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Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model

Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in autoradiograms from 6-hydroxydopamine (6-OHDA) rat. In both species, acute levodopa administration was associated with increases in basal ganglia cerebral blood flow (CBF) with concurrent reductions in cerebral metabolic rate (CMR) for glucose in t

A field study of fluorescent and LED classroom lighting

Indoor lighting is facing a massive retrofit to LED lighting. Research is needed to assess whether LED-based lighting can promote energy efficiency, boost visual comfort and support biological functions. This field study considered the lighting of four identical classrooms in an upper secondary school in Helsingborg, Sweden. Two classrooms were fitted with state-of-the-art ceiling pendants contain

Epigenetic markers to further understand insulin resistance

Epigenetic variation in human adipose tissue has been linked to type 2 diabetes and its related risk factors including age and obesity. Insulin resistance, a key risk factor for type 2 diabetes, may also be associated with altered DNA methylation in visceral and subcutaneous adipose tissue. Furthermore, linking epigenetic variation in target tissues to similar changes in blood cells may identify n

Code Generation for Custom Architectures using Constraint Programming

The computation power we expect from the various smart devices we use keeps increasing. Not only do we want faster devices but also less power hungry and energy efficient devices, both for the environment and our personal convenience (remember that "mobile phone" attached to a power plug at all times?).One way of addressing this demand is to build custom processor architectures that focus on a spe

Early adolescents’ motivations to defend victims in school bullying and their perceptions of student–teacher relationships : A self-determination theory approach

The aim of this study was to investigate whether various dimensions of student–teacher relationships were associated with different types of motivation to defend victims in bullying and to determine the association between these types of motivations and various bystander behaviors in bullying situations among early adolescents in Italy. Data were collected from 405 Italian adolescents who complete

Vegetation-climate feedbacks modulate rainfall patterns in Africa under future climate change

Africa has been undergoing significant changes in climate and vegetation in recent decades, and continued changes may be expected over this century. Vegetation cover and composition impose important influences on the regional climate in Africa. Climate-driven changes in vegetation structure and the distribution of forests versus savannah and grassland may feed back to climate via shifts in the sur

Coordination between governance actors in universities : the role of policy documents

This article focuses on coordination between governance actors in a public university. The purpose of this paper is to illustrate and analyze policy documents as governance tools that allow departmental management to coordinate with the authorities, the board, and the management at different university levels. A central finding is that the importance of policy documents as governance tools takes e

Major Intrinsic Proteins - Structure, function, interactions

Denna avhandling behandlar två essentiella ting, vatten som är grundläggande för allt liv på jorden och kväve, vilket är ett grundämne som återfinns i varje protein och DNA. Liksom allt annat, måste dessa ämnen hålla en lagom nivå i cellen. För att klara variationer i tillgänglighet av dessa ämnen, har alla livsformer hittat sätt att påverka upptag och frisättning av dem. För att realisera detta pMajor intrinsic proteins, also referred to as aquaporins (AQPs) are localized in membranes of all domains of life to increase the permeability to water or other small, polar molecules. Several monophyletic groups can be discerned in this large and divergent protein superfamily. Members within these subfamilies commonly show a similar substrate selectivity established by conserved filters. Comparis

The influence of sorption hysteresis on diffusion coefficients represented with different moisture potentials

This paper continues the discussion in a previous paper [Saeidpour and Wadsö doi:10.1016/j.cemconres.2016.02.003] where a clear effect of sorption hysteresis was seen in moisture diffusion coefficients for cement-based materials. Coefficients with vapor content as potential (Dv) had different values depending on whether the sample was in absorption or in desorption. In this paper we recalculate th

Effect of guard cells electroporation on drying kinetics and aroma compounds of Genovese basil (Ocimum basilicum L.) leaves

In this study the effect of the application of pulsed electric fields as pre-treatment before air drying of basil leaves at 50 °C was investigated. The parameters of the electric treatment were designed in such a way that they either (i) electroporated the tissue reversibly (tissue remains viable) and without electroporating the guard cells in the stomata complex (65 pulses of 600 V/cm, 120 μs pul

The impact of liquid preloads varying in macronutrient content on postprandial kinetics of amino acids relative to appetite in healthy adults

The underlying mechanisms for the effect of proteins on appetite regulation, especially in presence of variable macronutrient composition, are not fully elucidated. The present study investigated the absorption kinetics of proteins after co-ingestion with the other macronutrients and examined the impact of circulating amino acids on appetite and satiety-related gut hormones. A randomized, within-s

Urban Cemetery Animals : An Exploration of Animals' Place in the Human Cemetery

This paper investigates the place of animals in the contemporary Swedish human cemetery. It does this by looking at how animals are admitted to cemeteries – alive and dead, above and below ground, physically as well as symbolically. The aim is to shed light on the various ways that animals are experienced and treated in the cemetery, and to explore how this both reflects our changing attitudes to

The effect of a nurse led telephone supportive care programme on patients’ quality of life, received information and health care contacts after oesophageal cancer surgery—A six month RCT-follow-up study

Background Following oesophagectomy, a major surgical procedure, it is known that patients suffer from severely reduced quality of life and have an unmet need for postoperative support. Still, there is a lack of research testing interventions aiming to enhance the patients’ life situation after this surgical procedure. Aim The aim of the study was to evaluate the effect of a nurse led telephone su

Numerical and Symbolic Methods for Dynamic Optimization

Mathematical optimization is becoming increasingly important for engineering in general and control in particular. This thesis deals with numerical methods, primarily direct collocation, and symbolic methods, primarily block-triangular ordering and tearing, for numerical solution of general dynamic optimization problems involving dynamical systems modeled by large-scale differential-algebraic equa