Several processes in the cell, such as gene regulation, start when key proteins recognize and bind to short DNA sequences. However, as these sequences can be hundreds of million times shorter than the genome, they are hard to find by simple diffusion: diffusion-limited association rates may underestimate in vitro measurements up to several orders of magnitude. Moreover, the rates increase if the D

Ab initio simulations of a range of interferometric experiments are used to identify a strong dependence on multiphoton phase shifts in above-threshold ionization (ATI). A simple rule of thumb for interaction phase shifts is derived to explain both the conservation of photoelectron yield and its absolute CEP dependence. For instance, it is found that interferometric (ATI) experiments are shifted b

We provide a detailed map of the ages and metallicities of turn-off stars in the Milky Way disc based on data from GALAH DR3 and Gaia EDR3. From this map, we identify previously undetected features in the age-metallicity distribution of disc stars and interpret these results as indicating a three-phase formation history of the Milky Way. In the first phase, inner disc stars form along a single age

Since the advent of Gaia astrometry, it is possible to identify massive accreted systems within the Galaxy through their unique dynamical signatures. One such system, Gaia-Sausage-Enceladus (GSE), appears to be an early 'building block' given its virial mass >1010M⊙ at infall (z ~ 1-3). In order to separate the progenitor population from the background stars, we investigate its chemical properties

Survival after blood or marrow transplantation (BMT) for inborn errors of metabolism (IEM) is excellent; however, the burden of morbidity in long-term survivors of BMT for IEM remains understudied. This study examined the risk of chronic health conditions (CHC) in ≥2-year survivors of allogeneic BMT for IEM performed between 1974 and 2014 using the BMT Survivor Study. In this retrospective cohort

This paper documents the seventeenth data release (DR17) from the Sloan Digital Sky Surveys; the fifth and final release from the fourth phase (SDSS-IV). DR17 contains the complete release of the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, which reached its goal of surveying over 10,000 nearby galaxies. The complete release of the MaNGA Stellar Library (MaStar) accompanies

Introduction: The screening program for cervical cancer in Sweden recommends the use of primary human papillomavirus (HPV) screening for women aged ≥30 to 65 years. Co-testing with both HPV analysis and cytology is recommended at the first screening after the age of 40 years. To fulfil co-testing, all screened women aged 40–42 years within the region of Skåne were co-tested. The aim of the audit w

We present the first large-scale study that demonstrates how ages can be determined for large samples of stars through Galactic chemical evolution. Previous studies found that the elemental abundances of a star correlate directly with its age and metallicity. Using this knowledge, we derive ages for 214 577 stars in GALAH DR3 using only overall metallicities and chemical abundances. Stellar ages a

Syftet med denna studie är att belysa hur kommunal och privat hemtjänstpersonal resonerar om varandras verksamheter i utförandet av biståndsbedömda insatser inom äldreomsorgen. Studien är baserad på 28 öppna, semistrukturerade intervjuer med hemtjänstpersonal i kommuner som infört kundval.Resultatet visar att hemtjänstpersonalen, verksamhetsformerna emellan, utvecklar både allianser och polariseri