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Ionic Liquid Ordering at an Oxide Surface
The interaction of the ionic liquid [C4C1Im][BF4] with anatase TiO2, a model photoanode material, has been studied using a combination of synchrotron radiation photoelectron spectroscopy and near-edge X-ray absorption fine structure spectroscopy. The system is of interest as a model for fundamental electrolyte–electrode and dye-sensitized solar cells. The initial interaction involves degradation o
Experiences of attitudes in Sierra Leone from the perspective of people with poliomyelitis and amputations using orthotics and prosthetics
Purpose: The aim of this study was to describe experiences of attitudes in the society of Sierra Leone from the perspective of individuals with poliomyelitis and people with amputations using orthotic or prosthetic devices. Methods: Individual interviews were conducted using open-ended questions. Twelve participants with amputations or polio were included. Content analysis was applied to the data.
A typology of political participation online : How citizens used Twitter to mobilize during the 2015 British general elections
This study investigates how, and to what extent, citizens use Twitter as a platform for political mobilization in an electoral context. Conceptualizing political participation as a process, we develop a typology of political participation designed to isolate mobilizing calls for action from the rest of the political discussion online. Based on Twitter data collected one week prior to the 2015 Brit
A novel enzyme with antioxidant capacity produced by the ubiquitous skin colonizer Propionibacterium acnes
The role of the skin microbiota in human health is poorly understood. Here, we identified and characterized a novel antioxidant enzyme produced by the skin microbiota, designated RoxP for radical oxygenase of Propionibacterium acnes. RoxP is uniquely produced by the predominant skin bacterium P. acnes, with no homologs in other bacteria; it is highly expressed and strongly secreted into culture su
ESS target helium experiments at Lund University
In ESS, a 5 MW proton beam will hit a helium cooled tungsten target to generate neutrons by spallation. For the purpose of investigating various aspects of cooling with helium, an experimental system has been constructed at Lund University, Department of Energy Sciences. A helium flow of 3 g/s is circulated in a closed loop with pre-heater, cooler, filters and a test vessel. The vessel has windows
Student explanations of their science teachers’ assessments, grading practices and how they learn science
The current paper draws on data generated through group interviews with students who were involved in a larger ethnographic research project performed in three science classrooms. The purpose of the study from which this data was generated, was to understand science teachers’ assessment practices in an upper-secondary school in Sweden. During group interviews students were asked about their concep
From Old Country to New Haven and Back Again in Times of Boom and Bust
Reporting of complex interventions in clinical trials : Development of a taxonomy to classify and describe fall-prevention interventions
Interventions for preventing falls in older people often involve several components, multidisciplinary teams, and implementation in a variety of settings. We have developed a classification system (taxonomy) to describe interventions used to prevent falls in older people, with the aim of improving the design and reporting of clinical trials of fall-prevention interventions, and synthesis of eviden
Land-atmosphere feedbacks amplify aridity increase over land under global warming
The response of the terrestrial water cycle to global warming is central to issues including water resources, agriculture and ecosystem health. Recent studies indicate that aridity, defined in terms of atmospheric supply (precipitation, P) and demand (potential evapotranspiration, E p) of water at the land surface, will increase globally in a warmer world. Recently proposed mechanisms for this res
Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release
UNLABELLED: Persistent CB1 cannabinoid receptor activity limits neurotransmitter release at various synapses throughout the brain. However, it is not fully understood how constitutively active CB1 receptors, tonic endocannabinoid signaling, and its regulation by multiple serine hydrolases contribute to the synapse-specific calibration of neurotransmitter release probability. To address this questi
Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe
Purpose: In Gaucher disease, diminished activity of the lysosomal enzyme, acid β-glucosidase, leads to accumulation of glucosylceramides and related substrates, primarily in the spleen, liver, and bone marrow. Eliglustat is an oral substrate reduction therapy approved in the European Union and the United States as a first-line treatment for adults with type 1 Gaucher disease who have compatible CY
To distribute or not to distribute? Impact of latency on Virtual Network Function distribution at the edge of FMC networks
The Network Function Virtualization paradigm enables the possibility to dynamically instantiate Virtual Network Functions (VNFs) in Commercial-Off-The-Shelf (COTS) hardware. Such VNFs are then concatenated together in Service Chains (SCs) to provide specific Internet services to the users. Depending on latency requirements for such services and considering the aim of maximally consolidating the VN
Do the energy fluxes and surface conductance of boreal coniferous forests in Europe scale with leaf area?
Earth observing systems are now routinely used to infer leaf area index (LAI) given its significance in spatial aggregation of land surface fluxes. Whether LAI is an appropriate scaling parameter for daytime growing season energy budget, surface conductance (Gs), water- and light-use efficiency and surface–atmosphere coupling of European boreal coniferous forests was explored using eddy-covariance
Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis
Cancer-associated fibroblasts (CAFs) interact with tumour cells and promote growth and metastasis. Here, we show that CAF activation is reversible: chronic hypoxia deactivates CAFs, resulting in the loss of contractile force, reduced remodelling of the surrounding extracellular matrix and, ultimately, impaired CAF-mediated cancer cell invasion. Hypoxia inhibits prolyl hydroxylase domain protein 2
STRIPAK components determine mode of cancer cell migration and metastasis
The contractile actomyosin cytoskeleton and its connection to the plasma membrane are critical for control of cell shape and migration. We identify three STRIPAK complex components, FAM40A, FAM40B and STRN3, as regulators of the actomyosin cortex. We show that FAM40A negatively regulates the MST3 and MST4 kinases, which promote the co-localization of the contractile actomyosin machinery with the E
Tumour hypoxia and the hypoxia inducible transcription factors: Key players in cancer progression and metastasis
Humour and Happiness in an NPM World : Do They Speak in Jest?
This study examines perceptions of humour and happiness in a world where NPM ideas have a profound influence on many aspects of everyday living. The researchers interviewed comedians and their circle of co-workers at comedy festivals. Comedians seek to make us laugh, but this paper examines whether they have a serious message, too. This research reveals comedians as critical thinkers, as edge-workThis study examines perceptions of humour and happiness in a world where NPM ideas have a profound influence on many aspects of everyday living. The researchers interviewed comedians and their circle of co-workers at comedy festivals. Comedians seek to make us laugh, but this paper examines whether they have a serious message, too. This research reveals comedians as critical thinkers, as edge-work
Flame stabilization and emission characteristics of a prototype gas turbine burner at atmospheric conditions
In the present work, a downscaled prototype 4th generation Dry Low Emission gas turbine (SGT-750) burner (designed and manufactured by Siemens Industrial Turbomachinery AB, Sweden) was investigated using an atmospheric experimental facility. The primary purpose of the research is to analyze flame stability and emission capability of the burner. OH Planar Laser-Induced Fluorescence (OH-PLIF), and c
A combination of parabolic and grid slope interpolation for 2D tissue displacement estimations
Parabolic sub-sample interpolation for 2D block-matching motion estimation is computationally efficient. However, it is well known that the parabolic interpolation gives a biased motion estimate for displacements greater than |y.2| samples (y = 0, 1, …). Grid slope sub-sample interpolation is less biased, but it shows large variability for displacements close to y.0. We therefore propose to combin