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A new war on nature and people: Taking stock of the Colombian Peace agreement

The Colombian peace agreement officially ended one of the world’s longest internal armed conflicts. But the transformation of land use that takes place in the wake of the peace agreement, has made the historic inequalities of access to land more visible and revealed inherent and violent struggles over resources that persist across the country. In this briefing we analyse the current status of peac

Experience of a systematic approach to care and prevention of fragility fractures in New Zealand

Summary: This narrative review describes efforts to improve the care and prevention of fragility fractures in New Zealand from 2012 to 2022. This includes development of clinical standards and registries to benchmark provision of care, and public awareness campaigns to promote a life-course approach to bone health. Purpose: This review describes the development and implementation of a systematic a

Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

Body fat distribution is a major, heritable risk factor for cardiometabolic disease, independent of overall adiposity. Using exome-sequencing in 618,375 individuals (including 160,058 non-Europeans) from the UK, Sweden and Mexico, we identify 16 genes associated with fat distribution at exome-wide significance. We show 6-fold larger effect for fat-distribution associated rare coding variants compa

Core-shell excitation of isoxazole at the C, N, and O K-edges - an experimental NEXAFS and theoretical TD-DFT study

The near-edge X-ray absorption fine structure (NEXAFS) spectra of the gas-phase isoxazole molecule have been measured by collecting total ion yields at the C, N, and O K-edges. The spectral structures have been interpreted using time-dependent density functional theory (TD-DFT) with the short-range corrected SRC2-BLYP exchange-correlation functional. Experimental and calculated energies of core ex

Biogeographical variation in antimicrobial resistance in rivers is influenced by agriculture and is spread through bacteriophages

Antibiotic resistance is currently an extensive medical challenge worldwide, with global numbers increasing steadily. Recent data have highlighted wastewater treatment plants as a reservoir of resistance genes. The impact of these findings for human health can best be summarized using a One Health concept. However, the molecular mechanisms impacting resistance spread have not been carefully evalua

Education of Refugees

The educational opportunities of refugee learners are shaped by forces of globalization, restrictive mobility regimes and geopolitical agendas, that place them in a position of structural disadvantage. The majority of the world's refugee learners have fled due to armed conflict and reside in neighboring countries in the global South. In many cases forced displacement is protracted, with limited gl

Collaborative housing as a socio-spatial system from a critical realism perspective. Can unintended consequences be understood as causal mechanisms?

Holism, abduction and causality are ways of reasoning that can complement each other to enable better understanding of contemporary wicked problems. Current social challenges include a global housing crisis, unwanted isolation and polarized societies. Systems thinking is instrumental to zoom out a specific phenomenon in an attempt to capture the complexity of reality. It also provides a holistic v

Perceived usefulness of trauma audit filters in urban India : a mixed-methods multicentre Delphi study comparing filters from the WHO and low and middle-income countries

OBJECTIVE: To compare experts' perceived usefulness of audit filters from Ghana, Cameroon, WHO and those locally developed; generate context-appropriate audit filters for trauma care in selected hospitals in urban India; and explore characteristics of audit filters that correlate to perceived usefulness.DESIGN: A mixed-methods approach using a multicentre online Delphi technique.SETTING: Two large

EXPERIMENTAL STUDY ON HEAT TRANSFER ENHANCEMENT OF AIR JET IMPINGEMENT FOR ELECTRONICS THERMAL MANAGEMENT

Jet impingement cooling was investigated on a flat heating surface placed in a flow channel, including single jet cooling, in-line double jet cooling, and combined crossflow and jet cooling; cross-flow cooling was a baseline for comparison. In addition, the in-line double jet cooling was explored with various jet distances. Local Nusselt number distribution was experimentally achieved by the liqui

Extending the Black diagram of bitumen to three dimensions

The ordinary Black diagram of bitumen has only two dimensions. Thus, it does not differentiate the complex shear modulus and phase angle measured under different temperature and frequency conditions. This study proposes to extend the Black diagram to three dimensions by adding a temperature axis. It leads to the combination of multiple necessary ordinary plots in the same three-dimensional (3D) sp

Study on ignition process and flame expansion and propagation characteristics in jet-cooled pilot flameholders using image processing techniques

Wall-type pilot flameholder has been used in aero-engines to effectively create a stable ignition source and achieve an excellent ignition performance in high-velocity flows. The ignition delay, flame propagation, and flame boundary are crucial characteristics to evaluate the performance of pilot flameholders. Previous work displayed the significantly changed ignition performance and flow features

School nurses’ experiences of health-promoting work to prevent stress in Swedish adolescents

Aim: To investigate school nurses’ experiences of health-promoting work to prevent stress in Swedish adolescents. Materials and methods: Swedish school nurses (n = 225) responded to a web survey with open-ended questions. The results were subjected to a qualitative content analysis. Results: Six categories were identified from the analysis: (1) Knowledge of body and soul, (2) Identifying stress an

Insect pest management with sex pheromone precursors from engineered oilseed plants

Pheromones have become an environmentally friendly alternative to conventional insecticides for pest control. Most current pheromone-based pest control products target lepidopteran pests of high-value crops, as today’s manufacturing processes cannot yet produce pheromones at low enough costs to enable their use for lower-value crops, especially commodity crops. Camelina sativa seeds genetically mo

Manufacturing specialized wax esters in plants

Biologically produced wax esters can fulfil different industrial purposes. These functionalities almost drove the sperm whale to extinction from hunting. After the ban on hunting, there is a niche in the global market for biolubricants with properties similar to spermaceti. Wax esters can also serve as a mechanism for producing insect sex pheromone fatty alcohols. Pheromone-based mating disruption