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Properties of bilateral spinocerebellar activation of cerebellar cortical neurons.

We aimed to explore the cerebellar cortical inputs from two spinocerebellar pathways, the spinal border cell-component of the ventral spinocerebellar tract (SBC-VSCT) and the dorsal spinocerebellar tract (DSCT), respectively, in the sublobule C1 of the cerebellar posterior lobe. The two pathways were activated by electrical stimulation of the contralateral lateral funiculus (coLF) and the ipsilate

Ubiquitous Structural Signaling in Bacterial Phytochromes.

The phytochrome family of light-switchable proteins has long been studied by biochemical, spectroscopic and crystallographic means, while a direct probe for global conformational signal propagation has been lacking. Using solution X-ray scattering, we find that the photosensory cores of several bacterial phytochromes undergo similar large-scale structural changes upon red-light excitation. The dat

Ohlin on the Great Depression : Ten Newspaper Articles 1929–1935

Bertil Ohlin was a most active commentator on current economic events in the interwar period, combining his academic work with a journalistic output of an impressive scale. He published more than a thousand newspaper articles in the 1920s and 1930s, more than any other professor in economics in Sweden. Here we have collected 10 articles by Ohlin, translated from Swedish and originally published i

EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis

Objective To develop evidence-based recommendations on the use of imaging of the joints in the clinical management of rheumatoid arthritis (RA). Methods The task force comprised an expert group of rheumatologists, radiologists, methodologists and experienced rheumatology practitioners from 13 countries. Thirteen key questions on the role of imaging in RA were generated using a process of discussio

Kompendium i aktiva system - detektion

The following document is used in the course Fire detection and suppression, which is given by the Department of Fire Safety Engineering at Lund University. In the first part of this document a short review of typical fire signatures, namely radiation, fire effluent gases, aerosol particles, temperature and sound is presented. Subsequent chapters include information about fire detectors, fire alar

Functionally Relevant Interplay between the Fe(4)S(4) Cluster and CN(-) Ligands in the Active Site of [FeFe]-Hydrogenases.

[FeFe]-hydrogenases are highly efficient H(2)-evolving metalloenzymes that include cyanides and carbonyls in the active site. The latter is an Fe(6)S(6) cluster (the so-called H-cluster) that can be subdivided into a binuclear portion carrying the CO and CN(-) groups and a tetranuclear subcluster. The fundamental role of cyanide ligands in increasing the basicity of the H-cluster has been highligh

Overcoming Drug Resistance and Treating Advanced Prostate Cancer.

Most of the prostate cancers (PCa) in advanced stage will progress to castration-resistant prostate cancer (CRPC). Within CRPC group, 50-70% of the patients will develop bone metastasis in axial and other regions of the skeleton. Once PCa cells spread to the bone, currently, no treatment regimens are available to eradicate the metastasis, and cancer- related death becomes inevitable. In 2012, it i

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The indigenista novel is a realistic novel with a strongly ideological character that was developed primarily in the Andean countries (Peru, Bolivia, Ecuador) during the first half of the 20th century with the purpose of making the reader aware of the living conditions of the indigenous Native American population. The overall aim of this study was to investigate the female characters in five of th

On the Stability of the Nystrom Method for the Muskhelishvili Equation on Contours with Corners

The stability of the Nystrom method for the Muskhelishvili equation on piecewise smooth simple contours Gamma is studied. It is shown that in the space L-2 the method is stable if and only if certain operators A tau(j) from an algebra of Toeplitz operators are invertible. The operators A tau(j) depend on the parameters of the equation considered, on the opening angles theta(j) of the corner points

Wild Skylarks Seasonally Modulate Energy Budgets but Maintain Energetically Costly Inflammatory Immune Responses throughout the Annual Cycle

A central hypothesis of ecological immunology is that immune defences are traded off against competing physiological and behavioural processes. During energetically demanding periods, birds are predicted to switch from expensive inflammatory responses to less costly immune responses. Acute phase responses (APRs) are a particularly costly form of immune defence, and, hence, seasonal modulations in

Sven Snogerup – ett liv med botaniken

En av Sveriges ledande botanister har gått ur tiden. Sven Snogerup (1929-2013), hedersmedlem i Svenska Botaniska Föreningen sedan 1999, porträtteras här av Ingvar Kärnefelt.

Area-aggregated assessments of perceived environmental attributes may overcome single-source bias in studies of green environments and health: results from a cross-sectional survey in southern Sweden

Background: Most studies assessing health effects of neighborhood characteristics either use self-reports or objective assessments of the environment, the latter often based on Geographical Information Systems (GIS). While objective measures require detailed landscape data, self-assessments may yield confounded results. In this study we demonstrate how self-assessments of green neighborhood enviro

The Contribution of Vegetation and Landscape Configuration for Predicting Environmental Change Impacts on Iberian Birds

Although climate is known to be one of the key factors determining animal species distributions amongst others, projections of global change impacts on their distributions often rely on bioclimatic envelope models. Vegetation structure and landscape configuration are also key determinants of distributions, but they are rarely considered in such assessments. We explore the consequences of using sim

Retinopathy in subjects with pre-diabetes and electrophysiological studies in diabetes patients with and without retinopathy

Diabetes is increasing worldwide and hence the risk developing complications where retinopathy is the theme of this study. The aim of the study was to evaluate the presence of (vascular) retinopathy in subjects with the pre-diabetes stage, impaired fasting glucose (IFG), and the development of retinopathy in these subjects during five years. In the second part of the study diabetes patients with d

Welfare as a means for political stability : a law and society analysis

There have been extensive discussions in academic circles of why some countries develop into welfare states while others do not. Two main factors mentioned in these discussions are economic growth and the need for political stability. In these discussions, the example of Sweden, where the welfare state allegedly emerged from a ‘culture of consensus’, has often been treated as an historic exception

Enhancement of fermentable sugar yield by competitive adsorption of non-enzymatic substances from yeast and cellulase on lignin

Background: Enhancement of enzymatic digestibility by some supplementations could reduce enzyme loading and cost, which is still too high to realize economical production of lignocellulosic biofuels. A recent study indicates that yeast hydrolysates (YH) have improved the efficiency of cellulases on digestibility of furfural residues (FR). In the current work, the components of YH were separated by

Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn.

Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It may be treated with either needle aspiration or insertion of a chest tube. The former consists of aspiration of air with a syringe through a needle or an angiocatheter, usually through the second or third intercostal space in the midclavicular line.

Carbonate formation on p(4 x 4)-O/Ag(111)

High-resolution core-level spectroscopy and density-functional theory calculations have been used to investigate CO adsorption on the p(4 x 4) structure of oxidized Ag(111). CO adsorption with subsequent carbonate formation was observed at 100 K. The experimental results are consistent with calculations that reveal low activation barriers to form CO2 and CO32- from adsorbed CO. On the basis of a g

Comparing wine-based and beer-based baits for moth trapping: a field experiment

Vid fångst av nattfjärilar använder man ofta lockbeten. De består av en trasa eller liknande som dränks in med någon lockande vätska och hängs upp i t.ex. ett träd. Under natten kan betet inspekteras många gånger och djur samlas in. Recepten för den lockande vätska varierar kraftigt mellan olika samlare men innehåller alltid jästa produkter av något slag. En stor skiljelinje går mellan beten som b