Användning av cookies

Lunds universitet använder cookies för att se till att webbplatsen fungerar korrekt och för att förbättra din upplevelse.

Läs mer i vår cookiepolicy

Sökresultat

Filtrera

Nollställ filter

Filtyp

Din sökning på "*" gav 534723 sökträffar

Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila

During autophagy, phagophores capture portions of cytoplasm and form double-membrane autophagosomes to deliver cargo for lysosomal degradation. How autophagosomes gain competence to fuse with late endosomes and lysosomes is not known. In this paper, we show that Syntaxin17 is recruited to the outer membrane of autophagosomes to mediate fusion through its interactions with ubisnap (SNAP-29) and VAM

Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila

BACKGROUND: Two pathways are responsible for the majority of regulated protein catabolism in eukaryotic cells: the ubiquitin-proteasome system (UPS) and lysosomal self-degradation through autophagy. Both processes are necessary for cellular homeostasis by ensuring continuous turnover and quality control of most intracellular proteins. Recent studies established that both UPS and autophagy are capa

Optimizing DRX for Video delivery over LTE: Utilizing Channel Prediction and In-network caching

We jointly optimize Discontinuous Reception (DRX) cycle length and LTE scheduling to minimize mobile devices' energy usage for video delivery, utilising the now well-established potential to predict future channel conditions in cellular networks. Employing in-network caching, we set a strict buffer constraint which provides zero buffer underflow to improve Quality of Experience. Our study provides

Creativity and the evolvement of culture. The altering capacity of art works, paper presentation, Lisbon, 26-29 June.

Title:Creativity and the evolvement of culture. The altering capacity of art works.Creativity, in the sense finding original solutions to life world problems, can be seen as the principal force of cognitive and communicational genesis, such as when new verbal language elements occur (Heine/Kuteva 2007). Creativity has been defined as the original act that not only makes a radical “revision of a co