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A core outcome set for cranioplasty following stroke or traumatic brain injury - The COAST study

INTRODUCTION: There is substantial heterogeneity in the reporting of outcomes in the global cranioplasty literature. This study aimed to establish a core outcome set (COS) for cranioplasty after decompressive craniectomy for stroke or traumatic brain injury.METHODOLOGY: The scope was defined according to the criteria recommended by the Core Outcome Measures in Effectiveness Trials (COMET) Initiati

A Comparison of Language Processing Models in Political Analysis : Evidence from Sweden

This study evaluates two different natural language processing tech-niques: the normalised co-occurrence (PMI) versus neural networks. Incontrast to most previous studies, the focus is on the context of a propor-tional representation system – Sweden –, where the parties in parliamenttend to form coalitions. We test the models by collecting data from thenational parliament (Swedish Riksdag) and usi

Enhancing healthcare solutions with machine learning-driven adaptive haptic systems

Adaptive haptics, an amalgamation of different haptic systems and machine learning algorithms, has the potential for intelligent feedback in healthcare. Such systems are capable of learning to suit individual user needs in real-time, thereby improving patient care, medical education, and treatment. Targeted techniques of machine learning approaches are reinforcement learning, neural networks, supp

Probabilistic parameter estimation and uncertainty quantification of mode I fracture in wood

The characterisation of wood’s fracture behaviour is a challenging task due to its inherently complex microstructure and natural variability. Consequently, to accurately model wood for engineering applications, deterministic input parameters are rarely sufficient in, for example, finite element models; the stochastic nature of the material must be considered. In the present work, we aim to quantif

Performance of a Zeolite-Filled Slow Filter for Dye Removal and Turbidity Reduction

Ever-increasing global water shortages necessitate more advanced and cost-effective water purification methods. Herein, a novel slow filtration system using natural raw zeolite is proposed as an alternative to traditional quartz sand as a filter medium. The system demonstrates excellent performance in reducing turbidity and removing methylene blue (MB). The natural zeolite-based filtration system

Consensus on the management of traumatic brain injury in older adults : Results from a Delphi study

INTRODUCTION: As the world population is rapidly becoming older, the incidence of traumatic brain injury (TBI) is increasing among older adults with vast implications for brain health of older adults in Europe. Due to differences from younger patients, there are areas of uncertainty in the assessment, diagnosis and management of TBI in older adults.RESEARCH QUESTION: To reach a consensus among exp

No evidence for a link between mental health symptoms and pain thresholds

Background and Objectives: Previous studies have suggested associations between pain perception and psychological factors such as mood, distress, fatigue, and quality of life. However, these factors and their relationship to pain sensitivity have typically been investigated in isolation and with insufficient sample sizes. To address these limitations, we examine the interplay between distinct psyc

Modern handläggning minimerar följder av traumatisk hjärnskada

Traumatic brain injury (TBI) is the leading cause of death among the young, and has an increasing incidence among the elderly. In Sweden there are 20 000 new TBI cases each year, of which most are mild. The primary impact can lead to different types of brain hemorrhages, fractures and diffuse axonal injuries. The level of consciousness is used to define injury severity. Of all TBIs, 4-5 percent re

Kraftig ökning av sjukskrivningar på grund av hjärnskakning

Statistics from the Swedish Social Insurance Agency show a sharp increase in the number of sick leave cases with the diagnoses Concussion, S06.0, and Postconcussional syndrome, F07.2, between the years 2010 and 2022. The reason for the increase has not been established and needs further investigation. One possible reason is that the acute phase treatment recommendations of individuals with mild tr

Mapping bathymetry on Tibetan Plateau lakes using ICESat-2 laser altimetry

Lake water storage variations on the Tibetan Plateau (TP) serve as crucial indicators of regional hydrological dynamics and climate changes, providing more comprehensive insights than discrete measurements of lake area or water level alone. While accurate bathymetric data is fundamental for quantifying lake water storage, conventional bathymetric surveys are often constrained by logistical challen

Replik: Historien ger liberalismen rätt

Daniel Suhonen och Tony Johansson från den fackliga tankesmedjan Katalys vill i Di Debatt 8 december dölja det uppenbara: efterkrigstidens socialdemokratiska regleringar av den svenska kapitalmarknaden höll tillbaka svensk tillväxt i ett halvt sekel, skriver Lars Jonung. professor emeritus, Lunds universitet.

