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Measurement of isolated photon production in deep-inelastic scattering at HERA

The production of isolated photons in deep-inelastic scattering ep -> e gamma X is measured with the H1 detector at HERA. The measurement is performed in the kinematic range of negative four-momentum transfer squared 4 < Q(2)< 150 GeV2 and a mass of the hadronic system W-X > 50 GeV. The analysis is based on a total integrated luminosity of 227 pb(-1). The production cross section of isolated photo

Familial Renal Cell Carcinoma from the Swedish Family-Cancer Database

Background: Reliable data on familial risks are important for clinical counselling and cancer genetics. Objective: To evaluate familial risks for renal cell carcinomas (RCC) through parental and sibling probands in the largest available dataset. Design, setting, and participants: This study examined the Swedish Family-Cancer Database on 12.2 million individuals, which contains families with parent

Potent Intratype Neutralizing Activity Distinguishes Human Immunodeficiency Virus Type 2 (HIV-2) from HIV-1

HIV-2 has a lower pathogenicity and transmission rate than HIV-1. Neutralizing antibodies could be contributing to these observations. Here we explored side by side potency and breadth of intratype and intertype neutralizing activity (NAc) in plasma of 20 HIV-1, 20 HIV-2 and 11 dually HIV-1/2 (HIV-D) seropositive individuals from Guinea-Bissau, West Africa. Panels of primary isolates, five HIV-1 a

The Effect of Education on the Assessment of Optic Nerve Head Photographs for the Glaucoma Diagnosis

Background: To evaluate the effect of one lesson of continuing medical education (CME) of subjective assessment of optic nerve head appearance on sensitivity and specificity for the diagnosis of glaucoma. Methods: Ophthalmologists and residents in ophthalmology attending an international glaucoma meeting arranged at Malmo University Hospital, Malmo, Sweden, were asked to grade optic nerve head (ON

Significant conversations and significant networks – exploring the backstage of the teaching arena

This article presents an inquiry into conversations that academic teachers have about teaching. The authors investigated to whom they talk and the forms that these conversations take. The findings indicate that most teachers rely on a small number of significant others for conversations that are characterised by their privacy, by mutual trust and by their intellectual intrigue. Individual teachers

Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery

Background Peripheral arterial disease (PAD) may cause occlusions (blockages) in the main arteries of lower limbs. One treatment option is bypass surgery using autologous (the patient's own tissue) vein graft or prosthetic (artificial) graft. A number of factors influence occlusion rates in these patients, including the material used. To prevent graft occlusion patients are usually treated with an

A search for prompt lepton-jets in pp collisions at root s=7 TeV with the ATLAS detector

We present a search for a light (mass < 2 GeV) boson predicted by Hidden Valley supersymmetric models that decays into a final state consisting of collimated muons or electrons, denoted "lepton-jets". The analysis uses 5 fb(-1) of root s = 7 TeV proton-proton collision data recorded by the ATLAS detector at the Large Hadron Collider to search for the following signatures: single lepton-jets with a

Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence

Background: The secreted enzyme EndoS, an endoglycosidase from Streptococcus pyogenes, hydrolyzes the N-linked glycan of the constant region of immunoglobulin G (IgG) heavy chain and renders the antibody unable to interact with Fc receptors and elicit effector functions. In this study we couple targeted allelic replacement mutagenesis and heterologous expression to elucidate the contribution of En

Effects of galectins and antibodies in HIV infection; Novel Assays

The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. An important tool in detecting and studying bnAbs, are neutralization assays. Here we d

Mechanisms of microbial-host interaction during asymptomatic bacteriuria

Popular Abstract in Swedish Mer än hälften av alla kvinnor har haft en urinvägsinfektion. Infektionen uppkommer när bakterier når urinblåsan och börjar växa. Immunförsvaret känner igen bakterierna, reagerar med en inflammation och symptom som sveda, trängningar och smärtor i nedre magtrakten uppstår. Om bakterierna klättrar upp till njurarna sprider sig inflammationen dit och orsakar ryggsmärtor oUrinary tract infections (UTIs) present an interesting and relevant model for studying microbial adaptation. After establishing significant numbers, the bacteria either cause severe disease, or an asymptomatic carrier state resembling the normal flora at other mucosal sites. Patients with asymptomatic bacteriuria (ABU) are protected from re-infection if the strain that they carry outcompetes more

Synthesis and production of polyhydroxyalkanoates by halophiles: current potential and future prospects

Biodegradable materials with plastic or elastomeric properties are in great demand for a variety of applications. Polyhydroxyalkanoates (PHAs), polyesters synthesized by microorganisms, possess such desired features. Industrial production of PHAs is currently achieved using recombinant Escherichia coli. Nevertheless, recent research on halophiles, salt requiring microorganisms, has shown a remarka

Nuclear-modification factor for open-heavy-flavor production at forward rapidity in Cu plus Cu collisions at root s(NN)=200 GeV

Background: Heavy-flavor production in p + p collisions is a good test of perturbative-quantum-chromodynamics (pQCD) calculations. Modification of heavy-flavor production in heavy-ion collisions relative to binary-collision scaling from p + p results, quantified with the nuclear-modification factor (R-AA), provides information on both cold-and hot-nuclear-matter effects. Midrapidity heavy-flavor R

Current population trends mirror forecasted changes in climatic suitability for Swedish breeding birds

Capsule Swedish breeding bird species that are predicted to experience a more suitable climate by 2050 are currently increasing in numbers. Aims To test, for a large set of breeding birds, if recent population trends mirror the changes in predicted climatic suitability across the Swedish distribution range, and to test if considering natal dispersal improves the fit of the predictive models. Metho

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory diseases. Although the role of toll-like receptor 4 (TLR4) in microglia's inflammatory response is fully acknowledged, little is known about endogenous ligands that trigger TLR4 activation. Here, we report that galectin-3 (Gal3) released by microglia acts as an endogenous par

Asymmetric InGaAs/InP MOSFETs With Source/Drain Engineering

We have developed laterally asymmetric In0.53Ga0.47As/InP MOSFETs with different regrown contacts at the source (In0.53Ga0.47As) and the drain (InP). Introducing a wider bandgap material, InP, as the drain electrode, higher voltage gain g(m)/g(d) has been obtained with a reduced output conductance g(d) and improved breakdown voltage V-bd. For L-g = 50 nm, a high oscillation frequency f(max) = 300

Topological variability of collectives and its import for social epistemology

Social epistemology studies knowledge and justified belief acquisition through organized group cooperation. To do this, the way such group cooperation is structured has to be modeled. The obvious way of modeling a group structure is with a directed graph; unfortunately, most types of social cooperation directed at epistemological aims are variably implementable, including in their structural expre