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Entrepreneurship as a Career : An investigation into the pre-entrepreneurship antecedents and post-entrepreneurship outcomes among the Science and Technology Labor Force (STLF) in Sweden

This dissertation provides a career perspective on entrepreneurship based on the research question: “How do organizational bureaucracy and relative income affect the career choice of entrepreneurship among employees from the science and technology labor force (STLF); and what are the career outcomes in terms of returns during, and post entrepreneurship on re-entry into paid employment?” More speci

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

BACKGROUND: The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by host genetic variation. In the framework of the Milieu Intérieur Consortium, a total of 1000 healthy individuals of western European ancestry, with a 1:1 sex ratio and evenly stratified across five decades of life (age 20-69), w

The Gaia-ESO survey: Calibrating a relationship between age and the [C/N] abundance ratio with open clusters?

Context. In the era of large high-resolution spectroscopic surveys such as Gaia-ESO and APOGEE, high-quality spectra can contribute to our understanding of the Galactic chemical evolution by providing abundances of elements that belong to the different nucleosynthesis channels, and also by providing constraints to one of the most elusive astrophysical quantities: stellar age. Aims. Some abundance

Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators

Herein we describe the discovery of ACP-105 (1), a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. Compound 1 was developed from a series of compounds found in a HTS screen using the receptor selection and amplification technology (R-SAT). In vivo, 1 improved anabolic parameters in a 2-week chro

Growth of bacteria in the rhizoplane and the rhizosphere of rape seedlings

The growth of 10 isolates of rhizosphere bacteria was compared in the rhizoplane (RP), rhizosphere (RS) and non-rhizosphere soil of a model system with rape seedlings growing in sterile sand. The colonization of the RP differed little among isolates. However, the bacterial isolates differed according to their degree of dependence on the root for growth, as judged by RS:RP and plant:non-plant ratio

Model system for studies of microbial dynamics at exuding surfaces such as the rhizosphere.

An autoclavable all-glass system for studying microbial dynamics at permeable surfaces is described. Standard hydrophobic or hydrophilic membranes (46-mm diameter) of various pore sizes were supported on a glass frit through which nutrient solutions were pumped by a peristaltic pump. The pump provided a precisely controlled flow at speeds of 0.5 to 500 ml of defined or natural cell exudates per h,

Precision and sensitivity of the measurement of 15 N enrichment in D-alanine from bacterial cell walls using positive/negative ion mass spectrometry

Sensitive detection of cellular components from specific groups of microbes can be utilized as 'signatures' in the examination of microbial consortia from soils, sediments or biofilms. Utilizing capillary gas chromatography/mass spectrometry and stereospecific derivatizing agents, D-alanine, a component localized in the prokaryotic (bacteria) cell wall, can be detected reproducibly. Enrichments o

Detection of joint pathology by magnetic resonance imaging in patients with early rheumatoid arthritis

Magnetic resonance imaging (MRI) permits the visualization of anatomical structures not appreciated by conventional radiographic imaging, and may assess inflammatory disease and its progression with greater sensitivity than conventional radiography. In this study of 30 patients with early rheumatoid arthritis (RA), which could be considered as a pilot study because of the relatively small number o

Kultur och värdegrundsarbete ur ett tillitsperspektiv

Med tillitsbaserad styrning och ledning vill vi öka möjligheten för medarbetare att använda sitt professionella omdöme. Detta utrymme påverkas emellertid inte bara av styrningen, utan även av kulturen i organisationen och i sektorn i stort. För att bidra till en god förvaltningskultur bedriver idag de flesta offentliga organisationer ett strukturerat värdegrundsarbete. Många myndigheter väljer att

Uppföljning ur ett tillitsperspektiv

Uppföljning är nödvändig i alla verksamheter. Det finns emellertid mycket som tyder på att vi lägger alltför stora resurser på uppföljning och att vi dessutom följer upp på fel sätt. I denna rapport diskuterar jag hur uppföljning kan utformas för att bidra till ökad tillit i allmänhet och ökad tillit till de medborgarnära professionerna i synnerhet, inom ramen för offentliga organisationer. Jag sl

Striving for democracy in the nordic context: possibilities for change through innovative cases of activist music practices

In this roundtable we will present three cases of activist music education, in other words innovative and inclusive practices of music education initiated by courageous institutional leaders and teachers in the Finnish and Swedish context. By activism we mean professional thinking and action that strives toward new ways of making change inside and outside educational institutions through four char

Gender identification in Chinese names

In this paper we discuss a number of factors that bear on the question if a Chinese given name is more likely to refer to a female or a male. In some cases this can be determined (with some degree of confidence) – in others it cannot. We identify the relevant factors as 1) gender-identifying characters or radicals; 2) sound symbolism and 3) reduplication. We consider the relations between these fa

Conceptualising and situating overtourism in urban contexts

One of the most important trends in contemporary tourism is the increase in urban tourism, both in absolute and in relative terms. In some destinations, e.g. Barcelona, the pressure from tourism on local resources such as housing and urban space has reached a point where we begin to speak about overtourism. The development of overtourism is related to decreasing relative costs of travel, e.g. low-

Discordant amyloid-β PET and CSF biomarkers and its clinical consequences

Background: In vivo, high cerebral amyloid-β load has been associated with (i) reduced concentrations of Aβ42 in cerebrospinal fluid and (ii) increased retention using amyloid-β positron emission tomography. Although these two amyloid-β biomarkers generally show good correspondence, ~ 10-20% of cases have discordant results. To assess the consequences of having discordant amyloid-β PET and CSF bio

Complete regioselective addition of grignard reagents to pyrazine N-oxides, toward an efficient enantioselective synthesis of substituted piperazines

(Figure presented) A conceptually new one-pot strategy for the synthesis of protected substituted piperazines via the addition of Grignard reagents to pyrazine N-oxides is presented. This strategy is high yielding (33-91% over three steps), step-efficient, and fast. The synthesized N,N-diprotected piperazines are convenient to handle and allow for orthogonal deprotection at either nitrogen for sel