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Pregnant smokers: Potential for improvement of intervention

Background In many countries, smoking is considered as the most important preventable risk factor for a complicated pregnancy and delivery. However in Denmark, there is no clear picture of pregnant women. The aim was therefore to examine the prevalence, characteristics and registration of maternal smoking and quitting during pregnancy as well as estimate the potential for improvement.Methods This

Evolution of averaged local premixed flame thickness in a turbulent flow

In the combustion literature, contradictory results on the influence of turbulence on the local thickness of a premixed flame can be found and the present paper aims at contributing to reconcile this issue. First, different measures of local flame thickness in a turbulent flow, e.g. area-weighted and unweighted surface-averaged values of (i) |∇c|, i.e., the absolute value of 3D gradient of the com

Integration of a complete downstream process for the automated lab-scale production of a recombinant protein

In this work, an automated downstream process for the purification and formulation of a recombinant protein was integrated at lab scale in a single chromatography unit. The purification chain consists of three bind-and-elute chromatography columns, a flow-through membrane chromatography step, and a final ultrafiltration-diafiltration (UFDF) step to concentrate and formulate the sample. An integrat

Phonetic Methods in Cat Vocalisation Studies: A report from the Meowsic project

In the project Melody in Human–Cat Communication (Meowsic) we are using established phonetic methods to collect, annotate, pre-process and analyse domestic cat–human vocal communication. This article describes these methods, and also presents results of meow vocalisations in four different mental states showing variation in fundamental frequency (f0).

Islet cell and glutamic acid decarboxylase antibodies in hyperthyroid patients : At diagnosis and following treatment

Objectives. To study the frequency of islet cell (ICA) and glutamic acid decarboxylase (GAD-Ab) antibodies in patients with hyperthyroidism of different types at diagnosis before treatment and in the euthyroid state following treatment. Setting. Department of Endocrinology, Malmo University Hospital, Malmo, Sweden. Subjects and design. Blood samples were collected at diagnosis from 129 hyperthyroi

Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer

BACKGROUND: Apalutamide is an inhibitor of the ligand-binding domain of the androgen receptor. Whether the addition of apalutamide to androgen-deprivation therapy (ADT) would prolong radiographic progression-free survival and overall survival as compared with placebo plus ADT among patients with metastatic, castration-sensitive prostate cancer has not been determined.METHODS: In this double-blind,

Dynamic crack tip fields at steady growth and vanishing strain-hardening

Solutions for propagating mode III cracks in elastic perfectly-plastic solids are obtained as the limit solutions for infinitesimal crack tip speed and infinitesimal linear strain-hardening. The solution for a perfectly plastic material by Chitaley and McClintock (1971, J. Mech. Phys. Solids 19, 147) is not obtained. A point above or below the crack plane will experience first a centred-fan slip l