Adenovirus type 9 was inoculated sc into newborn Wistar/Furth rats, divided into four groups: (1) six male rats, not treated further; (2) 11 male rats, castrated at 4 weeks of age; (3) 12 male rats, castrated at 4 weeks of age and subsequently treated repeatedly with estrogen; and (4) 12 female rats, not treated further. All of the rats in group 3 developed mammary hyperplasia and tumors (fibroade

Background: ACMG/AMP and AMP/ASCO/CAP have released guidelines for variation interpretation, and ESHG for diagnostic sequencing. These guidelines contain recommendations including the use of computational prediction methods. The guidelines per se and the way they are implemented cause some problems. Methods: Logical reasoning based on domain knowledge. Results: According to the guidelines, several

Background: Homograft tissue is an important reconstructive material used in the surgical correction of a variety of congenital heart defects. The aim of this study is to evaluate the long-term outcome of pulmonary artery (PA) branch patches used in the reconstruction of the thoracic aorta in children. Methods: Retrospective review of 124 consecutive pediatric patients undergoing corrective surger

Ambitious climate policies have distributional consequences. These require countervailing social policies to keep climate targets acceptable for the electorate. This article analyses data from the European Social Survey as to whether attitudes in relation to climate and welfare policies converge or diverge. It distinguishes four types of social-ecological attitudes: ‘Synergy’ or support for both k

The influence of car brake system parameters on particulate matter emissions was investigated using a pin-on-disc tribometer. Samples from a low-steel friction material and a cast iron disc were tested for different sliding velocities, nominal contact pressures and frictional powers. Disc temperatures were also measured. Their impact on total concentration, size distribution, particle coefficient

Particle emissions originating from the sliding disc brake contact in disc brakes are a main contributor to PM10 in Europe. The macroscopic friction and wear behaviour can be explained, at the mesoscopic scale level, by the growth and destruction of contact plateaus. This paper further develops a cellular automaton that describes the mesoscopic contact situation by implementing friction, wear, and

In this paper, we generalize the one-bit quantized low resolution RELAX algorithm to allow for exponentially decaying modes. The resulting greedy algorithm exploits a time-varying threshold to allow for the estimation of the parameters detailing the modes. The improvement offered by the proposed algorithm as compared to its predecessor, and the corresponding Cramér-Rao Lower Bound, is illustrated

The project “Energy and Society”, sponsored by the Swedish Secretariat for Futures Studies, has studied different indigenous alternatives to imported oil in Sweden. Having no domestic oil, gas or coal, Sweden is 70% dependent on imported oil. This will have to change, either due to resource depletion within the next several decades, or due to oil-rich countries limiting export. Both Nuclear Sweden

In this study the effect of irrigation by dam water in Bigherd area (Fars province, Iran) on groundwater quality one and three years after Dam construction was investigated. To conduct this study the major ion concentrations, including HCO3−, Ca2+, Mg2+, Na+, K+, SO42− and Cl−, and water levels in 10 water wells and the dam reservoir were measured during two periods (June 2009 and June 2011), anal

The aim of the present paper is to investigate the level of airborne wear particles released during the dyno-bench tests with the brake pads consisting of alkali-activated slag as an abrasive. Airborne wear particles are generated with a full-scale dyno-bench adapted for airborne wear particles emission studies. The tested disc brake is equipped with two semi-metallic brake pads and a grey cast ir

We suggest that one way to help students to integrate psychology into their social work education is through case discussions which are routinely used in social work education to illustrate the realities encountered by social workers in their everyday practice. Literature suggests that case discussions help the students bridge the gap between theory and practice, enhance understanding of the compl

Many thermophilic bacteria are efficient biomass degraders (producing polysaccharide degrading enzymes and utilizing a great variety of substrates, e.g. lignocellulosic polymers, pentoses, hexoses, as well sugar acids, and sugar alcohols). This makes them interesting organisms as potential cell factories in a circular bioeconomy. Lignocellulosic and marine macroalgal biomasses are regarded as sust

Artikeln undersöker eurons konsekvenser för integration och tillväxt i Östersjöregionen (Polen, Litauen, Lettland, Estland, Finland och Sverige). Efter Sovjetunionens sammanbrott har de baltiska staterna och Polen snabbt hämtat in på Västeuropa. Den globala finanskrisen blev ett kraftigt bakslag för de förra, men i mindre utsträckning för Polen. Penningpolitiken har gjort skillnad: den polska zlotWhich have been the consequences of the euro for integration and economic performance in the Baltic Sea region? After the collapse of the Soviet Union, the three Baltic states and Poland have been rapidly catching-up with Western Europe. The Great Recession becamea great setback for the former, while less so for Poland. A difference is the monetary policy: the Polish zloty depreciated in the criti

Adult foreign language acquisition is challenging, and the degree of success varies among individuals. Anatomical differences in brain structure prior to training can partly explain why some learn more than others. We followed a sample of conscript interpreters undergoing intense language training to study learning-related changes in white-matter microstructure (FA, MD, RD and AD) and associations

Airborne wear particles originating from disc brakes are one important contributor to the concentration of airborne particles in urban environments. It is therefore of interest to improve the knowledge of these particles. The purpose of this article is to investigate the concentration and size distribution of the airborne wear particles generated from the contact between a low-metallic pad materia

The activation of the kallikrein-kinin system is thought to be one of the pathophysiological factors in acute pancreatitis. A radioimmunoassay for porcine, pancreatic tissue kallikrein was developed and used to measure levels in normal plasma and peritoneal fluid and in experimental, bile-induced (group A) and bile trypsin-induced (group B) acute pancreatitis in the pig. Normal porcine plasma and

The management of non-muscle-invasive bladder cancer (NMIBC) has evolved from the first reports on bladder endoscopy and transurethral resection to the introduction of adjuvant intravesical treatment. However, disease recurrence and progression remain an ongoing risk, placing a heavy burden on healthcare resources and on patients’ quality of life. Deeper understanding of the molecular basis of the