Sökresultat

Filtyp

Din sökning på "*" gav 535696 sökträffar

A cross-sectional study of distress : A cancer response

Aim: To describe the experience of distress in people with cancer of working age. Design: A cross-sectional study. Methods: In this cross-sectional study, patients (N = 168) with both ongoing (N = 56) and completed treatment (N = 105) completed the Distress Thermometer and the detailed problem list. Data were analysed by descriptive and analytical statistics. Results: A large proportion of patient

Numerical study of heat transfer in gravity-driven dense particle flow around a hexagonal tube

In the present paper, the heat transfer of gravity-driven dense particle flow around a hexagonal tube is numerically studied. The velocity vector, time-averaged particle contacting number, particle contacting time and heat transfer coefficient of particle flow are carfully analyzed. Furthermore, the heat transfer performances of particle flow around a hexagonal tube, circular tube and elliptical t

Surveillance of antibiotic resistance in ICUs in southeastern Sweden

Background: A study was designed to assess a computer-based program for continuous registration of antibiotic resistance, statistics concerning severity of illness, and consumption of antibacterial drugs. Methods: The frequency of antibiotic resistance among bacteria in eight ICUs in southeastern Sweden was investigated yearly from 1995 through 1997. The antibiotic consumption in the ICUs was regi

Morphine affects brain activity and volumes in preterms : An observational multi-center study

Objective: We hypothesized that morphine has a depressing effect on early brain activity, assessed using quantitative aEEG/EEG parameter and depressed activity will be associated with brain volumes at term in extremely preterm infants. Study design: 174 preterm infants were enrolled in 3 European tertiary NICUs (mean GA:26 ± 1wks) and monitored during the first 72 h after birth with continuous 2 c

Low antibiotic resistance rates in Staphylococcus aureus, Escherichia coli and Klebsiella spp but not in Enterobacter spp and Pseudomonas aeruginosa : A prospective observational study in 14 Swedish ICUs over a 5-year period

Background: Intensive care units (ICUs) are hot zones for emergence and spread of antibiotic resistance because of frequent invasive procedures, antibiotic usage and transmission of bacteria. We report prospective data on antibiotic use and bacterial resistance from 14 academic and non-academic ICUs, participating in the ICU-STRAMA programme 1999-2003. Methods: The quantity of antibiotics delivere

Detection of Needle Dislodgement Using Extracorporeal Pressure Signals : A Feasibility Study

Venous needle dislodgement (VND) during dialysis is a rarely occurring adverse event, which becomes life-threatening if not handled promptly. Because the standard venous pressure alarm, implemented in most dialysis machines, has low sensitivity, a novel approach using extracted cardiac information to detect needle dislodgement is proposed. Four features are extracted from the arterial and venous p

Short-range remote sensing of water quality by a handheld fluorosensor system

Laser-induced fluorescence is a powerful measurement method for determining the concentration of organic pollutants as well as the amount of algae in water. It can be applied in remote sensing of natural waters and has the advantages of high speed and sensitivity. In this paper, we present a compact handheld fluorosensor system for water quality assessment. The power of the technique is demonstrat

Identification and validation of VEGFR2 kinase as a target of voacangine by a systematic combination of DARTS and MSI

Although natural products are an important source of drugs and drug leads, identification and validation of their target proteins have proven difficult. Here, we report the development of a systematic strategy for target identification and validation employing drug affinity responsive target stability (DARTS) and mass spectrometry imaging (MSI) without modifying or labeling natural compounds. Thro

X-Ray Dark-Field Imaging of Lung Cancer in Mice

Lung cancer accounts for 1.6 million deaths per year worldwide. The majority of patients are diagnosed at advanced stages of the disease and often present with metastasis. Thus, the 5-year survival rate of lung cancer remains around 15%. Early diagnosis of lung cancer allows for better control of the disease with 5-year survival rates up to around 70%. Chest radiography is the most common techniqu

Investigation of Reverse Filament Formation in ITO/HfO2-based RRAM

To overcome the large discrepancy in speed between computational devices and that of contemporary large capacity non-volatile memory (NVM) technologies, resistive random access memory (RRAM) technologies are seen as promising candidates, offering speed/energy improvements in several orders of magnitude while being 3D integration compatible [1]. Indium-Tin-Oxide (ITO) has several unique properties

Assessment of Metal Cutting Tools using Cost Performance Ratio and Tool Life Analyses

Critical raw materials (CRM) are extensively used in tools for metal cutting, such as in cemented carbide tools (cobalt and tungsten), because they provide desired characteristics of high fracture toughness and wear resistance. Both academia and industry are examining CRM-free material alternatives, such as tools based on polycrystalline diamond (PCD) or ceramic materials. These materials are gene

Yttrande över remissen: En ny Riksbankslag (SOU 2019:46)

Lunds universitet har uppmanats att ge synpunkter på rubricerad remiss. Universitetet lämnar här följande kommentarer vilka har utarbetats vid Ekonomihögskolan vid Lunds universitet av docent Fredrik N G Andersson och professor emeritus Lars Jonung. Inflationsmålet infördes för över 25 år sedan. Villkoren för att bedriva penningpolitik har förändrats på ett omvälvande sätt under detta kvartssekel.

Inner ear is a target for insulin signaling and insulin resistance : evidence from mice and auditory HEI-OC1 cells

OBJECTIVE: The mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance on inner ear fluid homeostasis in vivo, and to investigate whether the organ of Corti could be a target tissue for insulin signaling using auditory House Ear Institute-Organ of Corti 1 (HEI-OC1) cells

Effect of In-cylinder Flow Structures on Late Cycle Soot Oxidation in a Quiescent Heavy-duty Diesel Engine

This paper reports on CFD simulations of in-cylinder flow and combustion in an open-bowl heavy duty diesel engine at high load. The focus of the study is to unravel the effect of swirl motion on the soot formation and on the late cycle soot oxidation. To incorporate detailed kinetic mechanism while maintaining a manageable computational time, Representative Interactive Flamelets (RIF) method is em

Concentrated protein solutions investigated using acoustic levitation and small-Angle X-ray scattering

An acoustically levitated droplet has been used to collect synchrotron SAXS data on human serum albumin protein solutions up to a protein concentration of 400mgml-1. A careful selection of experiments allows for fast data collection of a large amount of data, spanning a protein concentration/solvent concentration space with limited sample consumption (down to 3μL per experiment) and few measuremen

Geophysical investigation of glass ‘hotspots’ in glass dumps as potential secondary raw material sources

This study investigates the potential for Electrical Resistivity Tomography (ERT) to detect buried glass ‘hotspots’ in a glass waste dump based on results from an open glass dump investigated initially. This detection potential is vital for excavation and later use of buried materials as secondary resources. After ERT, test pits (TPs) were excavated around suspected glass hotspots and physico-chem