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Breast cancer is the major cause of deaths related to cancer for women worldwide. Although much is known about this malignancy, extensive research is still needed to gain complete understanding of the complexity of the disease. The inter and intra tumor heterogeneity is an important trait of breast cancer. The intratumor heterogeneity is reflected in sub-populations of cancer cells that appear to Breast cancer is the major cause of deaths related to cancer for women worldwide. Although much is known about this malignancy, extensive research is still needed to gain complete understanding of the complexity of the disease. The inter and intra tumor heterogeneity is an important trait of breast cancer. The intratumor heterogeneity is reflected in sub-populations of cancer cells that appear to

OBJECTIVE: This study examined the prevalence and correlates of physical violence and rape among female sex workers (FSWs) in Ethiopia.DESIGN: A cross-sectional study using respondent-driven sampling technique.SETTING: Eleven major towns in Ethiopia.PARTICIPANTS: 4900 FSWs.MAIN OUTCOME MEASURES: The prevalence of experiences of physical beating and rape.RESULTS: Among FSWs, 17.5% reported physical

In this work, we study the formation and chemical evolution of the Galactic bulge with particular focus on the abundance pattern ([Mg/Fe] versus [Fe/H]), metallicity, and age distribution functions. We consider detailed chemical evolution models for the Galactic bulge and inner disc, with the aim of shedding light on the connection between these components and the origin of bulge stars. In particu

The application of the Chao-Raimondi emittance adapter to the SOLEIL storage ring is studied theoretically in terms of linear and nonlinear beam dynamics. This unique scheme recently proposed elsewhere using a pair of emittance adapters and a solenoid in between them allows a local conversion of an electron beam in a third generation light source to an ultralow emittance beam of the fourth generat

MicroRNAs (miRNA) play an important role in various biological process by regulating gene expression. Their abnormal expression may lead to cancer. Therefore, analysis of such data may discover potential biological insight for cancer diagnosis. In this regard, recently many feature selection methods have been developed to identify such miRNAs. These methods have their own merits and demerits as th

The grand challenges of contemporary fundamental physics-dark matter, dark energy, vacuum energy, inflation and early universe cosmology, singularities and the hierarchy problem-all involve gravity as a key component. And of all gravitational phenomena, black holes stand out in their elegant simplicity, while harbouring some of the most remarkable predictions of General Relativity: event horizons,

Nanoparticle generation by aerosol methods, particularly spark ablation, has high potential for creating new material combinations with tailored magnetic properties. By combining elements into complex alloyed nanoparticles and controlling their size and structure, different magnetic properties can be obtained. In combination with controlled deposition, to ensure nanoparticle separation, it is poss

Silicon pixel detectors are at the core of the current and planned upgrade of the ATLAS experiment at the LHC. Given their close proximity to the interaction point, these detectors will be exposed to an unprecedented amount of radiation over their lifetime. The current pixel detector will receive damage from non-ionizing radiation in excess of 1015 1 MeV neq/cm2, while the pixel detector designed

This study discusses economic crises and crisis preparedness in Sweden. The message may be summarized in four points: (i) economic crises are a recurrent element in Swedish economic history, (ii) economic crises have far-reaching political effects, (iii) economic crises change the design of economic policies and institutions, and (iv) new crises will occur in the future. A major method to prepare

Through an analysis of documentary audiences for The Act of Killing (2012) and The Look of Silence (2014), this article explores the idea of provocative engagement as a way of extending our understanding of the affective dimensions of documentary and its role in civic engagement. The study draws on qualitative empirical research, based on interviews with the filmmaker, and interviews with fifty-tw

Background: Mechanisms related to the influence of diet on the development of cardiovascular disease are not entirely understood, and protein biomarkers may help to understand these pathways. Studies of biomarkers identified with multiplex proteomic methods and dietary patterns are largely lacking. Methods and Results: Dietary patterns were generated through principal component analysis in 2 popul

Objectives Global incidence and attention to childhood cancer is increasing and treatment abandonment is a major cause of treatment failure in low-and middle-income countries. The purpose of this study was to gain an understanding of factors contributing to non-adherence to treatment. Design A prospective cohort study with 2 year follow-up of incidence, family-reported motives and risk factors. Se

Background: Roux-en-Y gastric bypass (RYGB) is an effective obesity treatment in adults and has become established in adolescents. Lower adherence to supplementation in adolescents confers a risk for long-term nutritional deficiencies. Objectives: To assess adherence to supplementation, micronutrient intake, and biochemistry in adolescents through 5 years after RYGB. Setting: University hospitals,

Modern age is the age of integration, where millions of electronic components are integrated and installed on a single chip, to minimize the size of device and automatically increases the speed. But, as a greater number of components are placed on a single device, reliability becomes a concern issue, as failure of one component can degrade the complete device. From dimmer to high voltage power tra