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The use and characterization of a backilluminated charge-coupled device in investigations of pulsed x-ray and radiation sources.

Examinations of bremsstrahlung and energetic electron beams from a novel laser plasma source motivate and assist characterization of a backthinned, backilluminated direct detection x-ray charge-coupled device (CCD), a topology that is uncommon in hard x-ray work. Behavior toward pseudomonochromatic ((55)Fe) and multichromatic ((241)Am) sources is briefly reviewed under optimized noise conditions.

Globalisation of Knowledge Production and Regional Innovation Policy: Supporting Specialized Hubs in Developing Countries

This paper is concerned with the changing role of regional innovation systems and regional policies in supporting the transition of indigenous firms in developing countries from competing on low costs towards becoming knowledge providers in global value chains. Special attention is paid to policies supporting the emergence and development of the regional innovation system in this transition proces

Two icodextrin exchanges per day in peritoneal dialysis patients with ultrafiltration failure: one center's experience and review of the literature

At present, only one exchange of an icodextrin-based solution is recommended to increase peritoneal ultrafiltration (UF) during long-dwell exchanges in peritoneal dialysis (PD) patients with impaired UF. To review our experience with two icodextrin exchanges per day on net UF and body weight in PD patients with poor UF. Data were analyzed on nine patients with poor UF on chronic PD who were given

Reliability study of friction stir welded copper canisters containing Sweden's nuclear waste

The plan for the final disposal of spent fuel front Swedish nuclear power plants is to place it in copper canisters that are sealed and stored in a deep repository. The canisters will be sealed by friction stir welding (FSW) and the reliability of this process has now been evaluated. The reliability study was performed in three steps: first an optimization experiment to identify optimal process se

Battling Bacterial Biofilm - antibiotic regimens targeting Grampositive pathogens in biofilm

Popular Abstract in Swedish Vår hud och våra slemhinnor är ständigt koloniserade med bakterier som lever i fredligt samspel med vår organism. Dessa bakterier tillhör vår normalflora och kan indelas i kommensaler respektive opportunistiska bakterier. Kommensalerna gagnar värden på olika sätt och orsakar inte sjukdom, till skillnad från opportunisterna som under vissa betingelser kan orsaka infektioAbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and protein, forming organized communities called biofilms. In the biofilm bacteria are protected against hostile environments. Biofilms are important clinically because of their persistence despite host defence and their recalcitrance to antimicrobials. This thesis presents three main findings: (i) biof

Compton scattering from deuterium and the polarizabilities of the neutron

A new program of Compton scattering on deuterium is under way at the tagged-photon facility at MAX-Lab in Lund, Sweden. We will measure differential cross sections between 60A degrees and 150A degrees over the photon energy range 60-115 MeV in 5 MeV steps, with the ultimate goal of obtaining new precision information on the electric and magnetic polarizabilities of the neutron.

Campylobacter jejuni Colonization in Wild Birds: Results from an Infection Experiment

Campylobacter jejuni is a common cause of bacterial gastroenteritis in most parts of the world. The bacterium has a broad host range and has been isolated from many animals and environments. To investigate shedding patterns and putative effects on an avian host, we developed a colonization model in which a wild bird species, the European Robin Erithacus rubecula, was inoculated orally with C. jeju

Interpretation of response categories in patient-reported rating scales: a controlled study among people with Parkinson's disease

Background: Unambiguous interpretation of ordered rating scale response categories requires distinct meanings of category labels. Also, summation of item responses into total scores assumes equal intervals between categories. While studies have identified problems with rating scale response category functioning there is a paucity of empirical studies regarding how respondents interpret response ca

Adaptation and learning in postural control

The importance of the ability to use bipedal stance and gait in everyday life cannot be underestimated. Bipedal stance is learned during childhood and constantly adapted to changing circumstances throughout life. Failure to attain and maintain the control of upright posture can have catastrophic consequences. Postural competence needs to be recovered in a multitude of illness, in developmental dis

Haptoglobin Binding Stabilizes Hemoglobin Ferryl Iron and the Globin Radical on Tyrosine beta 145

Aim: Hemoglobin (Hb) becomes toxic when released from the erythrocyte. The acute phase protein haptoglobin (Hp) binds avidly to Hb and decreases oxidative damage to Hb itself and to the surrounding proteins and lipids. However, the molecular mechanism underpinning Hp protection is to date unclear. The aim of this study was to use electron paramagnetic resonance (EPR) spectroscopy, stopped flow opt

The cerebellar microcircuit as an adaptive filter: experimental and computational evidence

Initial investigations of the cerebellar microcircuit inspired the Marr-Albus theoretical framework of cerebellar function. We review recent developments in the experimental understanding of cerebellar microcircuit characteristics and in the computational analysis of Marr-Albus models. We conclude that many Marr-Albus models are in effect adaptive filters, and that evidence for symmetrical long-te

Breast tomosynthesis – new perspectives on breast cancer screening

Popular Abstract in Swedish Bröstcancer är kvinnans vanligaste cancerform och globalt sett den cancer som leder till flest dödsfall. Bröstcancerscreening med mammografi används därför i syfte att hitta cancern tidigt. En tidigt upptäckt cancer har oftast en bättre prognos med möjlighet att minska dödligheten i bröstcancer. Mammografitekniken är dock behäftad med vissa begränsningar vad gäller känsAbstract: Mammography is currently the established method in breast cancer screening, although the sensitivity is known be affected by overlapping tissue concealing tumours. Breast tomosynthesis takes advantage of multiple exposures at different angles reducing the negative effect of obscuring tissue. The aim of this thesis was to investigate the use of tomosynthesis in breast imaging with a spec

The final moments of landing in bumblebees, Bombus terrestris.

In comparison to other insects, like honeybees, bumblebees are very effective pollinators. Even though landing is a crucial part of pollination, little is known about how bumblebees orchestrate the final, critical moments of landing. Here, we use high-speed recordings to capture the fine details of the landing behaviour of free-flying bumblebees (Bombus terrestris), while landing on a flat platfor

Proximates - A Social Context Engine

Several studies have shown the value of using proximity data to understand the social context of users. To simplify the use of social context in application development we have developed Proximates, a social context engine for mobile phones. It scans nearby Bluetooth peers to determine what devices are in proximity. We map Bluetooth MAC ids to user identities on existing social networks which then