledge, whose raison d’être has always been to deal with complexity, should therefore be in high demand, but isn’t. In this presentation we want to investigate why this is the case, by outlining three major problems geo

The case that constitutes the subject for this paper is a voluntourism project organized in the Faroe Islands that has gained worldwide attention. Unskilled volunteers were called to perform maintenance works while popular hiking trails remained closed for regular tourists. Thousands applied to build and mark trails in exchange for bed and board, while the idea was a successful marketing campaign

PURPOSE: The overall aim of this study was to describe experiences of discrimination due to inaccessibility among people using mobility devices.MATERIAL AND METHODS: We conducted a thematic qualitative analysis of 88 complaints about wheeled mobility device use, inaccessibility, and discrimination submitted to the Swedish Equality Ombudsman (DO) during 2015 and 2016.RESULTS: The analysis resulted

Objective. The objective of this study was to explore whether recombinant GAD65 conjugated hydroxide (GAD-alum) treatment affected peripheral blood T-cell subpopulations in healthy children with multiple beta cell autoantibodies. Method. The Diabetes Prevention–Immune Tolerance 2 (DiAPREV-IT 2) clinical trial enrolled 26 children between 4 and 13 years of age, positive for glutamic acid decarboxyl

BACKGROUND: Cut-points to define slow walking speed have largely been derived from expert opinion. METHODS: Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% me

Cell-Free networking is one of the prime candidatesfor 6G networks. Despite being capable of providing the 6Gneeds, practical limitations and considerations are often neglectedin current research. In this work, we introduce the conceptof federations to dynamically scale and select the best set ofresources, e.g., antennas, computing and data resources, to servea given application. Next to communica