Background: NOTCH1 PEST domain mutations in chronic lymphocytic leukemia have recently been shown to be of prognostic relevance. Both NOTCH1 and NOTCH2 are constitutively activated in B-cell CLL but not expressed in normal B cells and may be involved in survival and resistance to apoptosis in CLL. We screened for mutations in different parts of both NOTCH1 and NOTCH2 genes and related the changes

Sommaren 2013 etablerades den svenska supply chain-panelen av forskare från Institutionen för teknisk ekonomi och logistik vid Lunds universitet. Panelen består av personer som alla arbetar på ledningsnivå med SC-frågor på olika företag som är verksamma i Sverige. Medlemmarna representerar en god blandning av olika typer av företag inom olika branscher och har gått med på att svara på fyra (4) enk

Since Durkheim’s seminal work over a century ago, research has repeatedly shown that individuals with higher levels of social integration, social networks and social support have better health status. However, the recent introduction of a contextual phenomenon known as social capital to the field of public health has sparked lively debate as to how it may also influence the health of individuals,

Regional climate models (RCMs) are used for forecasting future climate including precipitation characteristics. Performances of five different RCMs for predicting the precipitation characteristics for Gothenburg, Sweden were evaluated against the daily observed precipitation over the period 1961 to 2009. Statistical analysis was done on annual, monthly, multi-daily, and daily data. The statistical

An alternative concept for calibrating spectral image intensity ratios is described, which provides simple, but effective means of compensation for systematic errors, caused by nonlinearities in signal detection. The method relies on image segmentation by means of signal thresholds, where pixels are organized into different subgroups according to their corresponding signal count value. Instead of

Generalized Frequency Division Multiplexing (GFDM) is a recent multi carrier modulation technique that can provide low out-of-band radiation, which makes it an attractive choice for the PHY layer of cognitive radios operating in fragmented TV white spaces. Primary, incumbent signals can now be protected with a geo-location database query mechanism. Even then, sensing opportunistic users (OU) opera

ZnO nanowires were grown on Ag wire with a diameter of similar to 250 mu m and used in an electrochemical sensor. The enzyme glucose oxidase (GOD) was immobilized on the ZnO nanowires, and the Ag wire was connected directly to the gate of a MOSFET. Upon exposure to glucose (1-100 mu M), the electrochemical response from the GOD induced a stable measurable voltage change on the gate leading to a st

Popular Abstract in Swedish Kontrakt som handlas på de internationella finans- och råvarumarknaderna är förenade med komplexa riskstrukturer. Denna avhandling behandlar två specifika typer av risk; marknadsrisk och kreditrisk. Det första kapitlet i avhandlingen undersöker marknadsrisker på den Nordiska elmarknaden. Vi utför in-sample och out-of-sample backtesting av en VaR-modell baserad på GARCContracts traded on international financial and commodity markets are associated with complex risk structures. In this dissertation we are concerned with two specific types of risks; market risks and credit risks. The first chapter investigates market risks in the context of the Nordic electricity market. The paper performs in- and out-of-sample backtesting of a VaR model based on GARCH volatili

To define the clinical presentation of aerococcal infective endocarditis (IE) and the prevalence of synergy between penicillin and gentamicin on aerococcal isolates.

Popular Abstract in English Mobile communication systems are now evolving towards the fifth generation (5G). In the near future, we expect an explosive increase in the number of connected devices, such as phones, tablets, wearable accessories, sensors, connected vehicles and so on. We can imagine that much higher data rates than in today's 4G systems are required. Sounds like the future of communiMobile communications are now evolving towards the fifth generation (5G). In the near future, we expect an explosive increase in the number of connected devices, such as phones, tablets, sensors, connected vehicles and so on. Much higher data rates than in today's 4G systems are required. In the 5G visions, better coverage in remote regions is also included, aiming for bringing the current "4 bill

Automation, in terms of systems such as adaptive/active cruise control (ACC) or collision warning systems, is increasingly becoming a part of everyday driving. These systems are not perfect though, and the driver has to be prepared to reclaim control in situations very similar to those the system easily handles by itself. This paper uses a questionnaire answered by 130 ACC users to discuss future

Recension av Anders Hammarlund, En bön för moderniteten. Kultur och politik i Abraham Baers värld.