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Adenovirus type 9 was inoculated sc into newborn Wistar/Furth rats, divided into four groups: (1) six male rats, not treated further; (2) 11 male rats, castrated at 4 weeks of age; (3) 12 male rats, castrated at 4 weeks of age and subsequently treated repeatedly with estrogen; and (4) 12 female rats, not treated further. All of the rats in group 3 developed mammary hyperplasia and tumors (fibroade
Background: ACMG/AMP and AMP/ASCO/CAP have released guidelines for variation interpretation, and ESHG for diagnostic sequencing. These guidelines contain recommendations including the use of computational prediction methods. The guidelines per se and the way they are implemented cause some problems. Methods: Logical reasoning based on domain knowledge. Results: According to the guidelines, several
Background: Homograft tissue is an important reconstructive material used in the surgical correction of a variety of congenital heart defects. The aim of this study is to evaluate the long-term outcome of pulmonary artery (PA) branch patches used in the reconstruction of the thoracic aorta in children. Methods: Retrospective review of 124 consecutive pediatric patients undergoing corrective surger
Från början utbildade universiteten kyrkans prästerskap och från 1600-talet även statens ämbetsmän. Den högre utbildningens fält etablerades under 1800-talet. Då skapades en rad institut vars uppgift var att utbilda det framväxande industrisamhällets expertis i teknik, farmaci, ekonomi m.m. Institutens yrkesinriktade utbildningar byggde på den tidens vetenskaper. När instituten och universitet när
Tre digitaliseringsforskare: Dataspårning måste vara transparent och ha nödvändiga ramar för ansvarsutkrävande och nedmontering efteråt.När myndigheter i en kris vill samla in spårningsdata om medborgare måste vi säkerställa nivåerna och omfattningen på ett tydligt och demokratiskt försvarbart sätt.
Ambitious climate policies have distributional consequences. These require countervailing social policies to keep climate targets acceptable for the electorate. This article analyses data from the European Social Survey as to whether attitudes in relation to climate and welfare policies converge or diverge. It distinguishes four types of social-ecological attitudes: ‘Synergy’ or support for both k
Today, semi-conductor nanowires can be grown with very high precision, using epitaxy. This allows for studies of new nanowire-based quantum devices, likely to be part of novel quantum technologies in the future. This thesis concerns nanostructures based on InAs nanowires. More specifically, it concerns the theoretical treatment of two types of nanowire-based structures: InAs/GaSb core-shell (and c
Background: It is known that patients who acquired methicillin-resistant Staphylococcus aureus (MRSA) in hospitals suffer and feel as plague. Moreover, the patient interaction with nurses and physicians is described as frightening. Little is known about patient experiences after having acquired CA-MRSA concerning care and everyday life. Aim: To reveal and interpret otherwise healthy patients’ live
Introduction: The acoustic environment in the intensive care unit patient room, with high sound levels and unpredictable sounds, is known to be poor and stressful. Therefore, the present study had two aims: to investigate staff knowledge concerning noise in the intensive care unit and: to identify staff suggestions for improving the sound environment in the intensive care unit patient room. Method
The influence of car brake system parameters on particulate matter emissions was investigated using a pin-on-disc tribometer. Samples from a low-steel friction material and a cast iron disc were tested for different sliding velocities, nominal contact pressures and frictional powers. Disc temperatures were also measured. Their impact on total concentration, size distribution, particle coefficient
Running-in process of low metallic brake pads and cast iron discs are investigated using full scale inertia brake dynamometer designed for particle emission studies. The airborne particles are measured using ELPI+ and collected on filters. The pads and disc contact surfaces are studied using microscopy techniques. It is observed that the particle emissions from the new pads and discs are significa
Particle emissions originating from the sliding disc brake contact in disc brakes are a main contributor to PM10 in Europe. The macroscopic friction and wear behaviour can be explained, at the mesoscopic scale level, by the growth and destruction of contact plateaus. This paper further develops a cellular automaton that describes the mesoscopic contact situation by implementing friction, wear, and
During braking, both the rotor and the pads are worn in disc brakes. This wear process generates particles which may become airborne. In passenger car field tests it is difficult to distinguish these particles from others in the surrounding environment. It may therefore be preferable to use laboratory test stands and/or simulation models to study the amount of airborne wear particles generated. Th
In this paper, we generalize the one-bit quantized low resolution RELAX algorithm to allow for exponentially decaying modes. The resulting greedy algorithm exploits a time-varying threshold to allow for the estimation of the parameters detailing the modes. The improvement offered by the proposed algorithm as compared to its predecessor, and the corresponding Cramér-Rao Lower Bound, is illustrated
The project “Energy and Society”, sponsored by the Swedish Secretariat for Futures Studies, has studied different indigenous alternatives to imported oil in Sweden. Having no domestic oil, gas or coal, Sweden is 70% dependent on imported oil. This will have to change, either due to resource depletion within the next several decades, or due to oil-rich countries limiting export. Both Nuclear Sweden
We have been investigating populations of cataclysmic variables (CVs) in a set of more than 300 globular cluster (GC) models evolved with themoccacode.[-120pt] One of the main questions we have intended to answer is whether most CVs in GCs are dynamically formed or not. Contrary to what has been argued for a long time, we found that dynamical destruction of primordial CV progenitors is much strong
In this study the effect of irrigation by dam water in Bigherd area (Fars province, Iran) on groundwater quality one and three years after Dam construction was investigated. To conduct this study the major ion concentrations, including HCO3−, Ca2+, Mg2+, Na+, K+, SO42− and Cl−, and water levels in 10 water wells and the dam reservoir were measured during two periods (June 2009 and June 2011), anal
Aim: This study explored the cost consequences of introducing hexaminolevulinate hydrochloride-guided blue-light flexible cystoscopy (HAL BLFC) as an adjunct to white-light flexible cystoscopy compared with white-light flexible cystoscopy alone, for the detection and management of nonmuscle invasive bladder cancer in Sweden. Methods: The model evaluated 231 patients in the outpatient setting after
The aim of the present paper is to investigate the level of airborne wear particles released during the dyno-bench tests with the brake pads consisting of alkali-activated slag as an abrasive. Airborne wear particles are generated with a full-scale dyno-bench adapted for airborne wear particles emission studies. The tested disc brake is equipped with two semi-metallic brake pads and a grey cast ir
