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Kapitlet fokuserar på barn i familjer som sökt asyl i Sverige. Med en utvecklingspsykologisk utgångspunkt adresseras barnens situation och konsekvenserna för deras utveckling och välbefinnande av ett otillräckligt skydd och stöd. Med ett rättighetsbaserat perspektiv diskuteras barnens folkrättsliga skydd samt hur detta upprätthålls i Sverige. Vi avslutar med en reflektion kring prioriteringar fram
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BACKGROUND: Patients receiving intraoperative ventilation during general anesthesia often have low end-tidal CO2 (etCO2). We examined the association of intraoperative etCO2 levels with the occurrence of postoperative pulmonary complications (PPCs) in a conveniently-sized international, prospective study named 'Local ASsessment of Ventilatory management during General Anesthesia for Surgery' (LAS
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IMPORTANCE: Robot-assisted surgery (RAS) is increasingly used for abdominal procedures; however, postoperative pulmonary complications (PPCs) are more frequent in patients undergoing RAS compared with patients undergoing conventional laparoscopic surgery (CLS).OBJECTIVE: To compare the incidence of PPCs after CLS and RAS and to determine which patient-, surgery-, and anesthesia-related factors are
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Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperativ
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The demographic development suggests a dramatic growth in the number of elderly patients undergoing surgery in Europe. Most red blood cell transfusions (RBCT) are administered to older people, but little is known about perioperative transfusion practices in this population. In this secondary analysis of the prospective observational multicentre European Transfusion Practice and Outcome Study (ETPO
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BackgroundIt is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events.MethodsPos
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Background: The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption due to COVID-19.Methods: A global expert response study was conducted to elicit projections for the proportion of elective surgery that would be cancelled or postponed during t
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Inequalities between Dirichlet and Neumann eigenvalues of the Laplacian and of other differential operators have been intensively studied in the past decades. The aim of this paper is to introduce differential forms and the de Rham complex in the study of such inequalities. We show how differential forms lie hidden at the heart of the work of Rohleder on inequalities between Dirichlet and Neumann
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BackgroundThe aim of this analysis is to determine geo–economic variations in epidemiology, ventilator settings and outcome in patients receiving general anesthesia for surgery.MethodsPosthoc analysis of a worldwide study in 29 countries. Lower and upper middle–income countries (LMIC and UMIC), and high–income countries (HIC) were compared. The coprimary endpoint was the risk for and incidence of
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Poor postoperative outcomes following colon cancer (CC) resection are influenced by multiple factors, including both patient-related characteristics as well as surgeon-related factors. However, the influence of surgical specialization, surgeon resection volume and surgeon gender on patient’s postoperative out- come, after complex procedures such as emergency CC resection, remains incompletely unde
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Judging an individual’s loyalty in security-sensitive roles is a high-stakes task, yet little is known about the extent and sources of variability in such judgments. This study examined how 58 participants with experience in personnel security assessment evaluated applicant profiles connected to five different countries. Each participant reviewed five protocols and judged whether the case containe
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STUDY OBJECTIVE: Male sex has inconsistently been associated with the development of postoperative pulmonary complications (PPCs). These studies were different in size, design, population and preoperative risk. We reanalysed the database of 'Local ASsessment of Ventilatory management during General Anaesthesia for Surgery study' (LAS VEGAS) to evaluate differences between females and males with re
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BACKGROUND: Homologous recombination deficiency (HRD) originating from inactivation of genes like BRCA1/BRCA2 is a targetable abnormality common in triple-negative breast cancer (TNBC). In estrogen-receptor (ER)-positive HER2-negative (ERpHER2n) breast cancer (BC), HRD prevalence and clinical impact are unclear.METHODS: We analyzed 502 ERpHER2n tumors from patients recruited via the population-rep
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BackgroundMolecular subtypes of lung adenocarcinoma (LUAD) with varying prognosis and characteristics have been proposed based on one or two-dimensional studies but are not yet implemented into clinical routine. Epigenetic modifications in cancer cells are independent of sequence variants, directly linked to gene and genome regulation, and thus provide important information to guide subclassificat
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The sharing economy generates many benefits for cities and their citizens. However, it also causes numerous economic, social and environmental challenges, which are the reasons cities develop various policies and regulations. Previous research has explored municipal regulations across cities and countries but often overlooked alternative governance mechanisms. Our earlier work highlighted the need
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As the impact of climate change intensifies, there is an urge to adapt Swedish residential buildings with a special focus on improving their energy efficiency and resilience. In this study, adaptive strategies through Artificial Intelligence and Reinforcement Learning will be provided for the energy management of different Swedish residential buildings. The aim will be the optimization of energy u
