OBJECTIVE: Elevated levels of blood leukocytes have been associated with acute coronary events (CEs), but data on leukocyte subclasses are limited. This study aimed to explore whether blood lymphocyte and neutrophil counts are associated with incidence of CEs and with fatal outcome in subjects who subsequently experienced a first CE. METHODS AND RESULTS: Neutrophil and lymphocyte counts were measu

Om mannen som försökte döda Adolf Hitler 1944, Claus Schenk von Stauffenberg i tysk historieskrivning och amerikansk filmtradition

The increase of obesity and type 2 diabetes on a global scale has increased the interest in how to counteract this epidemic. Improved lifestyle in general is a fundamental approach, but other remedies such as specific weight reduction or diabetes preventive drugs and surgery have also been tested. One problem to understand is what really happens after weight loss. Ongoing studies will try to addre

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Islet autoimmunity in type 1 diabetes results in the loss of the pancreatic β-cells. The consequences of insulin deficiency in the portal vein for liver fat are poorly understood. Under normal conditions, the portal vein provides 75% of the liver blood supply. Recent studies suggest that non-alcoholic fatty liver disease (NAFLD) may be more common in type 1 diabetes than previously thought, and ma

Context: Both leukocyte telomere length and IGF-I are associated with the aging process. A previous in vitro study suggested that IGF-I may modulate telomerase activity in white blood cells, but little is known whether these two systems interact in vivo. Patients and Methods: Leukocyte telomere length was determined using a quantitative PCR assay in 2744 elderly men (mean age 75.5 yr, range 69-81

The aim of the article is to analyse what function quotations have in narrative sequences, argumentative sequences and in conversation. Three aspects of quotations are considered: quotations as constructions, quotation as voices, and quotations as a means of positioning. Examples from Czech and Swedish data illustrate how conversationalists use quotations when they define their own identity and wh

Dialysis patients often suffer from cardiovascular dis- eases, motivating the use of continuous monitoring of car- diac activity in clinical routine. Cardiac pressure pulses propagate through the vascular system and enter the ex- tracorporeal blood circuit of a dialysis machine, where the pulses are captured by pressure sensors. The cardiac pulses are obscured by the much stronger pressure pulses

The F344 rat carries alleles contributing to bone fragility while the GK rat spontaneously develops type-2 diabetes. These characteristics make F344xGK crosses well suited for the identification of genes related to bone size and allow for future investigation on the association with type-2 diabetes. The aim of this study was to identify quantitative trait loci (QTLs) for bone size phenotypes measu