OBJECTIVE: To evaluate the effects of the neurological "wake-up test" (NWT), defined as interruption of continuous propofol sedation and evaluation of the patient's level of consciousness, on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in patients with severe subarachnoid hemorrhage (SAH) or traumatic brain injury (TBI).METHODS: A total of 127 NWT procedures in 21 severely br

To investigate the prevalence, distribution, and colonization burden of Staphylococcus aureus (S. aureus) and MRSA in different body sites among people who inject drugs (PWID) and compare it to a control group consisting of non-injectors. In this cross-sectional survey, 49 active PWID from the needle exchange program (NEP) in Malmö, Sweden, and 60 non-injecting controls from an emergency psychiatr

Min avhandling handlar om hur barns medfödda temperamentsegenskaper påverkar deras risktagande. Temperamentsegenskaper antas avspegla aktiviteten i biologiskt nedärvda motivationssystem. Aktiviteten i dessa avgör hur snabbt, hur starkt och hur länge vi kommer att reagera i olika situationer. I vår första studie ville vi studera psykometriska egenskaper hos det frågeformulär vi avsåg att använda i This thesis concerns temperamental qualities and their influence on risk-taking behavior during middle childhood (7–11 years of age). Contemporary research generally agrees upon the notion that temperament constitutes two motivational systems, sensitive to punishment and reward respectively, together with a third system that is responsible for regulating the motivational systems. Risk-taking is ge

Purpose: It has been proposed that biological/chemical substances in the intestine might play a role in the occurrence and deterioration of perianal fistulas. Elimination of such unidentified factors from the lower gastrointestinal tract might offer a new strategy for the management of anal fistulas. The aim of this study was to evaluate the clinical effects on non-Crohn’s disease perianal fistula

Homelessness as a political and social dominion has a number of features that make it particularly difficult to tackle. In addition to being a wicked problem, homelessness offers several analytical avenues. How do these characteristics affect the evaluation of programmes and projects aspiring to combat homelessness? Dissimilar pictures and solutions regarding homelessness in the US and in European

The supported liquid membrane technique offers new possibilities for analytical enrichment, field sampling and speciation. The possibility of using the technique for the enrichment of metals in a flow system with off-line atomic absorption spectrometry in the final analysis step is outlined. Five metals (Cu, Cd, Co, Ni and Zn) have been used as model substances and different approaches to transpor

The aim of this study was to explore whether brain-derived neurotrophic factor (BDNF) can improve neuronal survival in cell cultures of rat dentate gyrus subjected to a hypoglycaemic insult. Glucose deprivation for 15 h caused severe neuronal loss (about 70%). BDNF added either 24 h before or 4 h after onset of hypoglycaemia completely protected granule cells against this insult-induced damage. Ne

Fossil fuel subsidy reform has in recent years been addressed by international economic organizations including the International Monetary Fund (IMF) and the Organisation for Economic Co-operation and Development (OECD). The two organizations have differed significantly in how they define fossil fuel subsidies. The IMF’s definition constitutes a radical break with previous definitions by including

With the introduction of market reforms in the public sector, a set of rules becomes applicable to keep governments from distorting competition. This study discusses the impact of three such competition rules on Swedish government – EU rules on State aid and public procurement, as well as the Swedish rules on anti-competitive sales activities. Together they set the conditions for how governments c

The mechanisms that specify photoreceptor cell-fate determination, especially as regards to short-wave-sensitive (S) versus medium-wave-sensitive (M) cone identity, and maintain their nature and function, are not fully understood. Here we report the importance of general transcription factor II-I repeat domain-containing protein 1 (GTF2IRD1) in maintaining M cone cell identity and function as well

Withania somnifera Dunal (Indian Ginseng) has recently been shown to impair ethanol self-administration. In order to gain further insights on the ability of the Withania somnifera standardised root extract (WSE) to affect the motivational properties of ethanol, this study investigated whether WSE may also affect ethanol (2 g/kg)-elicited conditioned place preference (CPP) and aversion (CPA). To th

The MAX IV laboratory is a Swedish national laboratory for synchrotron radiation hosted by the Lund University. It will operate two storage rings to produce synchrotron light of very high intensity and quality over a broad wavelength range. A linear accelerator will feed these storage rings in topping up mode as well as serve as an electron source for a short pulse facility built on its extension.

Ultrafast extreme-ultraviolet (XUV) and X-ray sources are revolutionizing our ability to follow femtosecond processes with ångström-scale resolution. The next frontier is to simultaneously control the direction, duration and timing of such radiation. Here, we demonstrate a fully functional opto-optical modulator for XUV light, similar to modulators available at infrared (IR) and visible wavelength

We have characterized the dissolved state of microcrystalline cellulose (MCC) in cold alkali [2.0 M NaOH(aq)] solutions using a combination of small angle X-ray (SAXS) and static light scattering (SLS), (Formula presented.)H NMR, NMR self-diffusion, and rheology experiments. NMR and SAXS data demonstrate that the cellulose is fully molecularly dissolved. SLS, however, shows the presence of large c

This paper investigates the effect of international research visits on promotion. Research visits may help to expand existing networks and promote knowledge transfer while at the same time ensuring career stability, identified as the main barrier to mobility in Europe and Japan. Using a dataset of 370 bioscience professors in Japan we find that international research visits have a positive effect