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In recent years the market for biopharmaceutical products has been increasing rapidly as a result of an increased demand for new and efficient treatments of various indications. Biopharmaceuticals are distinguished from chemical drugs by being derived from a biological origin and are hence, frequently constituting biological macromolecules. With the emergence of recombinant DNA technology, today m

Abstract not available

The subgraph homeomorphism problem is to decide whether there is an injective mapping of the vertices of a pattern graph into vertices of a host graph so that the edges of the pattern graph can be mapped into (internally) vertex-disjoint paths in the host graph. The restriction of subgraph homeomorphism where an injective mapping of the vertices of the pattern graph into vertices of the host graph

Utgångspunkten för denna studie har varit studenten och dennes motivation för att lära och förbereda sig inför ett yrkesliv som civilingenjör. Vi konstaterar att man i planering och genomförande av en kurs bör ta hänsyn till de olika behov som finns hos studenten, läraren, lärarteamet, avdelningen/institutionen, andra kurser, universitetet och dess uppdragsgivare, samt näringslivet och samhället i

Popular Abstract in Swedish Bakgrund Coeliaki eller glutenenteropati (GE) är beteckningar på ett så kallat malabsorptionstillstånd, dvs ett tillstånd med brister (som kan omfatta bl a B-vitaminer, järn och kalk) och/eller diarré till följd av inflammation i tarmen. Vid GE sitter inflammationen i slemhinnan i början av tunntarmen. GE omnämndes första gången av Araeteus i Rom 2:a århundradet efter The prevalence of coeliac disease (CD) was initially estimated to 1/1537. Based on serial analysis [GA and endomysial antibodies (EMA)], the prevalence was 6/1970 (0.30%). In autoimmune chronic hepatitis 5.4% and in IDDM 2.6% had CD, why regular screening for CD in these conditions seems motivated. The frequency of IgA-GA positivity was increased in alcoholic liver disease, PBC, primary sclerosin

Tumor cells often carry mutations in genes that control cell survival, and become resistant to signals that trigger cell death. Yet, some cell death pathways remain intact in tumor cells. If identified, these pathways might be exploited to selectively remove tumor cells. HAMLET (human α-lactalbumin made lethal to tumor cells) is a protein-lipid complex derived from human milk that activates cell d

A new method for Euclidean reconstruction from sequences of images taken by uncalibrated cameras, with constant intrinsic parameters, is described. Our approach leads to a variant of the so called Kruppa equations. It is shown that it is possible to calculate the intrinsic parameters as well as the Euclidean reconstruction from at least three images. The novelty of our approach is that we build ou