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Epitope-restricted 65-kilodalton glutamic acid decarboxylase autoantibodies among new-onset Sardinian type 2 diabetes patients define phenotypes of autoimmune diabetes.

The 65-kDa glutamic acid decarboxylase (GAD65) autoantibodies (GAD65Abs), commonly found in type 1 diabetes mellitus (T1DM) patients, are also found at lower frequencies in type 2 diabetes mellitus (T2DM) patients. GAD65Abs in T1DM patients are epitope specific, in contrast to those found in other GAD65Ab-positive individuals, including T2DM patients. Our aim was to assess whether epitope-specific

High prevalence of Helicobacter Species detected in laboratory mouse strains by multiplex PCR-denaturing gradient gel electrophoresis and pyrosequencing.

Rodent models have been developed to study the pathogenesis of diseases caused by Helicobacter pylori, as well as by other gastric and intestinal Helicobacter spp., but some murine enteric Helicobacter spp. cause hepatobiliary and intestinal tract diseases in specific inbred strains of laboratory mice. To identify these murine Helicobacter spp., we developed an assay based on PCR-denaturing gradie

Polymerization of N,N-dimethylacrylamide in Aerosol OT-water mixtures: from lamellae to segregation

The polymerizable N,N-dimethylacrylamide (DMAA) is added to the lamellar liquid crystalline system formed by the anionic surfactant Aerosol OT and water. Small angle X-ray scattering, gives the same bilayer thickness and hydrophilic group cross-sectional area as without DMAA, and an environment sensitive fluorescent probe indicates that DMAA is likely to be in the water layers between the AOT bila

En resa till naturen på reklamens villkor

Popular Abstract in Swedish Avhandlingen handlar om naturföreställningar i resereklam och bland re-senärer. Syftet var att analysera hur natur framställs i reklambilder för resor, vad reklamens framställning av natur har för betydelse för vad resenärer vill uppleva och upplever i samband med sin resa samt med vilka argument och bilder resenären själv väljer att återskapa upplevelserna av sin resa It is commonly believed that we live in a culture that is increasingly permeated by visual images. One category of images that we encounter everyday in different media, and that constitutes a large and growing part of media content, is advertisements. Advertisements also have a specific purpose and the images represent, make meaning of, and convey sentiments about phenomena. In this dissertation,

Visual influences on vestibular compensation and postural control

Popular Abstract in Swedish Interaktionen mellan syn- och balanssinne för orienterings- och balansförmåga studerades hos friska försökspersoner, alkoholpåverkade friska försökspersoner och personer med en väldefinierad, ensidig vestibulär skada: translabyrintär vestibulär nervavskärning pga vestibularisschwannom. Balansförmåga i stående studerades med posturografi. Visuo-vestibulär orienteringsförThis thesis aimed to investigate visual-vestibular interactions in healthy subjects and in patients with a well defined unilateral vestibular lesion (vestibular schwannoma before and six months after translabyrinthine surgery). Visual information is particularly important for balance control during perturbed stance. The physical act of having the eyes open or closed affects motion strategy in pos

Constraint-Driven Design Space Exploration for Memory-Dominated Embedded Systems

Today, embedded systems often consist of many different processing, communication, and memory units. This makes an embedded system a multiprocessor system. There are usually many possible multiprocessor architectures and therefore we need tool support for fast evaluation of numerous design alternatives. However, there is a lack of this type of tools which is partially caused by the inherent comple

Mode of binding of fibrinogen, fibronectin and iron-binding proteins by animal enterococci

Sixty-two animal enterococci were examined for their binding of bovine fibrinogen, porcine fibronectin, bovine lactoferrin, bovine apotransferrin and human holotransferrin in the particle agglutination assay (PAA). Individual strains expressed binding of selected glycoproteins to various degrees (0, 1, 2, 3), whereas bovine fibrinogen binding of enterococci from goats, rabbits and rodents was the

Puts- och ytskiktsproblem : vetenskap, hypoteser och praktisk erfarenhet

Rapporten behandlar frostsprängning, saltangrepp, vidhäftning, rörelser - sprickbildning samt åldring - och nedbrytning. Mekanismer, materialegenskaper och provningsmetoder redovisas och kommenteras. Kortfattade resonemang kring områdena vattenavvisande ytbehandling, nedbrytning p g a luftföroreningar samt redovisning av materialegenskaper.

Exposure to environmental tobacco smoke in the household and urinary cotinine excretion, heavy metals retention, and lung function

The relationship between urinary levels of cotinine (U-cotinine) and arsenic (U-As), blood levels of cadmium (B-Cd), blood levels of lead (B-Pb), lung function, and questionnaire data on smoking habits were studied in 107 parents and their 46 children (7-10 y of age). There was a statistically significant relationship between the reported amount of tobacco smoked and U-cotinine levels. Nonsmokers

Pheromone mating disruption of the pine sawfly Neodiprion sertifer : is the size of the treated area important?

Few attempts to control forest insects by means of pheromone mating disruption have been reported. The first such experiments with the European pine sawfly, Neodiprion sertifer (Hymenoptera: Diprionidae), resulted in nearly complete trap catch reduction, but no effects on population density or sex ratio were noted. Unmated females lay eggs, which develop into males only. Therefore, if mating disru

Interfacial tensions in microemulsions

We present a theoretical analysis of the interfacial tensions of microemulsions in ternary systems water-oil-nonionic surfactant. For surfactants based on oligo-ethylene oxide head-groups the temperature can be used to tune the properties of the microemulsions. Explicit expressions are derived for the interfacial tension of both droplet and bicontinuous microemulsions. We also discuss the effect o