Primary and secondary bile acids (BAs) influence metabolism and inflammation, and the gut microbiome modulates levels of BAs. We systematically explore the host genetic, gut microbial, and habitual dietary contribution to a panel of 19 serum and 15 stool BAs in two population-based cohorts (TwinsUK, n = 2,382; ZOE PREDICT-1, n = 327) and assess changes post-bariatric surgery and after nutritional

Machining-based deformation processing is used to produce metal foil and flat wire (strip) with suitable properties and quality for electrical power and renewable energy applications. In contrast to conventional multistage rolling, the strip is produced in a single-step and with much less process energy. Examples are presented from metal systems of varied workability, and strip product scale in te

Interfacial processes are involved in many areas of chemistry, physics and biochemistry, but following the structural changes of surfaces and thin films at relevant timescales remains challenging. Time-of flight neutron reflectometry can determine changes in surface composition and film thickness, but the speed of these measurements is typically limited by the neutron flux over the range of wavele

Human carbonic anhydrase II catalyzes the reversible reaction of carbon dioxide and water to form bicarbonate and a proton. His64-mediated proton shuttling between the active site and the bulk solvent is rate limiting. Here we investigate the protonation behavior of His64 as well as its structural and dynamic features in a pH dependent way. We derive two pK a values for His64, 6.25 and 7.60, that

We present an experimental study investigating the solvent-dependent dynamics of a 9,10-bis(phenylethynyl)anthracene monomer, dimer, and trimer. Using transient absorption spectroscopy, we have discovered that triplet excited state formation in the dimer and trimer molecules in polar solvents is a consequence of charge recombination subsequent to symmetry-breaking charge separation rather than sin

Kommunikatörsyrket inom offentlig sektor har på senare år varit på stark framväxt, men också i kraftig omvandling. Digitalisering, ökade förväntningar på organisationers kommunikation, en tilltagande medvetenhet i ledningen om kommunikationens strategiska betydelse, och alltmer komplexa verksamheter är några bakomliggande faktorer till den här utvecklingen. Det är också alltmer uppenbart att det s

The recent open letter from the Future of Life Institute (FLI) calling for a pause on the development of AI systems has generated a significant amount of discussion. We argue that more significant action to address the potential dangers of large, generative models, requires increased efforts on AI governance, and research funding structures to build a sustainable basis for transparent research on

Background: The number of people with cognitive impairment, including dementia, in the world is steadily increasing. Although the consumption of isoflavones and soy is associated with a reduced risk of cardiovascular disease, it might also be associated with cognitive impairment. The low number of studies investigating the association between soy/isoflavone intake and cognitive function warrant ad

Creating nutritious and ecologically regenerative food cultures depends on the local knowledge of food system laborers. Food producers in small island developing states center socioecological interdependence in their livelihoods and, as such, conserve biocultural diversity. Amid burgeoning health, economic, and climate crises brought on by colonialism, reclaiming food sovereignty requires a critic

In radiotherapy (RT), the treatment is thoroughly planned and optimized to fulfil the goal of delivering a high dose to the target, while sparing as much normal tissue as possible. This implies that the patient position and anatomy should be the same as they were during the planning image acquisition. To achieve this, it is important to have motion management methods for predicting, monitoring, an

Redogörelse för återtillsättandet av professuren i österländska språk vid Lunds universitet 1824 med fokus på ett återfunnet sakkunnigutlåtande från Matthias Norberg.

In this essay the media depictions of the funeral of the former Swedish prime minister Karl Staaff in 1915 are investigated. It shows that, in a pre-democratic state such as early twentieth-century Sweden, media events did not necessarily voice a hegemonic ideology or harmonious sense of community spirit. Rather, mediated public space, even at the commemoration of a former prime minister, could be

Redogörelse för tre tidigt kvinnodominerade yrkesutbildningar - för lärarinnor, sjuksköterskor och sjukgymnaster - vilka senare blivit universitetsämnen. Utgör del av den virtuella utställningen "150 år med kvinnor vid akademin".

Översiktlig presentation av Lunds universitets första 20 kvinnliga studerande under 1800-talet som grupp. Utgör del av den virtuella utställningen "150 år med kvinnor vid akademin".

Kort biografisk artikel om Lunds universitets första studentska. Utgör del av den virtuella utställningen "150 år med kvinnor vid akademin".