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Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program

Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes Prevention Program to test the hypotheses that a genetic risk score (GRS) based on deleterious alleles at 32 lipid-associated single-nucleotide polym

Lifetime measurements and calculations in Y+ and Y2+ ions

We report a new set oftheoretical transition probabilities in Y II, obtained using a multiconfiguration relativistic Hartree-Fock method including core polarization. The overall quality of the calculations is assessed by comparisons with new and previous lifetime measurements. In this paper, we report new measurements of five lifetimes in the 4d5p and 5s5p configurations, in the energy range of 32

Properties of odour plumes from natural baits

The formation of an odour trail can be broken down into a chain of events: first, the emission of the attractant from the bait, second, a turbulent mixing into the immediate surroundings and third, a downstream advection and dispersion of the attractant by the current flowing past the bait. In this work, a simple analysis of the physical processes governing the first two stages shows that the release

How migration motives change over distance: evidence on variations across socioeconomic and demographic groups

Migration researchers have long known that the motives for changing place of residence vary over migration distance. Typically, short-distance moves are regarded as motivated by housing considerations and longer-distance moves primarily by employment considerations. Using a large-scale survey on migration motives, this paper explores how migration motives change over migration distance. Particular

GCM characteristics explain the majority of uncertainty in projected 21st century terrestrial ecosystem carbon balance

One of the largest sources of uncertainties in modelling of the future global climate is the response of the terrestrial carbon cycle. Studies have shown that it is likely that the extant land sink of carbon will weaken in a warming climate. Should this happen, a larger portion of the annual carbon dioxide emissions will remain in the atmosphere, and further increase global warming, which in turn

Why human rights fail to protect undocumented migrants

In this article, I depart from the factual difficulties of undocumented migrants to access a state’s protection mechanisms for avowedly universal human rights. I relate this aporia to two competing conceptions of territorial jurisdictions. Drawing on the Convention on the Rights of the Child and the Migrant Workers Convention, I separate the sphere of the political community (the polis) and that o

Importance of Inoculum Properties on the Structure and Growth of Bacterial Communities during Recolonisation of Humus Soil with Different pH.

The relationship between community structure and growth and pH tolerance of a soil bacterial community was studied after liming in a reciprocal inoculum study. An unlimed (UL) humus soil with a pH of 4.0 was fumigated with chloroform for 4 h, after which < 1 % of the initial bacterial activity remained. Half of the fumigated soil was experimentally limed (EL) to a pH of 7.6. Both the UL and the EL

Solar energy for electricity and fuels.

Solar energy conversion into electricity by photovoltaic modules is now a mature technology. We discuss the need for materials and device developments using conventional silicon and other materials, pointing to the need to use scalable materials and to reduce the energy payback time. Storage of solar energy can be achieved using the energy of light to produce a fuel. We discuss how this can be ach

On channel quantization for multi-cell cooperative systems with limited feedback

Coherent multi-cell cooperative transmission, also referred to as coordinated multi-point transmission (CoMP), is a promising strategy to provide high spectral efficiency for universal frequency reuse cellular systems. To report the required channel information to the transmitter in frequency division duplexing systems, limited feedback techniques are often applied. Considering that the average ch

Factors affecting obstetric outcome of singletons born after IVF

BACKGROUND: Singletons born after IVF have an adverse perinatal outcome when compared with singletons in the general population. This study investigates maternal characteristics and IVF-treatment-related variables, for a possible influence on obstetric outcomes. METHODS: Data from all IVF clinics in Sweden, including all IVF singletons born after fresh treatment cycles and own oocytes during 2002-

Cyclists in roundabouts -- Different design solutions.

Whether the safest roundabout design for cyclists is to separate cycle crossings or integrate cyclists with motorists is an extensively discussed issue. Studies using accident statistics indicate that a separated cycle crossing is the safest for high motor vehicle volumes. However, the results have not been satisfyingly explained. This article combines quantitative and qualitative methods in traff

Lack of Opsonic Antibody Responses to Invasive Infections With Streptococcus dysgalactiae

Introduction: Streptococcus dysgalactiae can cause severe recurrent infections. This study aimed to investigate antibody responses following S. dysgalactiae bacteraemia and possible development of protective immunity. Materials and Methods: Patients with S. dysgalactiae bacteraemia in the county of Skåne between 2017 and 2018 were prospectively included. Acute and convalescent sera were obtained.

New and Practical Formulation for Overlaps of Bogoliubov Vacua

In this Letter, we present a new expression for the overlaps of wave functions in Hartree-Fock-Bogoliubov based theories. Starting from the Pfaffian formula by Bertsch et al. [1], an exact and computationally stable formula for overlaps is derived. We illustrate the convenience of this new formulation with a numerical application in the context of the particle-number projection method. This new fo

Näthat och demokratiskt deltagande – en kunskapsöversikt

Rätten att uttrycka åsikter, att kritisera och att ifrågasätta är en del av enlevande demokrati. Ett demokratiskt samhälle måste vara öppet för olikaröster och ge alla möjlighet att komma till tals. Demokratin är beroendeav att människor deltar och engagerar sig i samhällsfrågor. Med rättentill yttrandefrihet kommer också ett ansvar. Var och en bör skydda, värnaoch bevara yttrandefriheten genom at

MTT and Blood-Brain Barrier Disruption within Asymptomatic Vascular WM Lesions

BACKGROUND AND PURPOSE: White matter lesions of presumed ischemic origin are associated with progressive cognitive impairment and impaired BBB function. Studying the longitudinal effects of white matter lesion biomarkers that measure changes in perfusion and BBB patency within white matter lesions is required for long-term studies of lesion progression. We studied perfusion and BBB disruption with

Listening effort and fatigue in native and non-native primary school children

Background noise makes listening effortful and may lead to fatigue. This may compromise classroom learning, especially for children with a non-native background. In the current study, we used pupillometry to investigate listening effort and fatigue during listening comprehension under typical (0 dB signal-to-noise ratio [SNR]) and favorable (+10 dB SNR) listening conditions in 63 Swedish primary s

Patients and Professionals as Partners in Hypertension Care : Qualitative Substudy of a Randomized Controlled Trial Using an Interactive Web-Based System Via Mobile Phone

BACKGROUND: The use of technology has the potential to support the patient´s active participation regarding treatment of hypertension. This might lead to changes in the roles of the patient and health care professional and affect the partnership between them.OBJECTIVE: The aim of this qualitative study was to explore the partnership between patients and health care professionals and the roles of p

Inre motivation positiv för elevers utveckling och lärande

Har yttre belöningar (exempelvis guldstjärnor i kanten av skrivboken) en negativ inverkan på elevers inre motivation? Minskar intresset för människor att engagera sig i eller prestera väl i en uppgift när yttre belöningar erbjuds? Flera meta-analyser har visat att så är fallet. Self-Determination Theory (SDT) är en teori som såväl teoretiskt som praktiskt belyser hur lärare kan stödja elever för a