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Loss of the smooth muscle contractile phenotype is critical in atherosclerosis and in restenosis after angioplasty, but its early signals are incompletely understood. In this study, we have explored the role of transient receptor potential canonical (TRPC) proteins, which have been suggested to mediate store-operated Ca2+ entry (SOCE). Contractility of rat cerebral arteries in organ culture is pre

Abstract not available.

Materials and Methods: Monophasic action potential (MAP) were recorded, using the CARTO mapping system and NaviStar catheters, during sinus rhythm from the endocardium at 43 ± 15 LV or RV sites in 8 patients, at 61 ± 18 LV and/or RV sites in 10 pigs and during atrial pacing from the endo- and epicardium at 211 ± 54 LV and RV sites in additional 10 pigs. Local activation time (AT), MAP duration (MA

A search for sleptons, neutralinos, charginos, sgoldstinos and heavy stable charged sleptons in the context of scenarios where the lightest supersymmetric particle is the gravitino, is presented. Data collected during 2000 with the DELPHI detector at centre-of-mass energies from 204 to 208 GeV were analysed and combined with all the data collected from 1995 to 1999 at lower energies. No evidence f

The pK(a) of a C-13-enriched fatty acid probe, tetradecanoic acid, was investigated in a variety of sugar-derived (APG) surfactants by using C-13 NMR to monitor the chemical environment of the probe during titration with base. There was an increase of approximately 2 pK(a) units for the probe within the micellar systems compared to the value of acetic acid in water. Analysis shows that the interfa

Objective: Norepinephrine (NE) is elevated in pregnancies complicated by preeclampsia (PE). Specific uptake of NE by the NE transporter (NET) plays a central role as regulator of NE levels. Expression of NET is reduced in placentas from PE pregnancies. To study adverse fetal effects of reduced NET expression on the placental buffering capacity, the NET was pharmacologically blocked by a specific u

Purpose: Free prostate specific antigen (PSA) in serum consists of heterogeneous molecular subforms. Recently we developed an immunoassay for selective measurement of a subfraction of free PSA called intact PSA, which has been shown to be closely associated with prostate cancer. We assessed the ability of serum intact PSA to discriminate between benign and malignant prostatic disease. Materials an

Popular Abstract in Swedish Cafeterian i Malmö Musikhögskola förvandlas två gånger om året till de passionerades mötesplats: När terminens ”Gambiastudenter” återvänder efter sina tre veckors fältarbete och skola med palmer som klassrumsväggar, möts de av veteranerna, de som redan varit där och som förstår att tolka entusiasmen. Det handlar inte om den vitalitet som alstrats av solen, färgerna och The present study seeks to examine attitudes to teaching and learning among jalis in the Gambia. Although this is the main focus, the horizon of which the study is carried out, analysed and discussed, is the development of music teacher education in Sweden during the last three decades, and of which I have been a participant. The intention of the study is to expand current views on music teaching

The risk of seizure recurrence within the first year of life was evaluated in infants with neonatal seizures diagnosed with a combination of clinical signs, amplitude-integrated electroencephalogram (EEG) monitoring, and standard EEG. Fifty eight of 283 (4.5%) neonates in tertiary level neonatal intensive care had seizures. The mortality in the infants with neonatal seizures was 36.2%. In 31 survi

A number of screening procedures are offered by midwives during pregnancy and the number is increasing rapidly. The measurement of nuchal translucency is a fairly new ultrasound method for antenatal screening, primarily for Down syndrome. The results give a better risk calculation than maternal age alone and can mean a decrease in the number of invasive procedures needed to identify this syndrome

The possibilities for implementing a rainwater collection system in Ringdansen, a residential area in Norrkoping, Sweden, have been explored by analysing four scenarios for using rainwater in a dual water supply system to supplement drinking water. A computer model has been generated to quantify the water saving potential of the rainwater collection scheme. The performance of the rainwater system

Signaling mechanisms for stretch-dependent growth and differentiation of vascular smooth muscle were investigated in mechanically loaded rat portal veins in organ culture. Stretch-dependent protein synthesis was found to depend on endogenous release of angiotensin II. Autoradiography after [35S]methionine incorporation revealed stretch-dependent synthesis of several proteins, of which SM22 and act

BACKGROUND: RBCs of the Hy- phenotype have, in the past, been typed as Gy(a+(w)), Hy-, Jo(a-), and RBCs with the Jo(a-) phenotype type Gy(a+), Hy-(w), and Jo(a-). Anti-Hy and anti-Jo(a) are difficult to identify mainly because appropriate reagent R6Cs are poorly characterized. Historically, anti-Jo(a) has not reacted with RBCs with either phenotype. This report describes a case of an anti-Jo(a) th

The influence of the auxotrophic deficiencies of the host strain and expression vector selection on the production of a heterologous protein was investigated. Heterologous xylanase production by two prototrophic S. cerevisiae transformants, containing either a plasmid-based, YEp-type expression system or an integrative, YIp-type expression system, were compared with production by an auxotrophic tr

A technique to estimate fungal growth rates in field samples was tested in soil. The technique is based on the addition of C-14-acetate to a soil slurry and the subsequent uptake and incorporation of the labelled acetate into the fungus specific substance ergosterol by the fungi. The addition of fungal inhibitors decreased acetate incorporation rates, while bacterial inhibitors did not. Fungus-fre