Background: Adults with complex congenital heart disease (CHD) have reduced aerobic capacity and impaired muscle function. We therefore hypothesized that patients have a lower skeletal muscle mass and higher fat mass than controls. Methods: Body composition was examined with full body Dual-Energy x-ray Absorptiometry (DXA) in 73 patients with complex CHD (mean age 35.8 ± 14.3, women n = 22) and 73

This article contributes to the emerging literature on possibilities to disseminate agonistic narratives in seemingly deadlocked conflict settings. In this context, conflict parties’ existence is often perceived as being under threat, which makes it demanding to question the current societal order. However, even in the most protracted of conflicts, narratives exist that challenge concurring undersThis article contributes to the emerging literature on possibilities to disseminate agonistic narratives in seemingly deadlocked conflict settings. In this context, conflict parties’ existence is often perceived as being under threat, which makes it demanding to question the current societal order. However, even in the most protracted of conflicts, narratives exist that challenge concurring unders

Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estim

Increased attention has been paid to circadian patterns and how predisposition to metabolic disorders can be affected by meal timing. Currently, it is not clear which role can be attributed to the foods selected at meals. On a cross-sectional sub-cohort study (815 adults) within the EPIC-Potsdam study we investigated whether the same foods (vegetables, fruits, refined grains, whole grains, red and

This paper uses matched employer-employee data set for Sweden to study the relationship between firm age and wages, systematically addressing a variety of possible explanations for observing a firm age-wage effect. Results show considerable heterogeneity across years, along segments of the firm age distribution and across industries. For 1995, a positive relationship is found between firm age and

The number of the X chromosome–linked genes has been previously suggested to influence immune responses and the development of autoimmune diseases. In the present study, we aimed at evaluating the level of expression of CD40L (an X-linked gene involved in adaptive immunity) and TLR7 (an X-linked gene involved in innate immunity) in a variety of different karyotypes. Those included males, females a

Seven large European Union (EU)–funded epilepsy-related research projects joined forces in May 2018 in Brussels, Belgium, in a unique community building event—the epiXchange conference. During this conference, 170 investigators from the projects DESIRE, EpimiRNA, EPISTOP, EpiTarget, EpiXchange, and EpiPGX as well as the European Reference Network EpiCARE, met up with key stakeholders including rep

There is evidence that the destruction of the pancreatic B cell in insulin-dependent diabetes mellitus is due to autoimmune reactions. Transplantation of islet cell tissue might then provoke 'reimmunization', and this could presumably lead to destruction of the transplanted B cells. The authors have looked for signs of recurrence of autoimmunity following pancreatic transplantation.

Migraine is a common neurological disorder that afflicts up to 15% of the adult population in most countries, with predominance in females. It is characterized by episodic, often disabling headache, photophobia and phonophobia, autonomic symptoms (nausea and vomiting), and in a subgroup an aura in the beginning of the attack. Although still debated, many researchers consider migraine to be a disor

At and before onset, most insulin-dependent diabetics (IDDM) have islet GAD65 autoantibodies (GAD65Ab). Since IDDM also occurs in older patients where non-insulin-dependent diabetes is common, we studied GAD65Ab at onset to classify diabetes type. Our quantitative immunoprecipitation assay uses recombinant human islet GAD65 stably expressed in hamster fibroblasts. Electrophoretic mobility was iden

Reactivity controlled compression ignition (RCCI) engines suffer from low thermal efficiency at low loads due to the high hydrocarbon and carbon monoxide emissions. Correspondingly, a direct dual fuel stratification (DDFS) combustion mode is investigated by directly injecting methanol and diesel into cylinder. Multi-objective optimization and detailed comparison are first conducted for the two eng

The somatotype is a useful method in the analysis of body morphology but no study has identified genetic variants associated with its components. The aim of this study is o replicate the association of 21 SNPs with obesity and to explore their association with the somatotype components, in a sample from the Basque Country (Spain). A case-control study was performed in 472 adults from 18 to 79 year