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Model Predictive Control of an Advanced Multiple Cylinder Engine with Partially Premixed Combustion Concept

Partially premixed combustion (PPC) is an advanced combustion concept and powertrain technology, which has a great potential to improve the fuel economy of vehicles. The process of PPC is driven by both chemical kinetics and mixing process, and is, therefore, sensitive to inlet conditions and injection process. This article presents a control-oriented combustion and air-path model of a PPC multicy

Tuning Viscoelasticity with Minor Changes in Speed of Sound in an Ultrasound Phantom Material

The acoustic properties of ultrasound phantom materials have always been important, but with new applications interrogating tissue mechanical properties, viscoelasticity has also become an interesting feature to consider. Along with Young's modulus, the viscous component of tissue is affected by certain diseases and can therefore be used as a biomarker. Furthermore, viscoelasticity varies between

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene in 13q12.2 are among the most common driver events in acute leukemia, leading to increased cell proliferation and survival through activation of the PI3K/AKT, RAS/MAPK and STAT5 signaling pathways. In this study, we examine the pathogenetic impact of somatic hemizygous 13q12.2 microdeletions in B-cell precursor acute lymphoblastic leukemia (B

RIFM fragrance ingredient safety assessment, cinnamyl alcohol, CAS Registry Number 104-54-1

The existing information supports the use of this material as described in this safety assessment. Cinnamyl alcohol was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization, and environmental safety. Data show that cinnamyl alcohol is not genotoxic. Data on read-across analog cinnamaldehyde

Bioarchaeological field analysis of human remains from the mass graves at Phaleron, Greece

In 2016, archaeological excavations undertaken by the Ephorate of Antiquities of West Attica, Piraeus and Islands 3.8 km south-west of Athens, Greece, revealed mass burials of 79 skeletons in three rows. The burials are dated to the 7th century BC. The anthropological field documentation was undertaken by The Swedish Institute of Athens, and followed established bioarchaeological protocols regardi

Effects of Natura 2000 on nontarget bird and butterfly species based on citizen science data

The European Union's Natura 2000 (N2000) is among the largest international networks of protected areas. One of its aims is to secure the status of a predetermined set of (targeted) bird and butterfly species. However, nontarget species may also benefit from N2000. We evaluated how the terrestrial component of this network affects the abundance of nontargeted, more common bird and butterfly specie

Daily Adaptive Proton Therapy : Is it Appropriate to Use Analytical Dose Calculations for Plan Adaption?

Purpose: The accuracy of analytical dose calculations (ADC) and dose uncertainties resulting from anatomical changes are both limiting factors in proton therapy. For the latter, rapid plan adaption is necessary; for the former, Monte Carlo (MC) approaches are increasingly recommended. These, however, are inherently slower than analytical approaches, potentially limiting the ability to rapidly adap

European Task Force on Contact Dermatitis statement on coronavirus 19 disease (COVID-19) outbreak and the risk of adverse cutaneous reactions

Among the basic protective measures against COVID-19, the need to wash hands frequently and in a prolonged way using soap, and to regularly use alcohol-based hand sanitizers is well established for the whole population. Healthcare workers in general, and particularly those involved in the direct care of COVID-19 patients, have to wear personal protective equipment (PPE) daily for many hours and al

A Scheimpflug lidar used to observe insect swarming at a wind turbine

Wind turbines have considerable impact on flying animals, particularly bats, which are sometimes killed in large numbers by the moving rotors. A longstanding question remains why bats are attracted to wind turbines and risk their lives among the moving rotor blades. One hypothesis is that they feed on insects swarming around the turbine towers and another is that they congregate there to court. Th

Disentangling drivers of soil microbial potential enzyme activity across rain regimes : An approach based on the functional trait framework

The functional trait framework provides a powerful corpus of integrated concepts and theories to assess how environmental factors influence ecosystem functioning through community assembly. While common in plant ecology, this approach is under-used in microbial ecology. After an introduction of this framework in the context of microbial ecology and enzymology, we propose an approach 1) to elucidat

Propensity rules and interference effects in laser-Assisted photoionization of helium and neon

We investigate the angle-resolved photoelectron spectra from laser-Assisted photoionization for helium and neon atoms using an ab initio method based on time-dependent surface flux and configuration interaction singles. We find that the shape of the distributions can be interpreted using a propensity rule, an intrinsic difference in the absorption and the emission processes, as well as interferenc

Pre-Term Delivery and Risk of Ischemic Heart Disease in Women

Background: Women who deliver pre-term have been reported to have increased future risks of cardiometabolic disorders. However, their long-term risks of ischemic heart disease (IHD) and whether such risks are due to shared familial factors are unclear. A better understanding of these risks may help improve long-term clinical follow-up and interventions to prevent IHD in women. Objectives: The purp

Assessment of the Representativeness of MODIS Aerosol Optical Depth Products at Different Temporal Scales Using Global AERONET Measurements

Assessments of long-term changes of air quality and global radiative forcing at a large scale heavily rely on satellite aerosol optical depth (AOD) datasets, particularly their temporal binning products. Although some attempts focusing on the validation of long-term satellite AOD have been conducted, there is still a lack of comprehensive quantification and understanding of the representativeness

Re-positive Cases of Nucleic Acid Tests in Discharged Patients With COVID-19 : A Follow-Up Study

Background: The frequent emergence of the re-positive patients with COVID-19 is a potential threat worldwide. This study aimed to describe data from admission to follow-up for patients with COVID-19 and analyze the possible causes for re-positive nucleic acid tests to provide more scientific basis for reducing the numbers of re-positive patients after discharge. Methods: We retrospectively recorde

Development of high-moisture meat analogues with hemp and soy protein using extrusion cooking

The interest in plant-based products is growing in Western countries, mostly due to health and environmental issues that arise from the consumption and production of animal-based food products. Many vegan products today are made from soy, but drawbacks include the challenges of cultivating soy in colder climates such as northern Europe. Therefore, the present study investigates whether industrial

Considerations for the use of gonadotropin-releasing hormone agonists and antagonists in patients with prostate cancer

Prostate cancer is the second most common cause of cancer-related deaths in men, representing a major source of morbidity and mortality. Androgen deprivation therapy is the primary treatment for patients with advanced prostate cancer at disease presentation, which can be achieved either with surgical or chemical castration. The development of gonadotropin-releasing hormone agonists revolutionized