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Molecular pathologies can be targeted using lipid nanoparticles carrying therapeutic RNA. Extrahepatic delivery remains a major bottleneck, however, small lipid nanoparticles could allow targeting of deeper tissue layers, low vascularized tumors and the lymph nodes, improving the range of druggable cell types and diseases. Lipid nanoparticle size as a tunable parameter influencing therapeutic effi

This thesis examines the interaction between capital markets, commercial banks, and investment banks, by further developing an existing model of financial system architecture. The development consists of adding the distinction between commercial and investment banks to the bank sector. Previous literature has debated whether the development of the bank sector and capital markets is mutually benefi

This thesis examines which fiscal instruments are considered as Covered Taxes under the GloBE Model Rules particularly in the Oil and Gas sector. The countries used for the examination are Brazil and Nigeria as both have a huge oil and gas sector. While Brazil has adopted a Qualified Domestic Top-up Tax, Nigeria has abstained against the Pillar Two framework. The main research question explor

This thesis aims at understanding, through simulation, how the cosmic muon flux will look like in LDMX’s HCal and to use the characteristics of minimally ionizing muons to set up a method for scintillator bar calibration. LDMX’s HCal is a sampling calorimeter with scintillator bars as the active material. Cosmic muons enter the HCal from different angles, and thereby deposit different amounts of e

This paper addresses sustainability clauses in the European Union’s (EU) free trade agreements (FTAs) and examines their role in integrating environmental, social, and economic objectives within international trade. Against the backdrop of global sustainability agendas – namely Agenda 2030 and the European Green Deal – the study investigates how these contractual provisions are designed to support

This study presents a comprehensive analysis of the spatiotemporal dynamics of water quality in Lake Bolmen, southern Sweden, based on high-resolution monitoring data (2022–2024) from five regions. Key parameters—including temperature, dissolved oxygen, pH, turbidity, electrical conductivity, oxidation-reduction potential, and chlorophyll fluorescence—were assessed using data analysis method inclu

Choosing the right discrete-event simulation (DES) software is a challenging and important task. Given the announcement that sales and support of AFRY’s primary DES software, AutoMod, will be discontinued by December 31, 2026, and the lack of a recent review of the current market offerings, it is a essential for AFRY to explore new alternatives. The aim of the thesis is to help AFRY analyze and se

This thesis explores the electrification of the public transport sector in Kathmandu Valley using the Multi-Level Perspective framework and a lens based on Political Economy. It analyses how government bodies, the private sector, civil society, development organisations, and academia influence transition dynamics. Drawing on semi-structured interviews and fieldwork, it identifies drivers such as a

Under de senaste decennierna har vårdsystem i allt högre grad formats av styrmodeller inriktade på effektivitet, ofta påverkade av marknadsbaserade ideal. Denna studie undersöker hur sjuksköterskor upplever konsekvenserna av sådana reformer, särskilt i relation till deras arbetsvillkor och deras upplevda kvalitet på patientvården, samt hur dessa upplevelser skiljer sig mellan offentlig och privat

This thesis project, initiated by Thule, aimed to develop a concept for a foldable roof box. The goal was to create a solution that is easier to handle and store than traditional roof boxes, which are often perceived as bulky and difficult to manage when not in use. The project followed a design process based on the Double Diamond model, Human-Centered Design, and Thule’s internal development pro

This thesis analyses how rights-based youth climate groups can sustain their interventions during political transitions, using the YES4ECO project in Bangladesh as a case study. The youth-led project in the climate-vulnerable districts of Bangladesh faced disruption following the uprising in July 2024, as it destabilised the local government structures. The study draws on 29 key informant intervie

Följande uppsats behandlar rapporteringen av prostitution i Dagens Nyheter under perioden 1994-2024. Syftet återfinns i hur rapporteringen tagit sig uttryck under perioden, med ett något speciellt fokus riktat mot prostitutionens aktörer. Materialet har valts ut med hjälp av Retriever Research och undersökts med utgångspunkt i en kvalitativ innehållsanalytisk ansats. Utifrån feministisk teori och

As China's aging process accelerates, it is becoming increasingly difficult for existing urban infrastructures to meet the needs of older adults in terms of daily mobility and social participation. This paper examines how urban infrastructure in China facilitates or constrains the daily lives of older adults by understanding the perspectives of family caregivers. Based on data from semi-struct

The advent of Lethal Autonomous Weapons Systems (LAWS) introduces transformative, yet deeply problematic, complexities into modern warfare, particularly concerning the attribution of criminal responsibility under international criminal law. This thesis confronts the critical challenges these systems pose to the dolus specialis, the specific intent to destroy, requirement for the crime of genocide.

In this study, we focused on highlighting the importance of relationships between the professional and the client in HVB. The aim was to investigate how the relationship could contribute to preventing recidivism in adolescents and young adults. The study was qualitative and based on our semi-structured interviews to get in-depth reflections and experiences of their work. We used a purposive sampli

This thesis investigates the existence of a green bond premium, or greenium, in the European corporate bond market. It examines how ESG disagreements affect this premium. By utilising secondary market data for 515 green bonds and 2.325 conventional bonds issued between 2018 and 2025, a matching methodology based on Zerbib (2019) is employed to isolate the yield differential attributed to the green

This thesis explores how public spaces are emotionally and socially experienced through introducing the concept of affective publicness, which is a framework for understanding the emotional and relational dynamics that shape urban public spaces. Departing from the theoretical frame of emotional geography and affective urbanism, the research investigates how affective publicness is felt and shaped

Family reunification lies at the intersection of humanitarian values, national identity, and gender politics, making it one of the most complex and debated areas of immigration policy. This thesis examines how nationalism and gender inequality, individually and together, shape family reunification policies across 27 European countries. Grounded in the theoretical frameworks of femonationalism, int

Denna uppsats undersöker hur kapitalmarknadsstrukturen i Europeiska unionen påverkar startups möjlighet till finansiering, med jämförelser mot Sverige och USA. Studien visar att EU:s kapitalmarknader präglas av fragmentering och institutionella skillnader, vilket hämmar tillgången till riskkapital och gränsöverskridande investeringar. Genom en komparativ analys av Sverige och USA identifieras faktThis thesis examines how the structure of capital markets in the European Union affects startups’ access to financing, with comparisons to Sweden and the United States. The study shows that the EU's capital markets are characterized by fragmentation and institutional differences, which hinder access to venture capital and cross-border investments. Through a comparative analysis of Sweden and t

Emulsifiers can influence fat crystallization through multiple mechanisms: by promoting or in-hibiting nucleation, modifying polymorphic transitions, or enhancing oil-binding capacity. In collaboration with Palsgaard A/S, this thesis aimed to evaluate the functional impact of selected emulsifiers from their portfolio on the thermal and textural stability of fat-based biscuit cream fillings. The go