Background-Diabetes mellitus (DM) and cardiovascular disease are associated with dyslipidemia, but the detailed lipid molecular pattern in both diseases remains unknown. Methods and Results-We used shotgun mass spectrometry to determine serum levels of 255 molecular lipids in 316 controls, 171 DM, and 99 myocardial infarction (MI) events from a cohort derived from the Malmö Diet and Cancer study.

Colon cancer is the third most common cancer in the world and the fourth most common cause of cancer related deaths. Inflammation is one of the risk factors for development of colon cancer. Interestingly immune cells as mast cells and inflammatory mediators as LTC4 play an important role in colon cancer. Genetic predisposition, which might lead to either activation of oncogenes or inhibition of tu

Within this chapter, we begin with the invaluable context of the experience of living after cancer as a young person. Then we move to describe the growing body of data indicating the consequences of cancer in patients diagnosed aged as teenagers and young adults (YAs). We identify that, while the variation in definitions used in the literature hamper firm conclusions, specific patterns of substant

Gliding flight is a relatively inexpensive mode of flight used by many larger bird species, where potential energy is used to cover the cost of aerodynamic drag. Birds have great flexibility in their flight configuration, allowing them to control their flight speed and glide angle. However, relatively little is known about how this flexibility affects aerodynamic drag. We measured the wake of a ja

Time-series of varve properties and geochemistry were established from varved sediments of Lake Woserin (north-eastern Germany) covering the recent period AD 2010–1923 and the mid-Holocene time-window 6400–4950 varve years before present (vyr BP) using microfacies analyses, x-ray fluorescence (µ-XRF) scanning, microscopic varve chronology, and 14C dating. The microscopic varve chronology was compa

Aim of study: Negotiations about problem definitions are a crucial part of psychotherapeutic and counselling work. In a conversation with a psychotherapist or a counsellor, the client's initial description of his or her trouble is transformed into an expert-informed problem formulation. This study aims to explicate how reasoning about troubles and life difficulties in a dialogue with a psychothera

The activity and adsorption of three variants of human carbonic anhydrase (HCA) with similar topology but variation in charge and stability were studied in the presence of carboxyl-modified polystyrene nanoparticles of different sizes ranging from 25 nm to 114 nm. The balance of forces driving the adsorption of carbonic anhydrase variants is affected by the physicochemical properties of the protei

Abstract:This doctoral thesis is addresses two topics in integrated circuit design: multiband direct conversion cellular receivers for cellular frequencies and beam steering transmitters for millimeter wave communication for the cellular backhaul. The trend towards cellular terminals supporting ever more different frequency bands has resulted in complex radio frontends with a large number of RF in

The evolution of industrial-era warming across the continents and oceans provides a context for future climate change and is important for determining climate sensitivity and the processes that control regional warming. Here we use post-ad 1500 palaeoclimate records to show that sustained industrial-era warming of the tropical oceans first developed during the mid-nineteenth century and was nearly

This thesis, Exports and Externalities consists of three papers. The first chapter, Bridging Trade Barriers: Evaluating Models of Multi-Product Exporters, evaluates empirically the theoretical predictions of several models of multi-product exporters. For identification I use a quasi-natural experiment, the introduction of the Öresund bridge between southern Sweden and Denmark, to analyse the impac

Estrogens are important regulators of bone mass and their effects are mainly mediated via estrogen receptor(ER)α.CentralERα exertsaninhibitoryroleonbonemass.ERα ishighlyexpressedinthearcuate (ARC) and the ventromedial (VMN) nuclei in the hypothalamus. To test whether ERα in proopiomelanocortin (POMC) neurons, located in ARC, is involved in the regulation of bone mass, we used mice lacking ERα expr

Many experiments have shown that loss of biodiversity reduces the capacity of ecosystems to provide the multiple services on which humans depend. However, experiments necessarily simplify the complexity of natural ecosystems and will normally control for other important drivers of ecosystem functioning, such as the environment or land use. In addition, existing studies typically focus on the diver

Thermosensitive Transient Receptor Potential (TRP) channels are believed to respond to either cold or heat. In the case of TRP subtype A1 (TRPA1), there seems to be a species-dependent divergence in temperature sensation as non-mammalian TRPA1 is heat-sensitive whereas mammalian TRPA1 is sensitive to cold. It has been speculated but never experimentally proven that TRPA1 and other temperature-sens

Elektroaktiva polymerers (EAPs) främsta egenskap är deras förmåga att kunna omvandla elektrisk energi till mekanisk energi (och vice versa). Den typ av EAPs som behandlas inom ramen för detta arbete kallas för dielektriska elastomerer och är en undergrupp av elektroniska elektroaktiva polymerer. De karakteriseras av en väldigt låg elastisk styvhet, kapabel till stora elastiska deformationer, och a

The cadastre of King Valdemar is one of the most investigated and debated written sources that survive from early medieval Denmark. In particular, the detailed list of revenue from Halland has attracted a lot of attention. Despite this, many unanswered questions still remain. This article attempts to address some of these queries.

Kalamang is Papuan language spoken by 150 people in the east of Indonesia. The language is threatened with extinction. This thesis treats mainly phonetics and phonology, but also gives an overview over parts of Kalamang grammar. Pronouns, demonstratives, nominal morphology and some basic syntax are discussed, among other things. The thesis also includes a word list with 700 Kalamang lexemes, and a