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3,4-Dideoxyglucosone-3-ene (3,4-DGE): A cytotoxic glucose degradation product in fluids for peritoneal dialysis

Background. Bioincompatible glucose degradation products (GDPs) in fluids for peritoneal dialysis (PD) develop during sterilization and storage. Their biological activity has successfully been monitored through the use of various in vitro methods but their molecular and chemical nature is less well understood. Many GDPs are highly reactive carbonyl compounds. Although some of the identified GDPs a

The Rest on the Flight into Egypt: A motif in Scandanavian folk art

Although there is no biblical account of the 'Rest on the Flight into Egypt', the story is well known in the Christian world. In pseudo-Matthew the story has developed into legend form. He tells about the Christ-Child commanding the date palm Mary is resting beneath to bend down so that she can eat the fruit. It is found in literary sources from the twelfth century onwards. 'The Rest on the Flight

Surface chemistry of TiCl4 on clean and hydrogen modified W(110): identification of surface intermediates

The adsorption and decomposition of titanium tetrachloride (TiCl4) on W(110) were studied with high-resolution core level photoelectron spectroscopy. At least two stable intermediates are formed along the pathway to TiCl4 decomposition: TiCl4(a), which is stable up to 300 K, and TiCl3(a), which is stable up to 500 K. Successive adsorption at 80 K shows that the TiCl4() species forms in the presenc

Quantitative bone scintigraphy in patients with prostatic carcinoma treated with LH-RH analogues

In 14 men with prostatic carcinoma, quantitative scintigraphy of the vertebrae from Th10 to L5 was performed before and 2 weeks and 2 and 6 months after start of treatment with luteinizing hormone-releasing hormone (LH-RH) analogues. Serum prostate-specific antigen (PSA) was also determined. The patients with normal bone scintigram showed no change in gamma camera count rate during the study, but

Lack of interference between IgA-binding proteins and IgA proteases of human pathogenic bacteria

Some human bacterial pathogens produce specific immunoglobulin A1 (IgA1) proteases that cleave the heavy chain of human IgA1, generating intact Fab and Fc fragments. Other pathogenic bacterial species express surface proteins which bind to the Fc part of human IgA in a non-immune manner. To analyse whether IgA-binding proteins affect the activity of IgA1 proteases, the ability of seven different I

The role of uncoupling proteins in the regulation of metabolism.

Investigations of variations in metabolic efficiency and thermogenesis have a short and turbulent history. In small animals, non-shivering thermogenesis and diet-induced thermogenesis have a great impact on overall body weight, and the question is whether mechanisms to waste energy have evolved also in human energy metabolism. The candidate molecules for this adaptive thermogenesis are the uncoupl

Supercharged Homogeneous Charge Compression Ignition

The Homogeneous Charge Compression Ignition (HCCI) is the third alternative for combustion in the reciprocating engine. Here a homogeneous charge is used as in a spark-ignited engine, but the charge is compressed to autoignition as in a diesel. The main difference compared with the Spark Ignition (SI) engine is the lack of flame propagation and hence the independence from turbulence. Compared with

The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases

A breast cancer-associated mRNA originally cloned as a 475-bp partial cDNA from a library enriched for tumour cDNAs [Oncogene 16 (1998) 327] is expressed at high levels in breast and prostate cancer cells. Immunohistochemical analysis indicates that the protein is expressed in primary breast tumours. We used RT-PCR to generate a full-length 2852 nt mRNA sequence that includes the hypothetical open

Triphenylphosphine-substituted selenido and sulfido clusters of osmium derived from Ph3P=Se or Ph3P=S

Cleavage of P=Se bonds occurs readily in the room-temperature treatment of [Os-3(CO) (10)(MeCN)(2)] with Ph3P=Se to give three new compounds, [Os-3(mu(3)-Se)(2)(CO)(8)(PPh3)] (2), [Os-3(mu(3)-Se)( mu(3)-CO)(CO)(7)(PPh3)(2)] (5) and [Os3(mu-OH)(2)(CO)(8)(PPh3)(2)] (6), respectively, and three known compounds, [Os-3(mu(3)-Se)(2)(CO)(9)] (1), [Os-3(mu(3)-Se)(mu-CO)(2)(CO)(7)(PPh3)] (3), and 1,2-[Os-3

