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Impact of Forced Expiratory Volume in 1 Second (FEV1) and 6-Minute Walking Distance at 3, 6, and 12 Months and Annually on Survival and Occurrence of Bronchiolitis Obliterans Syndrome (BOS) After Lung Transplantation

BACKGROUND Development of bronchiolitis obliterans syndrome (BOS) is a great limitation for patient survival in lung transplantation (LTx). A curative treatment for BOS is still missing, and in terminal stages re-transplantation (Re-LTx) is the only salvation. It is possible to slow the progress of BOS if it is detected at an early stage. This might be possible by assessing pulmonary function patt

Two sustainability epistemologies in the marketization of a natural resource

The normative implications of sustainable development mean that different understandings of how sustainability should be achieved will either facilitate or put at risk different values associated with economic, environmental and social aspects of sustainability. By a qualitative analysis of Swedish fishery legislation documents, we analyse and outline the consequences of two different and competin

Linear and non-linear flow mode in Pb–Pb collisions at sNN=2.76 TeV

The second and the third order anisotropic flow, V2 and V3, are mostly determined by the corresponding initial spatial anisotropy coefficients, ε2 and ε3, in the initial density distribution. In addition to their dependence on the same order initial anisotropy coefficient, higher order anisotropic flow, Vn (n>3), can also have a significant contribution from lower order initial anisotro

Monosynaptic retrograde tracing of neurons expressing the G-protein coupled receptor Gpr151 in the mouse brain

GPR151 is a G-protein coupled receptor for which the endogenous ligand remains unknown. In the nervous system of vertebrates, its expression is enriched in specific diencephalic structures, where the highest levels are observed in the habenular area. The habenula has been implicated in a range of different functions including behavioral flexibility, decision making, inhibitory control, and pain pr

Experimental evidence for hybridization of closely related lineages in Plasmodium relictum

Over 50 avian Plasmodium species have been described. However, PCR-based information shows much broader diversity of genetic lineages in these parasites. This discrepancy indicates insufficient knowledge about taxonomic diversity and boundaries of a single species in avian Plasmodium species. In recent taxonomy, most of genetically closely related lineages that share the same morphology and develo

Animal names for Hebrew Bible female prophets

This article explores the literary and ideological dimensions of zoomorphic names for Deborah (bee) and Huldah (weasel)-two of the Hebrew Bible female prophets. The two women stand out among the female protagonists of the Hebrew Bible in three ways: they are the only female prophets endowed with textual legacy, they are remarkably successful in roles usually reserved for men, and they are the only

Immune functions of intestinal dendritic cells

The intestinal surface is daily challenged with tremendous amount of foreign material derived our diet and from the commensal bacteria that densely populate the mucosal surface. Occasionally the gut mucosa is exposed to pathogens trying to enter our body. The important task of the intestinal immune system is to remain tolerant toward innocuous luminal constituents and to elicit defense responses t

Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury

Deposition of amyloid-β (Aβ) is central to Alzheimer's disease (AD) pathogenesis and associated with progressive neurodegeneration in traumatic brain injury (TBI). We analyzed predisposing factors for Aβ deposition including monomeric Aβ40, Aβ42 and Aβ oligomers/protofibrils, Aβ species with pronounced neurotoxic properties, following human TBI. Highly selective ELISAs were used to analyze N-termi