OBJECTIVES: Early onset ataxia (EOA) concerns a heterogeneous disease group, often presenting with other comorbid phenotypes such as myoclonus and epilepsy. Due to genetic and phenotypic heterogeneity, it can be difficult to identify the underlying gene defect from the clinical symptoms. The pathological mechanisms underlying comorbid EOA phenotypes remain largely unknown. The aim of this study is

According to the proposal for a minimum reporting guideline for an eye tracking study by Holmqvist et al. (2022), the accuracy (in degrees) of eye tracking data should be reported. Currently, there is no easy way to determine accuracy for wearable eye tracking recordings. To enable determining the accuracy quickly and easily, we have produced a simple validation procedure using a printable poster

To differentiate between medical malpractice and expected, but rare, medical complication in a medicolegal autopsy context is often difficult. Such an assessment requires knowledge about the clinical practice associated with the procedure at hand, and that findings of the autopsy, including medical relevant information such as patient chart, radiological imaging, and statements from witnesses abou

Sustainability has emerged as a critical aspect of business operations globally, encompassing environmental impact, social responsibility, and governance factors. With its ability to allocate financial resources, the banking sector plays a unique role in achieving global sustainability goals. This makes it vital for banks to prioritize sustainability and embed it as a core value due to customer de

The aim of this study was to explore how personal stories describe social norms when speaking of sexuality. Data was collected through a qualitative thematic analysis of the book Flickan och skammen written by Katarina Wennstam. The book contains six personal stories of women who have been exposed to sexual violence at some point in their life. The results of the study show that social norms have

I Skellefteå sker i dagsläget en omfattande samhällsomvandling till följd av nya befolkningsmål och etableringen av bilbatterifabriken Northvolt. Det ställs därför höga krav på den sociala infrastrukturen med avseende på intensiteten i omvandlingen, något som väcker frågor om stadens förmåga att utvecklas socialt hållbart och omvandlingens påverkan på lokalbefolkningen. Syftet med uppsatsen ämnar

This study explores the dynamics between the student union and programme associations at Lund University's Faculty of Social Sciences. Examining the perspectives of programme association representatives on the union and themselves, it investigates the union's challenges, the political tensions between the organisations and the way in which they may serve as a microcosm reflecting broader s

The aim of this thesis is to examine the professionals’ views on young offenders and responsibility for the target group. We have chosen to interview social workers who work within the public sector and have direct contact with young offenders. Discursive psychology was used to analyse our empirical material in order to highlight the interpretative repertoires permeating through the professionals’

The aim of this study was to explore how Swedish social workers were affected by the disinformation campaign claiming that social services take children. The study explored how social workers were affected by this in their work revolving around meetings with clients and assessments. We used a qualitative method with semi-structured interviews. The result is based on interviews with seven Swedish s

Streptococcus pyogenes causes a multitude of local and systemic infections, the most common being pharyngitis in children. Recurrent pharyngeal infections are common and are thought to be due to the re-emergence of intracellular GAS upon completion of antibiotic treatment. The role of colonizing biofilm bacteria in this process is not fully clear. Here, live respiratory epithelial cells were inoc

Vascular dysfunction is a hallmark of systemic inflammatory responses such as bacterial sepsis. The luminal surface of the blood vessels is coated with a dense layer of glycans and proteoglycans, collectively known as the glycocalyx. Surface associated glycoproteins of endothelial origin, or derived from pericytes, intravascular leukocytes, and plasma, are other important components of the glycoca

Research shows that pornography holds great influential power in relation to the sexual desires and preferences of its consumers, and that it greatly affects how people view sex and intimacy. When pornography displays acts of sexual violence, acts of aggressions, this influential power constitutes a cause for concern. It has been shown that consumption of pornography featuring aggression contribut

AIMS: Heart failure (HF) is a frequent condition in the elderly, further complicated by associated pulmonary hypertension (PH), with impact on morbidity and mortality. Plasma proteins associated with cardiovascular disease, related to inflammation, neurohormonal changes, and myocyte stress, pathways recognized in the pathophysiology of HF, may provide information on disease severity and prognosis.

Bacterial proteases are important enzymes used in several technical applications where controlled cleavage of proteins is needed. They are challenging enzymes to express recombinantly as parts of the proteome can be hydrolyzed by their activity. The eukaryotic model organism Saccharomyces cerevisiae is potentially a good expression host as it tolerates several stress conditions and is known to bet

Från IgG till IgA: En omvandling som hämmade fagocytos av SARS-CoV-2 spike-kulor Sedan slutet av 2019 har COVID-19 pandemin orskat förödande konskekvenser för både människa och hälsa, med miljontals döda och en djup socioekonimsk inverkan. Boven bakom denna pandemi är viruset Severe Acute Respiratory Syndrome Corona Virus 2, eller SARS-CoV-2. Ett av våra viktigaste skydd mot SARS-CoV-2 är antikro

The purpose of this thesis is to investigate the techniques that scammers and scambaiters use in phone conversations to deceive each other and accomplish their respective goals. Seeing how the number of people losing money to scams continues to rise every year, there is an urgent need for more research to raise awareness of common scam tactics. It is also highly sociologically relevant to gain an

Cycling has been increasing in popularity in many countries, including the Republic of Ireland. Concurrently, the modal share of cyclist casualties has been increasing. However, there has been limited analysis of the pre-crash manoeuvres and impact configurations of cyclist collisions in Ireland, which inhibits the prioritization of engineering solutions. Accordingly, in this study, police investi

Computer vision/deep learning-based 3D human pose estimation methods aim to localize human joints from images and videos. Pose representation is normally limited to 3D joint positional/translational degrees of freedom (3DOFs), however, a further three rotational DOFs (6DOFs) are required for many potential biomechanical applications. Positional DOFs are insufficient to analytically solve for joint

Estimating crop evapotranspiration (ETa) is an important requirement for a rational assessment and management of water resources. The various remote sensing products allow the determination of crops’ biophysical variables integrated in the evaluation of ETa by using surface energy balance (SEB) models. This study compares ETa estimated by the simplified surface energy balance index (S-SEBI) using