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Induced hypothermia after cardiac arrest

Popular Abstract in Swedish Bakgrund: Nio av tio patienter som läggs in på sjukhus efter hjärtstillestånd utanför sjukhus är medvetslösa och behöver intensivvård. Dödligheten och risken för varaktiga hjärnskador är stor. Förhöjd kroppstemperatur under intensivvården är förenat med sämre överlevnad och hjärnfunktion. Nedkylning har i djurexperimentella och preliminära kliniska studier visat sig varThis thesis is based on studies of the clinical use of induced hypothermia as an intervention to reduce mortality and neurological impairment after cardiac arrest. After the publication of two trials indicating benefit of induced hypothermia, we developed a registry to assess outcome, possible adverse events and conduct of induced hypothermia when this intervention was implemented in a clinical p

Measuring systemic problems in National Innovation Systems. An application to Thailand

The paper contributes to research on innovation systems in general and, in particular, to the current debate on rationales for innovation policy by providing a framework to identify systemic problems in a given system of innovation and test the framework empirically. The data were drawn from the Thai Community Innovation Survey in the period after which a major change in the country's innovation s

Systemic sclerosis. Novel molecular and epidemiological features of disease.

Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu

Integration, heterochrony, and adaptation in pedal digits of syndactylous marsupials

Background: Marsupial syndactyly is a curious morphology of the foot found in all species of diprotodontian and peramelemorph marsupials. It is traditionally defined as a condition in which digits II and III of the foot are bound by skin and are reduced. Past treatments of marsupial syndactyly have not considered the implications of this unique morphology for broader issues of digit development an

Stem and progenitor cells in brain ad breast malignancies

Stem cells have qualities that clearly distinguish them from all other cells. Capabilities like self-renewal, differentiation and migration make them truly powerful. This thesis deals with different aspects of stem/progenitor cells in relation to cancer. Certain types of neural progenitor cells (NPCs) have been shown to possess a potential of tracking glioma cells in the brain. This makes them pot

Onset of main Phanerozoic marine radiation sparked by emerging Mid Ordovician icehouse.

The Great Ordovician Biodiversification Event (GOBE) was the most rapid and sustained increase in marine Phanerozoic biodiversity. What generated this biotic response across Palaeozoic seascapes is a matter of debate; several intrinsic and extrinsic drivers have been suggested. One is Ordovician climate, which in recent years has undergone a paradigm shift from a text-book example of an extended g

A Power-Scalable DCO for Multi-Standard GSM/WCDMA Frequency Synthesizers

A Digitally Controlled Oscillator (DCO) whose power consumption can be reconfigured while maintaining an almost constant phase-noise figure-of-merit (FoM). This is achieved by using either a single-switch-pair or a complementary (i.e., double-switch-pair) oscillator topology, without disturbing the optimized LC tank of the DCO. The optimal power consumption in the complementary (P-N) configuration

Supporting Distance Vector Routing Over Device Discovery Flows in the Pervasive Middleware PalCom

PalCom is a pervasive middleware that enables users to combine services from different devices into assemblies, or usage scenarios. The mechanism of device discovery in PalCom builds an ad-hoc network of interconnected devices while replacing cross-network periodic keep-alive messages with timely forwarded events that notify devices about the discovery and undiscovery of each other. Moreover, the

A study of combined biomass gasification and electrolysis for hydrogen production

An integrated system for the production of hydrogen by gasification of biomass and electrolysis of water has been designed and cost estimated. The electrolyser provides part of the hydrogen product as well as the oxygen required for the oxygen blown gasifier. The production cost was estimated to 39 SEK/kg H-2 at an annual production rate of 15 000 ton, assuming 10% interest rate and an economic li

The dependence of language on consciousness

For we have the experience of ourselves, of that consciousness which we are, and it is on the basis of this experience that all linguistic connotations are assessed, and precisely through it that language comes to have any meaning at all for us.

International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden

Objectives To assess the consultation prevalence of musculoskeletal (MSK) conditions as presented in different healthcare systems, and to determine the feasibility of comparing prevalence figures between nations. Methods The settings were an English regional database (Consultations in Primary Care Archive (CiPCA)) and the Swedish Skane County Health Care Register. Case definitions, data extraction

Preventive home visits and health - experiences among very old people

Background: As more people reach older age, there is a growing interest in improving old person's health, activity, independence and social participation, thereby adding quality to the extended years. Preventive home visits (PHV) programs for old people have received much attention in recent decades. A large body of research shows mixed effects, and argues that a home visit is a complex social pro