Essays on Empirical Macroeconomics

Popular Abstract in Swedish Denna avhandling består av 5 fristående uppsatser i makroekonomi. Den första uppsatsen behandlar agregerad privat konsumtion. Det har nyligen föreslagits att hushållens konsumtion av icke-varaktiga varor reagerar asymmetriskt på positiva och negativa inkomstförväntningar. I denna uppsats undersöker vi huruvida detta är beroende på hur hushållens förväntningar modelleraThe first essay reexamines the proposed presence of so-called loss aversion in aggregate consumption. Recent empirical and theoretical studies have suggested, that consumption growth reacts asymmetrically to positive and negative expected income growth. After investigating the case for Swedish consumption using survey data, and a panel of annual observations on 15 OECD countries, we conclude that

Topics in Complex Analysis and Operator Theory I. The shift operator on spaces of vector-valued analytic functions II. Fatou-type theorems for general approximate identities III. Preduals of Q_p-spaces

Popular Abstract in Swedish Del I - "The Shift Operator on Spaces of Vector-valued Analytic Functions" består av tre artiklar som alla handlar om en viss sorts operatorer i Cowen-Douglas klassen med spektrum på enhetsskivan D, eller om man så vill, om operatorn Mz (multiplikation med z) på Hilbert rum H av vektorvärda analytiska funktioner på D. Den första artikeln, "On the Cowen-Douglas class forThis thesis consists of six articles on three different subjects in the area of complex analysis, operator theory and harmonic analysis. Part I - "The Shift Operator on Spaces of Vector-valued Analytic Functions" consists of three closely connected articles that investigate certain operators in the Cowen-Douglas class with spectrum D - the unit disc, or equivalently, the shift operator M_z

Leaving Home in a Peasant Society. Economic Fluctuations, Household Dynamics and Youth Migration in Southern Sweden, 1829-1866.

Popular Abstract in Swedish Avhandlingen behandlar barns flyttningar hemifrån i det förindustriella bondesamhället. Utöver att studera när barn lämnade hemmet kopplas också flyttningsprocessen till den förindustriella hushållsekonomins funktionssätt. Analysen görs på ett longitudinellt material för ett område i västra Skåne under perioden 1829-1866. Individerna följs från födseln, eller från det aThis study deals with the process of children leaving home and its interactions with the household economy in preindustrial society. A theoretical model of leaving home is outlined and then analyzed multivariately, using a longitudinal micro-level dataset for a sample of parishes in western Scania, Sweden, for the period 1829-1866. In a first introductory part the social and economic background as

Mechanistic information on the reaction of cis- and trans-[RuCl2(DMSO)(4)] with d(T(2)GGT(2)) derived from MALDI-TOF and HPLC studies

Reactions of trans and cis isomers of the Ru-II complex [RuCl2(DMSO)(4)] with single-stranded hexanucleotide d(T(2)GGT(2)) were studied in aqueous solutions in the absence and presence of excess chloride by high performance liquid chromatography (HPLC) and matrix-assisted laser desorption/ionisation time of flight mass spectrometry (MALDI-TOF MS). Despite the different reactive species formed from

General practitioners' conceptions about treatment of depression and factors that may influence their practice in this area. A postal survey

BACKGROUND: The way GPs work does not appear to be adapted to the needs of depressive patients. Therefore we wanted to examine Swedish GPs' conceptions of depressive disorders and their treatment and GPs' ideas of factors that may influence their manner of work with depressive patients. METHODS: A postal questionnaire to a stratified sample of 617 Swedish GPs. RESULTS: Most respondents assumed ant

Apolipoprotein M: Progress in understanding its regulation and metabolic functions

ApoM is a novel apolipoprotein mainly present in high-density lipoprotein (HDL). It belongs to the lipocalin protein superfamily and may bind a small but so far unknown lipophilic ligand. It is secreted without cleavage of its hydrophobic signal peptide, which probably anchors apoM in the phospholipid moiety of plasma lipoproteins. Recent studies suggest that apoM may affect HDL metabolism and hav

Greater reduction of knee than hip pain in osteoarthritis treated with naproxen, as evaluated by WOMAC and SF-36

Objectives: To compare the improvement of hip and knee osteoarthritis during treatment with naproxen. Methods: Men and women aged 40 to 75 years with symptomatic osteoarthritis of the knee or hip of at least three months' duration participated in a six week placebo controlled, double blind study with naproxen 500 mg twice daily as one treatment arm. Naproxen was given to 403 patients (280 knee, 12

The Euro cash changeover process

This article describes and analyzes the Euro cash changeover process. The European Monetary Union, EMU, is a unique event in history, although other monetary unions were formed and existed long before. Still, this giant experiment makes it possible to study changes in the monetary environment from a unique and new position. The article tries to find factors that can help to explain the different p