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Local stakeholders' acceptance of model-generated data used as a communication tool in water management: The Ronnea study

The objective of this study was to increase the knowledge of local stakeholders' acceptance of model-generated data when used as a communication tool in water quality management. The Ronnea catchment in the southwest of Sweden was chosen as the study area. The results indicate the model-generated data served as a uniting factor. Simultaneously, the stakeholders were concerned with presented data,

Mechanosensory properties of the mouthpart setae of the European shore crab Carcinus maenas

In decapod crustaceans, the largest density and diversity of sensilla, referred to as setae, is in general found on the mouthparts, but little is known about their sensory properties and thereby their functions. Here data are presented from mechanoreceptors from the two largest mouthparts, maxilliped 2 and 3, of the European shore crab Carcinus maenas. The mechanoreceptors were found to respond to

Synthesis and Reactivity Studies of Model Complexes for Molybdopterin-Dependent Enzymes

The molybdenum cofactor (Moco)-containing enzymes are divided into three classes that are named after prototypical members of each family, viz. sulfite oxidase, DMSO reductase and xanthine oxidase. Functional or structural models have been prepared for these three prototypical enzymes: (i) The complex [MoO2(mnt)2]2− (mnt2−=1,2-dicyanoethylenedithiolate) has been found to be able to oxidize hydroge

Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells.

It has been previously suggested that leukotriene-induced Ca2+ signalling is mediated through a Rho-dependent process, but neither direct activation of Rho nor a mechanism underlying such signalling has been reported. Accordingly, we used the Rhotekin binding assay to assess RhoA activation in intestinal epithelial cells and observed that RhoA was activated by leukotriene D4 (LTD4). We also found

Packaging of a flexible polyelectrolyte inside a viral capsid: Effect of salt concentration and salt valence

The effect of salt on the location and structure of a flexible polyelectrolyte confined inside a viral capsid and the Donnan equilibrium of the salt across the capsid have been examined using a coarse-grained model solved by Monte Carlo simulations. The polyelectrolyte was represented by a linear jointed chain of charged beads, and the capsid was represented by a spherical shell with embedded char

Monitoring patients treated with anti-TNF- biopharmaceuticals: assessing serum infliximab and anti-infliximab antibodies

Objectives. Infliximab is an anti-tumour necrosis factor-alpha (TNF-alpha) mousehuman IgG1/k antibody used to treat patients with rheumatoid arthritis (RA) and other inflammatory diseases. Unfortunately, response failure and side-effects due to immunogenicity of the drug are not rare. In this study, we have compared different methods of assessing drug levels and anti-infliximab antibodies (Abs) an

Influence of the Velocity Near the Spark Plug on Early Flame Development

The objective of this paper is to investigate how the velocity and turbulence within different locations close to the spark plug influence the combustion at individual cycles in a SI-engine. 2-D cycle-resolved laser doppler velocimetry (LDV) measurements have been done both inside the spark gap and around the spark tip to extract velocity information. The pressure in the cylinder was measured with

Bcg vaccination as a cause of multifocal osteomyelitis in a 12-year-old girl

A 12-year-old girl with multifocal skeletal sclerosis has been investigated. She was BCG vaccinated at birth and developed regional lymphadenitis in her left groin at two months of age. She was healthy until approximately 10 years of age, after which deficient height and weight gain occurred. BCG-itis was diagnosed in skeleton lesions. No evidence of immunodeficiency was found in the patient. Afte

Six-quasiparticle isomer in Nd-140

A search for isomeric states was performed in the nucleus Nd-140(60)80 using in-beam gamma-ray spectroscopy and the Te-126(O-18,4n) reaction. Prompt and delayed gamma-ray coincidences were measured with the AFRODITE spectrometer using the pulsed beam delivered by the Separated Sector Cyclotron of iThemba LABS. One new isomer was identified, with spin-parity I-pi=20(+) and lifetime T-1/2 >= 400 ns,

Technology demonstration solar telescope

The conceptual design of the Large Earth-based Solar Telescope (LEST)has evolved through the years. In 1995-97 it was discussed whether atechnology demonstration telescope could be built at a lower cost thanthe LEST originally proposed. In 1997, a de-scoped LEST design, theso-called "Mini-LEST", was conceived and proposed to the LEST community.The telescope has an innovative design with a small fi