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Monitoring of in situ remediation with the direct current time-domain induced polarization method

In Alingsås, a dry-cleaning facility was operated for many years, and huge amounts of the solvent PCE was spilled into the ground. This contributed to an increasing concentration of PCE over the years until the use of PCE was stopped, resulting in the formation of a DNAPL plume beneath the building. Treatment of contaminated soils in Sweden often includes excavation and landfilling, however in Ali

Meaning of home and health dynamics among younger older people in Sweden

Research has shown that positive evaluations of home are important for very old people’s health, well-being and independence in daily life. The rationale for the present study derives from our survey study findings, confirming such associations also in a younger cohort (N = 371). The purpose of this study was to further increase the understanding of the dynamics of meaning of home and health among

Single-shot extreme-ultraviolet wavefront measurements of high-order harmonics

We perform wavefront measurements of high-order harmonics using an extreme-ultraviolet (XUV) Hartmann sensor and study how their spatial properties vary with different generation parameters, such as pressure in the nonlinear medium, fundamental pulse energy and duration as well as beam size. In some conditions, excellent wavefront quality (up to 휆/11) was obtained. The high throughput of the inten

Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin

Plasma-membrane Ca2+-ATPases expel Ca2+ from the cytoplasm and are key regulators of Ca2+ homeostasis in eukaryotes. They are autoinhibited under low Ca2+ concentrations. Calmodulin (CaM)-binding to a unique regulatory domain releases the autoinhibition and activates the pump. However, the structural basis for this activation, including the overall structure of this calcium pump and its complex wi

Regulation of inflammasomes by host- and pathogen-derived factors

The term inflammasome was first coined in 2002 and describes an intracellular multiprotein complex mediating inflammation by inducing the release of pro-inflammatory cytokines (IL-1β and IL-18) and a lytic form of cell death called pyroptosis. Since then, an impressive amount of research has revealed many details about the mechanisms of inflammasome activation as well as the functional relevance o

Which clinical and sociodemographic determinants are associated with self-perceived manual ability at one year after stroke?

Purpose: To evaluate the impact of multiple potential sociodemographic and clinical stroke-related determinants on self-perceived manual ability in an unselected sample of individuals 12 months after first-ever stroke. Methods: A cross-sectional sample of 68 participants (mean age 66) with UE impairments were followed up at 12 months post stroke. Stroke severity at onset was moderate for the major

Risk of imminent fracture following a previous fracture in a Swedish database study

Summary: This study examined the imminent risk of a future fracture within 1 and 2 years following a first fracture in women aged 50 years and older and assessed independent factors associated with risk of subsequent fractures. The study highlights the need to intervene rapidly after a fracture to prevent further fractures. Introduction: This study aims to determine the imminent risk of subsequent

Anti-Fascist Race Biology : Gunnar Dahlberg and the Long Farewell to the Nordic 'Master Race'

On the evening of 6 December 1933, members of the National Socialist Party of Sweden (SNSP, Sveriges Nationalsocialistiska Parti), at this time the most aggressive Nazi organisation in the country, violently attacked a lecture at Stockholm University. This gave rise to an extensive press debate; newspapers from left to right condemned the attack, which ended up being a propaganda fiasco for SNSP.

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

Understanding the driving forces underlying molecular recognition is of fundamental importance in chemistry and biology. The challenge is to unravel the binding thermodynamics into separate contributions and to interpret these in molecular terms. Entropic contributions to the free energy of binding are particularly difficult to assess in this regard. Here we pinpoint the molecular determinants und

Latent Semantic Analysis Discriminates Children with Developmental Language Disorder (DLD) from Children with Typical Language Development

Computer based analyses offer a possibility for objective methods to assess semantic-linguistic quality of narratives at the text level. The aim of the present study is to investigate whether a semantic language impairment index (SELIMI) based on latent semantic analysis (LSA) can discriminate between children with developmental language disorder (DLD) and children with typical language developmen

Enantioselective synthesis of : Anti -3-alkenyl-2-amido-3-hydroxy esters: Application to the total synthesis of (+)-alexine

A straightforward synthesis of anti-3-alkenyl-2-amido-3-hydroxy esters from the corresponding racemic α-amino-β-keto esters by using a ATH/DKR protocol has been developed. This method gives moderate to excellent yields with high chemo-, diastereo- and enantioselectivities for a broad range of substrates. In order to highlight the versatility of the methodology it was applied in an efficient asymme

Acute uncomplicated diverticulitis managed without antibiotics–difficult to introduce a new treatment protocol but few complications

Objective: Routine antibiotic treatment of acute uncomplicated diverticulitis (AUD) has been shown ineffective. In this study, the adherence to a new treatment protocol for uncomplicated diverticulitis was evaluated and the incidence of complications in patients treated with and without antibiotics was investigated. Materials and methods: A retrospective study of in-patients diagnosed with AUD at