Sökresultat

Filtyp

Din sökning på "*" gav 536924 sökträffar

Correlations between cholinergic neurons and muscarinic m2 receptors in the rat retina

Acetylcholine is well established as the neurotransmitter of starburst amacrine cells in the vertebrate retina but their function is poorly understood. We compared the distribution of muscarinic m2 receptors in the rat retina with the localization of the starburst cell processes. mAChR2 immunoreactivity appeared in a central band in the inner plexiform layer, which did not co-localize with the pro

Dissolution state of cellulose in aqueous systems. 2. Acidic solvents

Cellulose is insoluble in water but can be dissolved in strong acidic or alkaline conditions. How well dissolved cellulose is in solution and how it organizes are key questions often neglected in literature. The typical low pH required for dissolving cellulose in acidic solvents limits the use of typical characterization techniques. In this respect, Polarization Transfer Solid State NMR (PT ssNMR)

PBX3 is a putative biomarker of aggressive prostate cancer

There is a great need to identify new and better prognostic and predictive biomarkers to stratify prostate cancer patients for optimal treatment. The aims of this study were to characterize the expression profile of pre-B cell leukemia homeobox (PBX) transcription factors in prostate cancer with an emphasis on investigating whether PBX3 harbours any prognostic value. The expression profile of PBX3

Patients' experiences of pain following day surgery - at 48 hours, seven days and three months

Recent studies indicate that patients experience pain after day surgery for a longer period than previously known. This requires verification. This was a prospective, descriptive correlational study. A convenience sample of 298 day surgery patients undergoing various surgical procedures was asked to report pain intensity and its interference with daily function 48 hours, seven days and three month

Så skapades en biskop : om etablerandet av Växjö stift

This article discusses the emergence of the episcopal see in Växjö. Contrary to previous research, which has been focused on written sources only, this article also discusses the archaeological record. The result implies that vivid connections between Scania, Denmark and southern Småland can be traced in the Late Iron Age and Early Middle Ages. This is shown by similarities in grave types, runic s

Dry sampling of gas-phase isocyanates and isocyanate aerosols from thermal degradation of polyurethane

The performance of a dry sampler, with an impregnated denuder in series with a glass fibre filter, using di-n-butylamine (DBA) for airborne isocyanates (200ml min-1) is investigated and compared with an impinger flask with a glass fibre filter in series (1 l min-1). An exposure chamber containing 1,6-hexamethylene diisocyanate (HDI), isophorone diisocyanate (IPDI), and 2,4- and 2,6-toluene diisocy

Neck and upper extremity pain in sonographers – Associations with occupational factors

Sonographers have a high risk of musculoskeletal disorders. This study explores the associations between working conditions and musculoskeletal pain based on the frequency and intensity of pain in the neck and upper extremities. A questionnaire was answered by 291 female sonographers. High prevalence of neck/shoulder pain was associated with eye complaints and headache related to work on the compu

Determination of aromatic amines in aqueous extracts of polyurethane foam using hydrophilic interaction liquid chromatography and mass spectrometry

A method is presented for the determination of aromatic amines in aqueous extracts of polyurethane (PUR) foam. The method is based on the extraction of PUR foam using aqueous acetic acid (0.1%, w/v) followed by determination of extracted aromatic amines using hydrophilic interaction liquid chromatography (HILIC) and tandem mass spectrometry (MS/MS) with positive electrospray ionisation. The inject

Symptoms following day surgery : A review of the literature

Aim: The purpose of this paper is to provide a broad-based overview of the current literature regarding patients' experiences of symptoms following day surgery. Background: The advent of new anaesthetic and anti-emetic agents, advanced surgical techniques and the need for reduced costs for inpatient hospital services, has resulted in about 70% of all surgical procedures being undertaken as day sur

Enzyme flow immunoassay using a Protein G column for the screening of triazine herbicides in surface and waste water