Conclusion

This book comprehensively explores various methodologies and sources used to understand and improve road safety. It delves into the advantages and disadvantages of primary data sources such as police accident records, statistical methods for data analysis, in-depth investigations, healthcare data, self-reporting of behavior, data from automated vehicles, naturalistic driving/cycling/walking studie

The Organisation and Regulation of Door-to-Door Journeys Involving Public Transport : Lessons from Four Countries

Enabling journeys from door-to-door is an essential part of attracting people towards public transport and away from the private car. Facilitating such journeys requires comprehensive and integrated planning across modal and spatial boundaries. Public transport governance, however, is often constrained by fragmented, multi-level structures and regulatory barriers that limit the ability of responsi

Modeling anti-tumor immune responses using patient-derived melanoma organoids

Immune checkpoint blockade (ICB) therapy can restore T cell function in tumors, but not all patients benefit, and the mechanisms behind this remain unclear. In this study, we used patient-derived organotypic (PDO) cultures from metastatic melanoma to examine transcriptomic and cellular changes following ex vivo T cell stimulation. Genomic and transcriptomic features were preserved during PDO forma

Kritisk analys av centrala begrepp i boken städernas stenar

Lars Marcus’s book Städernas stenar (The stones of cities) presentsbasic concepts and the latest directions in the space syntax researcharea. Marcus’s presentation is based on the necessity of understandingthat urban planning as an area of knowledge is comprised of the materialreality of both the city and the “lived city”, human beings, and their useof the city as a tool, of being comprehended as

Mortality After PICU Care: Place Of Death And Impact Of Limitation Of Medical Treatment

AbstractAim: This study sought to investigate the hypothesis that children dying outside a pediatric intensive care unit (PICU) after PICU discharge have a limitation of medical treatment (LOMT) order in place, limiting PICU readmission at the time of death.Methods: A cohort was identified of all children (n=3890; 5019 admissions) treated in a PICU in Sweden over 3 consecutive years between Januar

Effects of Selective Head-and-Neck Cooling on Brain Injury-Related Biomarker Levels and Symptom Rating Following a Boxing Bout : Protocol for an Exploratory Randomized Trial

BACKGROUND: Head impacts are common in contact sports such as boxing and occur at times of elevated core body and brain temperatures induced by the exercise. Following impact, elevated brain temperature may lead to the development of exacerbated brain injury that can be monitored by blood biomarkers. Blood-brain biomarkers S100B and glial fibrillary acidic protein (GFAP) reflect glial injury; neur

Policy Verification in Stochastic Dynamical Systems Using Logarithmic Neural Certificates

We consider the verification of neural network policies for discrete-time stochastic systems with respect to reach-avoid specifications. We use a learner-verifier procedure that learns a certificate for the specification, represented as a neural network. Verifying that this neural network certificate is a so-called reach-avoid supermartingale (RASM) proves the satisfaction of a reach-avoid specifi

X-Ray Tomography Analysis of Damage Mechanisms in Metal Matrix Syntactic Foams During Compression

The aim of this study is to explore the internal damage mechanisms of AlSi12 metal matrix syntactic foam (MMSF) with embedded ceramic hollow spheres (CHSs) to understand the damage behavior during compressive loading. To achieve this goal, in situ synchrotron X-ray tomography is used. A qualitative and quantitative assessment of the initiation and gradual collapse of matrix, filler material, and p