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2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases

To update the European League Against Rheumatism (EULAR) recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD) published in 2011. Four systematic literature reviews were performed regarding the incidence/prevalence of vaccine-preventable infections among patients with AIIRD; efficacy, immunogenicity and safety of vaccines; effect of anti-rheumati

Wood decay fungus Flavodon ambrosius (Basidiomycota: Polyporales) is widely farmed by two genera of ambrosia beetles

The ambrosia fungus Flavodon ambrosius is the primary nutritional mutualist of ambrosia beetles Ambrosiodmus and Ambrosiophilus in North America. F. ambrosius is the only known ambrosial basidiomycete, unique in its efficient lignocellulose degradation. F. ambrosius is associated with both native American beetle species and species introduced from Asia. It remains unknown whether F. ambrosius is s

An Ecology of Measures and Indicators: Bibliometrics in Resource Allocation

This chapter briefly reviews how bibliometric indicators are used for allocating resources in academia. How these measures can be understood in relation to different evaluation systems is discussed, and various types of applications - including individual level use - are outlined. Furthermore, attention is given to the effect of evaluation in terms of incentives and possible adverse effects. The i

Idas nya teleskop

Ida har fått ett nytt teleskop av sin farfar och vill nu lära sig använda den. Hon och hennes kusin Malin träffar Sara och Hanna en vacker stjärnklar kväll och får lära känna natthimmeln. När de har lärt sig hitta på natthimmeln lyckas de leta upp planeter, nebulosor och galaxer.Ida has a received a new telescope from her grandfather and now she wants to learn how to use it. She meets up with Malin, Sara and Hanna late at night and together they learn to navigate the night sky and locate some planets, nebulae and galaxies.

Incorporating Cultural Diversity, Nation Building and Social Cohesion When Teaching Communication and Relationship Management

The purpose of this chapter is to reflect on the necessity of incorporating practical and experiential learning modalities in higher education to prepare communication and relationship management students for engaging others in potentially conflicting socio-cultural heterogeneous settings. It is argued that cultural diversity sensitivity, cultivated in teaching modalities, could enhance social coh

Mimicry and artistry: Place branders' construction of "good" branding

Many public organizations think of themselves as brands and engage in branding to increase their attractiveness. Often this is seen as a good practice, but this paper takes a more skeptical view and interrogates the value of place branding expertise for public organizations. Through observation of a place branding conference, drawing on some principles from ethnomethodology, this paper provides cl

The Fiscal State in Africa: Evidence from a century of growth

Why do large differences in fiscal capacity exist between states in the Global South? We constructa comprehensive new dataset of tax and revenue collection for 46 African polities from 1900 to2015. Descriptive analyses show that many polities in Africa have been characterized by stronggrowth in real tax collection. As a next step, we employ these data to test theories of fiscal capac-ity in a long

Arrayed molecular barcoding of leukemic stem cells

Functional screens on cancer cells using compound or protein libraries are usually performed in vitro. However, to assess the effects on leukemia stem cells (LSCs) in a screening setting, methodologies that allow for a high-throughput in vivo readout of leukemia-initiating activity are needed. One experimental approach to solve this issue is to genetically label, also referred to as “barcoding,” t

Cities and Consumption: Sharing cities and achieving the sustainable development goals

In October 2019, over 200 people from around the world gathered at the Sharing Cities Summit in Sweden for a conference in Lund and an exhibition and workshops in Malmö. The combination of people from municipalities, academia, sharing initiatives, NGOs and SMEs created a vibrant environment for critical discussions. The focus of the event was centered on the connections between the Sustainable Dev

The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable α-Retaining and β-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila

Enzymes active on glycosidic bonds are defined according to the stereochemistry of both substrates and products of the reactions they catalyze. The CAZy classification further assigns these enzymes into sequence-based families sharing a common stereochemistry for substrates (either α- or β-) and products (i.e., inverting or retaining mechanism). Here we describe the N-acetylgalactosaminidases AmGH

Introducing patient-reported outcome in the acute leukemia quality registries in Sweden

Objectives: The use of patient-reported outcome (PRO) measured outside clinical trials is not well defined. We report the first analysis of the prospective PRO study within the Swedish acute myeloid leukemia (AML) and the acute lymphoblastic leukemia (ALL) registries. Methods: PRO was requested 6 months after diagnosis. The EORTC Quality of life Questionnaire Core 30-item, the Patient Health Quest

MOCCA-SURVEY Database I : Dissolution of tidally filling star clusters harboring black hole subsystem

We investigate the dissolution process of star clusters embedded in an external tidal field and harboring a subsystem of stellar-mass black hole. For this purpose we analyzed the MOCCA models of real star clusters contained in the Mocca Survey Database I. We showed that the presence of a stellar-mass black hole subsystem in tidally filling star cluster can lead to abrupt cluster dissolution connec

Social innovation in worker co-operatives: a cross-comparative research between Argentinian and British cases

The Social and Solidarity Economy (SSE) have proved to combat inequalities, neoliberal policies, and ultimately, counteract the hegemonic economic rationale imposed by the market (Gaiger 2007). In particular, co-operatives are engaged in some market activity, although the economic principle does not prevail over the social objectives of the organisation. Indeed, this is the core of the social inno

Towards a Circular Photovoltaic Economy: The Role of Service-based Business Models

Solar photovoltaics (PV) has experienced tremendous market growth and has large potential in the urgently needed transition towards a low-carbon energy system. The continued growth of the sector will, however, evoke new sustainability challenges with regard to efficient material use as well as end-of life management of PV products. The aim of this paper is to provide an overview of potential Circu

The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry

We have characterized and compared the structures of ergosterol- and cholesterol-containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes before and after interaction with the amphiphilic antifungal drug amphotericin B (AmB) using neutron reflection. AmB inserts into both pure POPC and sterol-containing membranes in the lipid chain region and does not significantly perturb the