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Deep learning-based evaluation of normal bone marrow activity in 18F-NaF PET/CT in patients with prostate cancer

Purpose: Bone marrow is the primary site of skeletal metastases in prostate cancer. 18F-sodium fluoride (NaF) can be used to detect malignant activity, but also identifies irrelevant degenerative cortical uptake. Normal radiotracer activity in solely the marrow has yet to be described and could be a first step towards automated tumor burden calculation as SUV thresholds. We aimed to investigate no

Transatlantic multicenter study on the use of a modified preloaded delivery system for fenestrated endovascular aortic repair

Objective: Analyze the outcomes of endovascular complex abdominal and thoracoabdominal aortic aneurysm repair using the Cook fenestrated device with the modified preloaded delivery system (MPDS) with a biport handle and preloaded catheters. Methods: A multicenter retrospective single arm cohort study was performed, including all consecutive patients with complex abdominal aortic aneurysm repair an

Effects of the DICE Method to Improve Timely Recognition and Treatment of Neuropsychiatric Symptoms in Early Alzheimer's Disease at the Memory Clinic : The BEAT-IT Study

Background: Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-pharmacological interventions are scarcely implemented. Objective: To evaluate the effectiveness of the Describe, Investigate, Create, Evaluate (DICE) method™ to improve the care for NPS in AD

Pain intensity and psychological distress show different associations with interference and lack of life control : A clinical registry-based cohort study of >40,000 chronic pain patients from SQRP

Background: Both chronic pain and depressive and/or anxiety symptoms are associated with negative impacts on daily living, including interference and lack of life control. However, little is known about how pain and psychological distress affect these impacts. Aim: The first aim was to assess how pain intensity, psychological distress, and social support interact with interference and lack of life

The Historical Gender Gap Index: A Longitudinal and Spatial Assessment of Sweden, 1870-1990

This paper investigates the evolution of gender equality in Sweden during a phase characterized by industrialization, urbanization, and demographic transition. To this end, we build a database with quantitative indicators to construct a spatial Historical Gender Gap Index. We find that after a period of stagnation, Sweden made significant progress in closing the gender gap from the 1940s onward to

Circumferential Measurements to Calculate Lower Limb Volume in Persons with Lymphedema : What Segment Length Is to Be Recommended?

Background: Circumferential measurements (CMs) every 4th cm are commonly used to assess lower limb volume (LLV), but fewer measurements would be less time-consuming. The aim of this study was therefore to establish the agreement between LLV measurements derived from CM every 4th cm (V4), 8th cm (V8), and 12th cm (V12), and to evaluate the intrarater test-retest reliability for each of the three me

Σ (1385) ± resonance production in Pb–Pb collisions at √sNN=5.02 TeV

Hadronic resonances are used to probe the hadron gas produced in the late stage of heavy-ion collisions since they decay on the same timescale, of the order of 1–10 fm/c, as the decoupling time of the system. In the hadron gas, (pseudo)elastic scatterings among the products of resonances that decayed before the kinetic freeze-out and regeneration processes counteract each other, the net effect dep

Why the European Commission’s ‘pragmatic’ approach to asylum is not enough: Re-imagining solidarity as a new form of conducting regional politics

The failure of the EU and its Member States to adequately respond to increased refugee movements since 2015, has caused disagreement on how the principle of solidarity and fair sharing of responsibility should be given effect in the context of a reformed European policy on migration. In September 2020, theEuropean Commission proposed the new Pact on Migration and Asylum which was meant to promote

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states. Previous genetic studies have largely focused on insulin resistance in the fasting state, where hepatic insulin action dominates. Here we studied genetic variants influencing insulin levels measured 2 h after a glucose challenge in >55,000 participants from three ancestry groups. We identified ten new lo

Search for high-mass Wγ and Zγ resonances using hadronic W/Z boson decays from 139 fb −1 of pp collisions at √s = 13 TeV with the ATLAS detector

A search for high-mass charged and neutral bosons decaying to Wγ and Zγ final states is presented in this paper. The analysis uses a data sample of s = 13 TeV proton-proton collisions with an integrated luminosity of 139 fb −1 collected by the ATLAS detector during LHC Run 2 operation. The sensitivity of the search is determined using models of the production and decay of spin-1 charged bosons and

Alphabetic Excavations : Johannes Bureus and the Runic Kabbalah

Around the turn of the 17th century, the Swedish antiquary and mystic Johannes Bureus (1568–1652) claimed to have discovered the primordial theology and science of his Scandinavian ancestors encoded in their system of writing, the runic alphabet, inspired in large part by earlier Christian interpretations of the Kabbalah. In the leadup to the Swedish intervention in the Thirty Years’ War, he viewe

Rethinking Gender in Orthodox Christianity

What is the role of gender in Eastern Christianity? In this volume, Orthodox experts of different disciplines and cultural backgrounds tackle this complex question. They engage critically with gender issues within their own tradition. Rather than simply accepting pervasive assumptions and practices, the authors challenge readers to reconsider historically or theologically justified views by offeriWhat is the role of gender in Eastern Christianity? In this volume, Orthodox experts of different disciplines and cultural backgrounds tackle this complex question. They engage critically with gender issues within their own tradition. Rather than simply accepting pervasive assumptions and practices, the authors challenge readers to reconsider historically or theologically justified views by offeri