The NMDA receptor complex represents a key molecular element in the pathogenesis of long-term synaptic changes and motor abnormalities in Parkinson's disease (PD). Here we show that NMDA receptor 1 (NR1) subunit and postsynaptic density (PSD)-95 protein levels are selectively reduced in the PSD of dopamine (DA)-denervated striata. These effects are accompanied by an increase in striatal levels of

We consider the capacity of multiple-input multiple-output systems with. reduced complexity. One link-end uses all available antennas, while the other chooses the L out of N antennas that maximize capacity. We derive an upper bound on the capacity that can be expressed as the sum of the logarithms of ordered chi-square-distributed variables. This bound is then evaluated analytically and compared t

The distribution of necks in slender structures obtained using high rate deformation often differs from the distribution obtained under quasistatic conditions. Initial thickness imperfections are often used to initiate necking at certain locations along a specimen surface. At sufficiently large deformation rates, necks may develop at sites that correlate weakly or not at all with the sites of the

Temporal trend studies of PCBs and DDTs in two annually laminated sediment cores from the offshore NW Baltic proper and the Stockholm archipelago demonstrate that studies of laminated sediments are useful tools for detecting time trends of HOCs. The concentration trends of PCBs and DDTs, on a dry weight basis, from the two cores show quite large similarities to trends reported in pelagic biota fro

OBJECTIVE: To evaluate the long-term outcome of patients treated in the surgical intensive care unit (SICU) for abdominal sepsis. DESIGN: Retrospective study. SETTING: University hospital, Sweden. SUBJECTS: 210 consecutive patients treated for abdominal sepsis in the SICU at Lund University Hospital during the period January 1983 to December 1995. MAIN OUTCOME MEASURES: Background information, mor

The high solubility in acidic solutions of N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl-diphenylphosphine (N3P) make it a suitable candidate for study and comparison to the more commonly studied trisulfonated triphenylphosphine (TPPTS) ligand in the palladium catalysed aqueous hydrocarboxylation reaction. The catalyst employing N3P shows an inverted regioselectivity compared to the TPPTS

The review and Paper I present applications of economics to the use of alcohol. The review considers the demand for alcohol. The first paper also considers taxes and other alcohol policy measures, social costs and economic evaluations. In Paper II, an Almost Ideal Demand System Model is used for the study of the demand for alcoholic beverages in Sweden during the years 1985-1995. The results indi

To investigate the morphological basis for olfactory reception in the carrot psyllid (Trioza apicalis) we used scanning and transmission electron microscopy. Our study reveals a very sparse sensillar setup. We identify and describe several different types of single-walled sensilla likely to have an olfactory function, as well as mechanosensory hairs and intracuticular sensilla. A T. apicalis anten

Endothelins are recently discovered peptides that cause vasoconstriction and bronchoconstriction. The significance to the mucociliary system of endothelins (ET) 1, 2 and 3 in upper as well as lower airways has not yet been clarified. Effects of these active peptides were investigated, combining both in vitro and in vivo rabbit models of mucociliary activity from the maxillary sinus and the trachea

Storlekens betydelse i en hämningslös värld. Det storslagna och det sublima. Kommentar och referens till Erling Fossen, Rem Koolhaas, Edmund Burke, Immanuel Kant, Luce Irigaray och Kenneth Frampton.

Background and Purpose - Regular endurance exercise has been shown to reduce the age-related increase in arterial stiffness that is thought to contribute to cardiovascular risk. The aim of this study was to evaluate the influence of age and habitual physical activity on carotid artery wall thickness and stiffness in a population of young to middle-age subjects at low cardiovascular risk. Methods -

The human-specific bacterial pathogen Neisseria meningitidis is a major cause of sepsis and/or meningitis. The pili of N. meningitidis interact with CD46, a human cell-surface protein involved in regulation of complement activation. Transgenic mice expressing human CD46 were susceptible to meningococcal disease, because bacteria crossed the blood-brain barrier in these mice. Development of disease

Presents an approach to improved performance and flexibility in industrial robotics by means of sensor integration and feedback control in task-level programming and task execution. Also presents feasibility studies in support of the ideas. Discusses some solutions to the problem using six degrees of freedom force control together with the ABB S4CPlus system as an illustrative example. Consider va

We report on a study of singlet-singlet annihilation kinetics in a series of Zn(II)-porphyrin-appended dendrimers, where the energy transfer efficiency is significantly improved by extending the molecular chain that connects the light-harvesting chromophores to the dendrimeric backbone with one additional carbon. For the largest dendrimer having 64 Zn(II)-porphyrins, only 10% of the excitation int

In 11 healthy volunteers, the normal kinematics of the tibiofibular syndesmosis of the ankle during weight bearing and external rotation stress were compared to a nonweight-bearing neutral position by radiostereometry. We found very small rotations and displacements in this "normal" group, which indicated that the fibula is closely attached to the tibia, thereby preventing larger movements at the