In this paper we consider a one-warehouse N-retailer inventory system characterized by access to real-time point-of-sale data, and a time based dispatching and shipment consolidation policy at the warehouse. More precisely, inventory is reviewed continuously, while a consolidated shipment (for example, a truck) to all retailers is dispatched from the warehouse at regular time intervals. The focus

The effect of adding soy protein on the texture and colour of garri, a West African cassava food, is evaluated. Garri is mostly pre-gelatinized and agglomerate starch product. The challenge lies in maximizing the protein supplementation without changing the textural characteristics. Three different soybean flours were used for fortification: toasted soy flour (TSF), isolated soy protein (ISP) and

Objective: Negative pressure wound therapy (NPWT) is a recently introduced treatment modality for post-sternotomy mediastinitis. The aim of this study was to compare the mortality rate, the sternal re-infection rate and the length of hospital stay in patients with post-sternotomy mediastinitis after NPWT and conventional treatment. Methods: We retrospectively analysed 118 patients with post-sterno

We propose and analyze a high-fidelity readout scheme for a single-instance approach to quantum computing in rare-earth-ion-doped crystals. The scheme is based on using different elements as qubit and readout ions, where the readout ions are doped into the material at a much lower concentration than the qubit ions. It is shown that by allowing the qubit ion sitting closest to a readout ion to act

We have performed a systematic study of the entropy term in the MM/GBSA (molecular Mechanics combined with generalized Born and surface area solvation) approach to calculate ligand-binding affinities The entropies are calculated by a normal mode analysis of harmonic frequencies from minimized snapshots of molecular dynamics simulations. For computational reasons, these calculations have normally b

New Zealand is often seen as a leader when it comes to environmental policies, but it needs to do much more to reduce its greenhouse gas emissions.

Since the time of its ratification in 1992, the Cambrian GSSP, 23 m above the base of Member 2A (Quaco Road Member) of the Chapel Island Formation, Fortune Head section, Newfoundland, Canada, has been challenged as posing an ambiguous correlation level. Difficulties have been encountered in precisely correlating the horizon coinciding with the GSSP to strata on most paleocontinents, but especially

Epidemiological evidence suggests that the Mediterranean diet (MD) could reduce the risk of breast cancer (BC). As evidence from the prospective studies remains scarce and conflicting, we investigated the association between adherence to the MD and risk of BC among 335,062 women recruited from 1992 to 2000, in ten European countries, and followed for 11 years on average. Adherence to the MD was es

Based on a large data-set, spanning the Ordovician-Early Silurian (Telychian) interval, this study explores the phylogeographic distributional pattern for higher orders of rhynchonelliformean brachiopods through four time slices: Tremadocian, Dapingian-Darriwilian, Katian and Telychian. In addition, a palaeobathymetrical analysis has been conducted for the latter two time slices to assess the phyl

The aim of this article is to elucidate the complexity of internal crisis communication by identifying and discussing different paradoxical tensions embedded within a large, complex, multi-professional organization. This article is based on a qualitative case study of a university hospital. Internal dimensions of crisis management have long been neglected within the field of crisis communication r

We present a platform for micro particle image velocimetry (μPIV), capable of carrying out full-channel, temperature-controlled, long-term-stable, and automated μPIV-measurement of microchannel acoustophoresis with uncertainties below 5% and a spatial resolution in the order of 20 μm. A method to determine optimal μPIV-settings for obtaining high-quality results of the spatially inhomogeneous acou

Evaluation of structure and morphology of extruded wheat gluten (WG) films showedWGprotein assemblies elucidated on a range of length scales from nano (4.4 Å and 9 to 10 Å, up to 70 Å) to micro (10 μm). The presence of NaOH in WG films induced a tetragonal structure with unit cell parameters, a = 51.85 Å and c = 40.65 Å, whereasNH4OHresulted in a bidimensional hexagonal close-packed (HCP) structur

Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP), we genotyped ∼50,000 SNPs in up to 87,736 individuals of European ancestry and combined these in a meta-analysis. We replicated findings in an independent set of 68,368 individuals of Europe

Input data for communication network design/optimization problems involving multi-hour or uncertain traffic can consist of a large set of traffic matrices. These matrices are explicitly considered in problem formulations for link dimensioning. However, many of these matrices are usually dominated by others so only a relatively small subset of matrices would be sufficient to obtain proper link capa

In this paper we propose a new algorithm for solving the Learning With Errors (LWE) problem based on the steps of the famous Blum-Kalai-Wasserman (BKW) algorithm. The new idea is to introduce an additional procedure of mapping subvectors into codewords of a lattice code, thereby increasing the amount of positions that can be cancelled in each BKW step. The procedure introduces an additional noise

Abstract Objectives. Pulmonary hypertension (PH) due to left heart disease may impair outcome after heart transplantation (HT). To evaluate to what extent previous, and present, haemodynamic criteria discriminate the impact of pre-operative-PH on survival, we characterized the PH in our HT-patients according to ESC's guidelines, ISHLT's summary statement and ISHLT's relative contraindications and

Owing to the heterogeneity in the clinical phenotype of haemophilia A and B, it is now recognized that disease severity (based on factor VIII/IX activity) may no longer be the most appropriate guide for treatment and that a 'one-size-fits-all' approach is unlikely to achieve optimal therapy. Based on the present literature and consensus views of a group of experts in the field, this article highli

Two new compounds, [(C4H9)(4)P](2)[Cu5I7], and [(C4H9)(4) P](2)[Cu5I7]center dot CH3COCH2OH were synthesized by solvolysis and their crystal structures were solved. The first compound is disordered, but the solvate represents the first example of a fully ordered [Cu5I7](2-) cluster. It displays a molecular symmetry very close to C-2. Both compounds crystallize in space group P2(1)/c. (C) 2010 Else

Dug trenches in sediment-cored drumlins on the Småland peneplain, southern Sweden, occurring intermixed with rock-cored drumlins, revealed sedimentary successions and facies suggesting that the core sediments were primarily deposited proglacially, both in glaciolacustrine settings as delta-front and more distal deeper-water sediments, and as glaciofluvial braidplain sediments. From the relationshi