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Background Peroxisome proliferator-activated receptor-gamma (PPAR 3) exerts anti-inflammatory effects and is therefore a potential target in ulcerative colitis (UC). A novel PPAR 3 agonist (AS002) developed for local action was evaluated ex vivo in biopsies from UC patients and in vivo in mice with low-grade dextran sodium sulfate (DSS)- and trinitrobenzene sulfonic acid (TNBS)-induced colitis. Me

Background: Optimal adjunctive therapy in ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI (PPCI) remains a matter of debate. Our aim was to compare the efficacy and safety of bivalirudin to unfractionated heparin (UFH), with or without glycoprotein IIb/IIIa inhibitors (GPI) in a large real-world population, using data from the Swedish national registry, SWEDEHE

National and foreign political identities are discursively constructed, not least through the media. Starting from the contention that Europe serves as the main Other used to define the idea of Russia, this article uses media texts (online and press) to analyse how Russia is constructed as a foreign policy actor in relation to Europe and the ‘West’ more generally. In so doing, the article draws on

Despite the total evacuation time of occupants in a multi-storey building not being affected by pedestrian merging on stairs, the calculation of evacuation times in each individual floor depends on the pedestrian merging ratio. In fact, different merging ratios may cause an evacuation to take place from the top to the bottom or vice versa. A simplified simulation model for the calculation of evacu

Objective: Previous studies have shown that both sleep duration and insomnia have an impact on obesity and central obesity. However, studies of the joint effects of these sleep disorders are still sparse. Methods: The present study utilized data from the Swedish EpiHealth cohort study. Participants (45–78 y) were asked to fill out an internet-based questionnaire. Body mass index (BMI) and central

A scheme has been developed permitting the spatial and temporal characterisation of ultrafast dynamics induced by laser driven proton bursts in transparent dielectrics. Advantage is taken of the high degree of synchronicity between the proton bursts generated during laser-foil target interactions and the probing laser to provide the basis for streaking of the dynamics. Relaxation times of electron

Prompt photon production in sNN=2.76-TeV Pb+Pb collisions has been measured by the ATLAS experiment at the Large Hadron Collider using data collected in 2011 with an integrated luminosity of 0.14 nb-1. Inclusive photon yields, scaled by the mean nuclear thickness function, are presented as a function of collision centrality and transverse momentum in two pseudorapidity intervals, |η|

Like many seabirds, auks spend most of the year in offshore areas. Information on which oceanic areas they rely on throughout the winter is therefore important in understanding their population dynamics and establishing appropriate conservation measures. The breeding populations of Thick-billed Murres (Uria lomvia), Common Murres (Uria aalge) and Razorbills (Alca torda) in Iceland have been report

III-V solar cells in the nanowire geometry might hold significant synthesis-cost and device-design advantages as compared to thin films and have shown impressive performance improvements in recent years. To continue this development there is a need for characterization techniques giving quick and reliable feedback for growth development. Further, characterization techniques which can improve under

This book is concerned with how search, searching and with them search engines have become so widely used that we have stopped noticing them. One of society’s key infrastructure for knowing and getting informed are computerised systems supporting the search for and locating of documents and information. The use of these systems, search engines, is curiously dispersed and centralised at the same ti

This work presents a new polyester binder based on 2,5-furandicarboxylic acid (FDCA) as precursors of polyurethane (PU) coatings. The new 100% bio-based structure is composed of four different monomers such as glycerine (Gly), 1,3-propanediol (1,3-PD), 2,5-furandicarboxylic acid (FDCA) and succinic acid (SA). The corresponding PU coating was obtained by crosslinking with a conventional polyisocyan

A search for highly ionizing particles produced in proton-proton collisions at 8 TeV center-of-mass energy is performed by the ATLAS Collaboration at the CERN Large Hadron Collider. The data set used corresponds to an integrated luminosity of 7.0 fb-1. A customized trigger significantly increases the sensitivity, permitting a search for such particles with charges and energies beyond what was prev

This Letter describes a model-agnostic search for pairs of jets (dijets) produced by resonant and non-resonant phenomena beyond the Standard Model in 3.6 fb−1 of proton–proton collisions with a centre-of-mass energy of s=13 TeV recorded by the ATLAS detector at the Large Hadron Collider. The distribution of the invariant mass of the two leading jets is examined for local excesses above a data-deri

Human cystatin C (HCC) is a cysteine protease inhibitor that takes a series of oligomeric forms in solution (e.g., dimers, trimers, tetramers, decamers, dodecamers, and other higher oligomers). The best-known form of cystatin C is the dimer, which arises as a result of a domain swapping mechanism. The formation of the HCC oligomeric forms, which is most likely due to this domain swapping mechanism

För korrekt beskattning i komplicerade mål är det viktigt att Skatteverket kan utvärdera och presentera sakomständigheter på ett kvalificerat sätt. Skattebetalare med hög kompetens har annars större möjligheter att hävda sin rätt jämfört med skattebetalare som saknar sådan kompetens, vilket står i konflikt med likabehandlingsprincipen. I artikeln illustreras vikten av en kvalificerad förvaltningsm

The ZZ production cross section in proton-proton collisions at 13 TeV center-of-mass energy is measured using 3.2 fb-1 of data recorded with the ATLAS detector at the Large Hadron Collider. The considered Z boson candidates decay to an electron or muon pair of mass 66-116 GeV. The cross section is measured in a fiducial phase space reflecting the detector acceptance. It is also extrapolated to a t

The ATLAS experiment has performed extensive searches for the electroweak production of charginos, neutralinos, and staus. This article summarizes and extends the search for electroweak supersymmetry with new analyses targeting scenarios not covered by previously published searches. New searches use vector-boson fusion production, initial-state radiation jets, and low-momentum lepton final states,

The differential cross-section for pair production of top quarks with high transverse momentum is measured in 20.3 fb-1 of proton-proton collisions at a center-of-mass energy of 8 TeV. The measurement is performed for tt¯ events in the lepton+jets channel. The cross-section is reported as a function of the hadronically decaying top quark transverse momentum for values above 300 GeV. The hadronical

The four-lepton (4ℓ, ℓ=e,μ) production cross section is measured in the mass range from 80 to 1000 GeV using 20.3 fb−1 of data in pp collisions at s=8 TeV collected with the ATLAS detector at the LHC. The 4ℓ events are produced in the decays of resonant Z and Higgs bosons and the non-resonant ZZ continuum originating from qq¯, gg, and qg initial states. A total of 476 signal candidate events are o

A search for direct pair production of the supersymmetric partner of the top quark, decaying via a scalar tau to a nearly massless gravitino, has been performed using 20 fb (Formula presented.) of proton–proton collision data at (Formula presented.). The data were collected by the ATLAS experiment at the LHC in 2012. Top squark candidates are searched for in events with either two hadronically dec