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Popular Abstract in Swedish Prostatacancer är den bland män vanligast förekommande cancerformen i Sverige. Under 2003 diagnostiserades 9882 nya fall. Sjukdomen drabbar framför allt äldre individer; många män är 70 år gamla eller äldre när de får diagnosen. Sjukdomsförloppet kan vara mycket varierande. Hos många är tumörtillväxten långsam, men sjukdomen kan också utvecklas snabbt. Många patienter lConcentrations of prostate-specific antigen (PSA) and human kallikrein 2 (hK2) were investigated in blood samples that had been obtained from men who were diagnosed with prostate cancer (PCa) decades later. The studies were based on a cohort comprising 22,444 men who, in 1974?1986, were early middle aged and represented a non-PCa-screened population. The results clearly demonstrate a very strong c

Context: SHBG regulates free sex steroid levels, which in turn regulate skeletal homeostasis. Twin studies have demonstrated that genetic factors largely account for interindividual variation in SHBG levels. Glucuronidated androgen metabolites have been proposed as markers of androgenic activity. Objective: Our objective was to investigate whether polymorphisms in the SHBG gene promoter [(TAAAA)(n

Background: Symptoms from the upper gastrointestinal tract are frequently encountered in clinical practice and may be of either organic or functional origin. For some of these conditions, according to the literature, certain management strategies can be recommended. For other conditions, the evidence is more ambiguous. The hypothesis that guided our study design was twofold: Management strategies

Popular Abstract in Swedish Avhandlingen syftar till att undersöka arbetslöshetens sociala konsekvenser och försöka ge en rimlig tolkning av variationer i arbetslöshetserfarenheter med hjälp av en teoretisk modell - ekonomi-skam modellen. Fokus ligger på att söka lyfta fram och visa på betydelsen av ekonomiska påfrestningar i kombination med skamupplevelser som en faktor för att förstå skillnader The purpose of this study has been to investigate the social consequences of unemployment and to give a possible interpretation of unemployment experiences through the application of the economy-shame model. It intends to put forward and show the significance of economic stress in combination with the feeling of shame as a factor important for the understanding of differences in unemploy-ment expe

An amino-terminal region of a, chain of type IV collagen noncollagenous domain [alpha(3)(IV)NC1] that induces experimental autoimmune glomerulortephritis (EAG) in rats has been identified. Only recombinant antigens that contain a nine-amino acid (AA) span of alpha(3)(IV)NC1, consistent with a T cell epitope, could induce EAG. It was hypothesized that synthetic peptides of this region should induce

When heating a dilute sample of the binary system of tetraethyleneglycol dodecyl ether (C12E4) and water from the micellar phase (L-1) into the two-phase region of a lamellar phase (L-alpha) and excess water (W) vesicles are formed. During heating, one passes a region of phase separation in the micellar phase (L-1' + L-1") where the initial micelles rapidly fuse into larger aggregates forming the

Three healthy young male subjects were given a single load of ethanol (approximately 3 g/kg body weight) over 5 hours. Liver aspiration biopsies were performed at the start of the experiment and 6, 14, 24, and 48 hours after the start. Blood alcohol and serum transaminase activity levels were measured simultaneously. Triglycerides and phospholipids of the liver biopsy material were determined by a

Acetals are efficiently hydrolyzed with silica gel‐supported pyridinium tosylate moistened with water in solvent‐free conditions under microwave irradiation. The method is efficient and mild, with acid‐sensitive 3‐hydroxyacetals and 3‐methoxyacetals being hydrolyzed in minutes in good yields.

In recent years it has been demonstrated that loud clicks generate short latency vestibular evoked myogenic potentials (VEMP). It has also been demonstrated that skull tap stimulation evokes similar VEMP. In the present study, the differences between the click-induced and the skull-tap induced VEMP were studied in 18 patients at onset of vestibular neuritis. Gentle skull taps were delivered manual