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Amperometric Biosensors for Detection of Analytes in Cellular Models

Various biological problems such as disease mechanisms, drug development and toxicological studies motivated the introduction of cellular models that today also represent an alternative for reducing the use of animals in controversial medical and pharmaceutical experiments. Cells are complex matrices where several processes occur simultaneously. Because of this, analytical methods with specific p

Artificial Life goes 'in Silico'

The paper reviews a number of Cellular Neural Network implementation on a Field-programmable Gate-array. It shows by a number of experiments, how these implementations can be used to create dynamic, autonomous processes for applications ranging from computer games to robot navigation.

Combustion Bowl Heat Transfer Analysis in Diesel and PPC Engines

Popular Abstract in Swedish Transporter är viktiga för ett fungerande samhälle, men samtidigt innehåller avgaserna från en förbränningsmotor farliga utsläpp som förorenar vår miljö. Kan vi på något sätt hindra att miljön blir förstörd av farliga utsläpp genom förbättrad motordesign? Frågan om global uppvärmning har varit vid liv enda sedan IPCC (Intergovernmental Panel on Climate Change) grundadeThis thesis concerns a numerical investigation on heat transfer in internal combustion engines, with the aim of increasing engine efficiency. The efficiency gains are to be extracted from reduced heat transfer losses, by increasing the knowledge on how the heat transfer process is affected by various hardware and operational parameters in the engine. The engines concerned are both conventional die

Mycorrhiza and carbon flow to the soil

The current extent of knowledge on the supply of carbon compounds to mycorrhizal roots and mycelia, and their subsequent distribution and cycling within the soil ecosystem is reviewed. The carbon requirements of different mycorrhizal fungi are discussed and carbon transfer from host root tissue to the fungal biomass is considered in relation to available information on the amounts and types of com

Studies of New Bioactive Fungal Metabolites

A number of bioactive natural products have by chromatographic techniques been isolated from extracts of various fungi, and their structures have been determined by spectroscopic and chemical methods. In the screening of fungal extracts for the inhibition of the binding of various ligands to CNS receptors in rat striatal membrane preparations in vitro, bioassay-guided fractionation of extracts of

Comparison Between Measured and Computed Structural Response of Some Reinforced Concrete Colums in Fire

This paper is the first result of recently commenced cooperation in structural fire engineering research between the Lund Institute of Technology, and the Fire Research Department of the Technical University of Brunswick. The goal of the project is to develop improved calculation methods based on more reliable behaviour models of concrete and steel. Fox this reason tests on columns carried out at

Studies of Electrocatalytic Reactions of NADH at Mediator Modified Electrodes and of H2O2 at Peroxidase Modified Electrodes

Popular Abstract in Swedish Många biokemiska reaktioner har höga aktiveringsenergier och utan de katalyserande enzymerna skulle de flesta ämnes- omsättningsprocesser fortskrida alldeles för långsamt för att uppehålla liv. Enzymer kallas ofta för biokatalysatorer eftersom de verkar katalytiskt, dvs påskyndar kemiska reaktioner utan att själva förändras. De finns i en enorm variation eftersom vart oThis thesis addresses: (1) studies of direct and mediated electron transfer and kinetics of peroxidases on electrodes and the development of amperometric peroxidase-based biosenors, (2) electrochemical and kinetic studies of NADH oxidation at mediator modified electrodes. The direct and mediated electron transfer of horseradish and tobacco peroxidase were investigated on graphite electrodes by us

Expression and localization of extracellular matrix proteins in rat skeletal development

Several novel matrix molecules of cartilage and bone have recently been identified and characterized. Studies of the maturation of the femoral head give clues as to the function of the novel matrix proteins. We have studied the expression and localization of two cartilage proteins: COMP, chondroadherin (CHAD), and two bone proteins: BSP and osteoadheirn (OSAD). COMP was localized throughout cartil