The rapid advancement of imaging technologies in pathology has ushered in an era of data-intensive diagnostic workflows, generating large volumes of data that demand sophisticated segmentation and compression techniques. Chemical imaging approaches offer an all-digital objective approach to pathological analysis, though image segmentation is required for efficient computation. Convolutional autoen

Introduction: Oats, a highly nutritious cereal known for their health benefits, contain various macromolecules of significant biological value, including abundant and highly digestible proteins. Despite their importance, oat proteins have not been extensively studied. Here, we present a complete set of the expressed globulins genes, which code for the main storage protein in oats as well as their

Non-pharmacological interventions represent the first-line treatment approach for patients with non-cardiac syncope. These interventions include reassurance of the benign nature of syncope, education about triggers and strategies to avoid them, early recognition of prodromal symptoms, and lifestyle measures to counteract blood pressure falls. Adequate water intake is recommended to avoid hypovolem

We provide an outline of the proof of the Donovan–Wemyss Conjecture in the context of the Homological Minimal Model Program for threefolds. The proof relies on results of August, of Hua and the second-named author, Wemyss, and on the Derived Auslander–Iyama Correspondence—a recent result by the first- and third-named authors.

Men outnumber women as military drone operators, both in media narratives and in reality, as prominent Western militaries such as the US and the UK have far more men than women in their ranks. In recent years, Russia’s invasion of Ukraine has brought newfound attention to the use of drone warfare; specifically, how the media overwhelming spotlights male drone operators. However, portrayals of wome

Background and purpose — First-line treatment (education, exercise) for patients with hip and knee osteoarthritis (OA) aims to reduce pain and improve function. We aimed to compare progression to joint replacement within 5 years between responders and non-responders to first-line treatment for hip and knee OA, respectively. Methods — This observational study included data for 30,524 knee OA and 13

Increased global migration to welfare states puts pressure on successful integration. Successful integration is broadly associated with entry into the labour market. Therefore, integration is measured through employment. Attempts to increase migrant involvement in the labour market are often made by street-level organisations, where interactions between individuals from the private and/or public s

We argue that we should be sceptical towards the claim that there is such a thing as the standing to blame someone privately, understood in terms of holding the attitude of blame. Key features of the idea about standing to blame do not apply to private blame. For example, we argue that private blame is not the exercise of some normative power, and it is not even pro tanto wrong for a hypocrite to

Ambulance travel time estimations play a pivotal role in ensuring timely and efficient emergency medical care by predicting the duration for an ambulance to reach a specific location. Overlooking factors such as local traffic situations, day of the week, hour of the day, or the weather may create a risk of inaccurately estimating the ambulance travel times, which might lead to delayed emergency re

Purpose: Etoposide to standard R-CHOP is used for high-risk diffuse large B-cell lymphoma (DLBCL) in some countries. Due to the lack of randomized trials, a real-world data study using matching methods was used to test the potential effectiveness of R-CHOEP over R-CHOP. Patients and Methods: This study included patients from the Danish Lymphoma Register diagnosed between 2006 and 2020 at the age o

Artificial intelligence and Machine Learning (AI/ML) are steadily becoming widespread across all layers in the current mobile network generation. The next generation of networks, namely 6G, will consider AI/ML as a foundational block to deliver all expected results of such networks. Thus, the management of AI/ML applications across different layers of 6G is paramount for the success of the next ge

Bone is a complex hierarchical structure mainly comprising of a matrix of collagen and hydroxyapatite. The main physiological functions of bone include regulating skeletal remodeling, calcium homeostasis and providing a congenial environment to the bone marrow cells to reside and these physiological processes are intricately regulated by various cell types and biomolecules. During trauma to the sk

While misinformation has been around for centuries, the effects of online brand-related misinformation on consumers’ engagement remain tenuous. Addressing this gap, we develop the concept of online brand-related misinformation engagement, a consumer’s (e.g. cognitive/emotional) resource investment in their interactions with misinformation about brands. Recognizing the persuasive nature of misinfor

Ambient pressure X-ray photoelectron spectroscopy (APXPS) is combined with simultaneous electrical measurements and supported by density functional theory calculations to investigate the sensing mechanism of tungsten disulfide (WS2)-based gas sensors in an operando dynamic experiment. This approach allows for the direct correlation between changes in the surface potential and the resistivity of th

INTRODUCTION: Recent clinical trials of amyloid beta (Aβ)-targeting therapies in Alzheimer's disease (AD) have demonstrated a clinical benefit over 18 months, but their long-term impact on disease trajectory is not yet understood. We propose a framework for evaluating realistic long-term scenarios. METHODS: Results from recent phase 3 trials of Aβ-targeting antibodies were integrated with an estim

IntroductionPatients with congenital heart disease (ConHD) are at increased risk for adverse cardiac events. Predicting long-term outcomes and guidance of patient management might benefit from a range of (new) biomarkers. This is a rapidly evolving field with potentially large consequences for clinical decision making. With a systematic review of available biomarkers in ConHD we identified the cli

Globally, boreal forests act as important carbon sinks, however, drought and forest management could substantially alter the sink strength, though the controlling mechanisms of drought and management remain unclear. In this study, we combined the detailed process-based CoupModel with multiple measurements to study the impacts of recent drought and forest thinning on a boreal forest during 2018–202

Repair or reconstruction after a peripheral nerve injury is a challenge because functional outcome is still unsatisfactory. Treatment in patients with diabetes may be further demanding. Nerve regeneration after nerve injury was investigated, using various repair and reconstruction models, including immediate and delayed repair, bioengineered conduits, or nerve autografts as well as a possibility t

The book offers an overview of the history, cases and material of the European Law Moot Court Competition (ELMC). The ELMC is today considered the most prestigious moot court within the field of European Union Law and one of the most important moot court competitions in the world.Published at the occasion of the 35th anniversary of the competition, the book aims to both motivate students and guide

BACKGROUND: The COVID-19 pandemic has highlighted the importance of evidence-informed priority setting and situational analysis in pandemic preparedness and response. Health Technology Assessment (HTA) has been identified as an essential tool for evidence-informed decision-making in healthcare. However, the potential role of HTA in pandemic preparedness and response in Africa has yet to be explore