A method for screening of triazine herbicides in surface and waste water is presented. The method is based on an enzyme flow immunoassay (EFIA) for the detection of the free fraction of a horse radish peroxidase (HRP)-labelled antigen (tracer). This was accomplished by trapping the bound tracer fraction in a Protein G column, allowing the residual free tracer fraction to pass and be detected spect

A new high-resolution Holocene tephra stratigraphy in eastern Iceland : Improving the Icelandic and North Atlantic tephrochronology

A new and improved Holocene tephra stratigraphy and tephrochronological framework for eastern and northern Iceland is presented. Investigations of a sediment sequence from Lake Lögurinn have revealed a comprehensive tephra record spanning the last 10.200 years. A total of 157 tephra layers have been identified, whereof 149 tephra layers have been correlated to its source volcanic system using geoc

Screening for infantile colic and parents experiences of simethicone and probiotics: a quantitative, descriptive sub-study.

Background Colic affects at least 10% of newborns and parents seek help. The aim of this study was to present why infants whose parents sought help for colic, where not included in two colic trials and to describe the use and perceived effect of simethicone and probiotics amongst those infants who were included. Method A quantitative, descriptive sub-study based on unpublished data collected in

Occupational balance : A scoping review of current research and identified knowledge gaps

This article reports a comprehensive review of the research conducted regarding occupational balance. A scoping study method was used to explore and describe current research about occupational balance and to identify research gaps. Twenty-two articles published between 2009 and 2014 met the inclusion criteria. The articles reported studies conducted in eight countries on four continents, but the

Spatiotemporal variability in carbon exchange fluxes across the Sahel

Semi-arid regions play an increasingly important role as a sink within the global carbon (C) cycle and is the main biome driving inter-annual variability in carbon dioxide (CO2) uptake by terrestrial ecosystems. This indicates the need for detailed studies of spatiotemporal variability in C cycling for semi-arid ecosystems. We have synthesized data on the land-atmosphere exchange of CO2 measured w

Effect of the dispersed state of phospholipids on emulsification—Part 1. Phosphatidylcholine

In this study the effect of the dispersed state of soy phosphatidylcholine on emulsification is investigated. The emulsifier is either dispersed in the aqueous phase (coarsely, as small vesicles, as large vesicles), or it is dispersed in the oil phase. Oil-in-water emulsions are prepared with the emulsifier present in the different dispersed states. High-pressure homogenization is used for the emu

Chondrocytes derived from mesenchymal stromal cells and induced pluripotent cells of patients with familial osteochondritis dissecans exhibit an endoplasmic reticulum stress response and defective matrix assembly

Familial osteochondritis dissecans (FOCD) is an inherited skeletal defect characterized by the development of large cartilage lesions in multiple joints, short stature, and early onset of severe osteoarthritis. It is associated with a heterozygous mutation in the ACAN gene, resulting in a Val-Met replacement in the C-type lectin domain of aggrecan. To understand the cellular pathogenesis of this c

Elucidating the Molecular Composition of Cartilage by Proteomics

Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins with guanidine-HCl. However, an unextracted collagen-rich residual is left after extraction. In addition, the high abundance of anionic polysaccharide molecules extracted from cart

Selective extraction of small proteins from biological samples using a novel restricted access column with cation exchange properties

The determination of proteins utilising a polymer-based restricted access support material with ion exchange properties (IERAM) is outlined. Solid phase extraction coupled on-line with a microbore reversed phase HPLC system for the quantitation of small marker proteins is demonstrated. The cation-exchange restricted access packings were characterised with respect to their adsorption and desorption

Development of fluorescence based flow immunoassays utilising restricted access columns

The development of high-speed flow immunoassay techniques is described. The principles are based on heterogeneous flow immunoassay interactions. High sample throughput can be used for screening small analytes in a number of biological matrices originating from samples of water from environmentally polluted areas, or biological fluids such as urine and plasma. The immunochemical detection principle