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Membrane performance during ultrafiltration of a high-viscosity solution containing hemicelluloses from wheat bran

Hemicelluloses isolated from agricultural residues have the potential to replace fossil-based materials in high-value-added applications, provided that cost-efficient isolation processes are developed. In this study, a feed solution containing hemicelluloses extracted from wheat bran with a particular high viscosity was used to study the performance of ultrafiltration for hemicellulose isolation a

Translation and cultural adaptation of research instruments - guidelines and challenges: an example in FAMCARE-2 for use in Sweden

Background: Assessing and evaluating health care is important, and an abundance of instruments are developed in different languages. Translating existing, validated instruments is demanding and calls for adherence to protocol. Purpose: The purpose of this study was to translate and culturally adapt the FAMCARE-2 scale for use in Sweden. Methods: Traditional back-translation and the decentering sta

Search for new phenomena in events with three charged leptons at root s=7 TeV with the ATLAS detector

A generic search for anomalous production of events with at least three charged leptons is presented. The search uses a pp-collision data sample at a center-of-mass energy of root s = 7 TeV corresponding to 4.6 fb(-1) of integrated luminosity collected in 2011 by the ATLAS detector at the CERN Large Hadron Collider. Events are required to contain at least two electrons or muons, while the third le

Urban Transport Transitions: Copenhagen, City of Cyclists.

Mobility growth poses considerable challenges to city planners around the world, as it entails problems of congestion, air pollution, and accidents. Many cities have thus sought to increase the share of sustainable transport, and specifically travel by bicycle. However, it appears that measures to foster cycling are often implemented on an ad hoc basis, lacking strategic focus and a more profound

BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.

Triple negative (TN) breast cancers make up some 15% of all breast cancers. Approximately 10-15% are mutant for the tumor suppressor, BRCA1. BRCA1 is required for homologous recombination-mediated DNA repair and deficiency results in genomic instability. BRCA1-mutated tumors have a specific pattern of genomic copy number aberrations that can be used to classify tumors as BRCA1-like or non-BRCA1-li

Topological performance measures as surrogates for physical flow models for risk and vulnerability analysis for electric power systems.

Critical infrastructure systems must be both robust and resilient in order to ensure the functioning of society. To improve the performance of such systems, we often use risk and vulnerability analysis to find and address system weaknesses. A critical component of such analyses is the ability to accurately determine the negative consequences of various types of failures in the system. Numerous mat

Quantifying the constraint of biospheric process parameters by CO2 concentration and flux measurement networks through a carbon cycle data assimilation system

The sensitivity of the process parameters of the Biosphere Energy Transfer HYdrology (BETHY) model to choices of atmospheric concentration network, high frequency terrestrial fluxes, and the choice of flux measurement network is investigated by using a carbon cycle data assimilation system. We use BETHY-generated fluxes as a proxy of flux measurements. Results show that monthly mean or low-frequen

Plasmid DNA purification using a multimodal Chromatography resin

Abstract in UndeterminedMultimodal chromatography is widely used for isolation of proteins because it often results in improved selectivity compared to conventional separation resins. The binding potential and chromatographic behavior of plasmid DNA have here been examined on a Capto Adhere resin. Capto Adhere is a recent multimodal chromatography material allowing molecular recognition between th

Intratumoral temozolomide synergizes with immunotherapy in a T cell-dependent fashion.

Despite temozolomide (TMZ) treatment, the prognosis for patients with glioblastoma multiforme is still dismal. As dose escalation of TMZ is limited by systemic toxicity, intratumoral delivery emerges as an attractive treatment modality, which may sustain cytotoxic drug concentrations intratumorally and induce immunogenic cell death. Both clinical and experimental gliomas have responded to immunoth

Thermal optimality of net ecosystem exchange of carbon dioxide and underlying mechanisms.

• It is well established that individual organisms can acclimate and adapt to temperature to optimize their functioning. However, thermal optimization of ecosystems, as an assemblage of organisms, has not been examined at broad spatial and temporal scales. • Here, we compiled data from 169 globally distributed sites of eddy covariance and quantified the temperature response functions of net ecosys

Marked variability in clinical presentation and outcome of patients with C1q immunodeficiency.

Globally approximately 60 cases of C1q deficiency have been described with a high prevalence of Systemic Lupus Erythematosus (SLE). So far treatment has been guided by the clinical presentation rather than the underlying C1q deficiency. Recently, it was shown that C1q production can be restored by allogeneic hematopoietic stem cell transplantation. Current literature lacks information on disease p

Intra-operative Cone Beam Computed Tomography can Help Avoid Reinterventions and Reduce CT Follow up after Infrarenal EVAR.

Re-interventions after endovascular abdominal aortic aneurysm repair (EVAR) are common and therefore a strict imaging follow up protocol is required. The purpose of this study was to evaluate whether cone beam computed tomography (CBCT) can detect intra-operative complications and to compare this with angiography and the 1 month CT follow up (computed tomography angiography [CTA]).

Prevalence, awareness, treatment, and control of hypertension: Rule of thirds in the Skaraborg project

Objective. To describe the prevalence, awareness, and control of hypertension in a Swedish population during the early 2000s to address implications for care and prevention. Design. A cross-sectional population survey. Setting. Primary health care in Skaraborg, a rural part of western Sweden. Subjects. Participants (n = 2816) in a population survey of a random sample of men and women between 30 an

Pulse Pressure, Arterial Stiffness, and End-Organ Damage

Whereas larger arteries participate in the dampening of blood pressure (BP) oscillations resulting from intermittent ventricular ejection, smaller arteries steadily deliver an adequate supply of blood from the heart to the peripheral organs. Numerous active mechanisms are involved in this process. Cyclic stress acts differently from steady stress, inducing stronger and stiffer material of the vess