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Aims: To compare long-term changes in healthcare utilization and costs for type 2 diabetes patients before and after insulin initiation, as well as healthcare costs after insulin versus non-insulin anti-diabetic (NIAD) initiation. Methods: Patients newly initiated on insulin (n. =2823) were identified in primary health care records from 84 Swedish primary care centers, between 1999 to 2009. First,

Proximity and power in collaborative innovation projects. Regional Studies. The proximity literature has so far paid little attention to power relations in collaborative innovation projects. This paper draws on contributions from international business to examine if power constellations between collaborators in innovation projects influence the effects of proximity. An analysis of two cases of col

“Collaboration” is generally portrayed as being beneficial to intelligence and operational police work, even if previous collaborative research shows that conflicts are common between authorities who are supposed to cooperate. The present study focuses on how officers collaborate in their day-to-day management of borderguarding, taking into consideration the different social and cultural backgroun“Collaboration” is generally portrayed as being beneficial to intelligence and operational police work, even if previous collaborative research shows that conflicts are common between authorities who are supposed to cooperate. The present study focuses on how officers collaborate in their day-to-day management of border guarding, taking into consideration the different social and cultural backgrou

With the development of new high-power neutron spallation sources --both for scientific application and as neutron production tool for accelerator-driven systems-- the demand for experimentally obtained nuclear data on the residue nuclei production in the target is constantly increasing. In the present work, we examined two lead-bismuth-eutectic targets, irradiated with high-energy protons, concer

Developmental stress can have organizational effects on suites of physiological, morphological, and behavioral characteristics. In lizards, incubation temperature is perhaps the most significant environmental variable affecting embryonic development. Wall lizards (Podarcis muralis) recently introduced by humans from Italy to England experience stressfully cool incubation conditions, which we here

The Historical Database of Scanian Agriculture (HDSA) is a micro-level database over farm production in the most southern Swedish region of Scania (Skåne) based on flexible tithes. It contains over 85,000 farm level observations of both vegetable and animal production for the period 1702 to 1881. Moreover, this information is supplemented by information on the farmer, the farm, on enclosures, natu

Humanitarian organizations (HOs) often base their warehouse locations on individuals' experience and knowledge rather than on decision-support tools. Many HOs run separate supply chains for emergency response and ongoing operations. Based on reviews of humanitarian network design literature combined with an in-depth case study of United Nations High Commissioner for Refugees (UNHCR), this paper pr

Sharp leading edges with a millimeter-scale radius are required for hypersonic vehicles from aerodynamic reasons. However, with the leading edges being so sharp, stagnation regions at wing and tail leading edges suffer a hostile thermal environment. Therefore, a high-temperature heat pipe is considered to be integrated into the structure of the leading edge to reduce the temperature of the stagnat

Changes in climate are likely to induce changes in precipitation characteristics including intensity, frequency, duration and patterns of events. In this paper, we evaluate the performance of multiple regional climate models (RCMs) in the North American Regional Climate Change Assessment Program (NARCCAP) to simulate storm properties including storm duration, inter-storm period, storm intensity, a

Early detection and differential diagnosis of psychogenicnon-epileptic seizures (PNES) and epileptic seizures (ES) is a majorclinical issue in comprehensive epilepsy centers. Using blind conditionswith patients with PNES (N = 10) and ES (N = 31) before diagnosis,we tested the hypotheses that individuals with PNES would exhibitsignificantly greater dissociativity, hypnotizability, absorption, and h

Semiconductor nanowires are a class of materials recently gaining increasing interest for solar cell applications. In this article we review the development of the field with a special focus on the III-V materials due to their potential to reach high power conversion efficiencies. After introducing basic concepts of nanowire synthesis, we discuss important aspects of nanowire design for high power

Motivation: Solubility is one of the fundamental protein properties. It is of great interest because of its relevance to protein expression. Reduced solubility and protein aggregation are also associated with many diseases. Results: We collected from literature the largest experimentally verified solubility affecting amino acid substitution (AAS) dataset and used it to train a predictor called PON