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Streptococcus pyogenes nuclease A interferes with host complement functions

Bacterial pathogens deploy diverse virulence factors to subvert host immunity, yet the molecular details of these interactions often remain unresolved. Here, we investigate the structure and host interactome of the Streptococcus pyogenes nuclease A (SpnA). We characterized the structure and dynamics of SpnA using hydrogen-deuterium exchange mass spectrometry and single-particle electron cryo micro

Entanglement transfer in a composite electron-ion-photon system

We study how entanglement in photoionization is transferred from an electron-ion pair to an electron-photon pair by fluorescence. Time-resolved von Neumann entropies are used to establish how information is shared between the particles. Multipartite entanglement, between electron, ion and photon, is found on intermediate timescales. Finally, it is shown how a phase-locked two-pulse sequence allows

Phygital Curation - Embodied Experiences

This thesis examines users’ responses to immersive art installations and the curatorial challenges of exhibiting such hybrid, “phygital” forms. It asks: How do the virtual worlds created by Danish artist Jakob Kudsk Steensen evoke emotional responses and empathy, shaping users’ understanding of the world? How do exhibition design and curatorial aesthetics influence users’ embodied encounters wit

Documentation of a hydrous ultramafic magma intrusion in the 1.62 ga crust of Southern Sweden

Field relationships and petrology of a mid Proterozoic (1624 ±6 Ma) hornblendite from southwestern Sweden demonstrate that it originated as a mafic-ultramafic hydrous melt. Lobes and veins of hornblendite penetrate the surrounding gneiss and small gneiss xenoliths lie in the main body of the hornblendite, evidence that it intruded with relatively low viscosity. The hornblendite has a composition c

Dramaencyklopedin : En bok om att läsa och skriva dramatik

Vi människor lever genom berättelser, men det är dramat som ställer livet och levandet på sin spets, som får oss att lyssna mer uppmärksamt, minnas viktiga erfarenheter bättre, känna starkare och tänka klarare. Därför dramatiseras nyheter och därför konsumerar vi drama från morgon till kväll på tv, mobil och padda. De flesta av oss har därför rika och varierade erfarenheter av drama och vi har nog

Exploring Systems Approaches to Innovation Management From Second-Order Science in the West and China: System of Systems and TiXi

Despite substantial contextual differences between the West and China, systems approaches have been recognized as essential for addressing complex and dynamic management challenges, particularly within the field of innovation. However, most previous studies are rooted in traditional cybernetics within the framework of first-order science, which is characterized by linear processes and stable eleme

Ion microprobe discovery of archaean and early proterozoic zircon xenocrysts in southwest Sweden

A single zircon grain dated by ion probe with a minimum age of 3432±30 Ma was found in a microgranite dyke, which cuts norite of 916±11 Ma Hakefjorden Complex at Älgön on the Swedish west coast north of Gothenburg. Zircons are a rare accessory mineral in this dyke. They could be classified by morphology as orthocrysts and xenocrysts. Data from four orthocrysts show that the dyke originated between

Using the advantages and avoiding the risks – a public survey about the challenges of online purchases of medicines

Background: Around 95% of all websites selling medicines globally are illegal and contribute to the spread of substandard and falsified medicines. Hence, it is important to identify legal pharmacies when accessing medicines online. During 2022-2024, 250 million prescriptions were legally dispensed in Sweden, and 69% were prescribed in primary care. Pharmacists and general practitioners are key hea

Three phase hollow fiber liquid-phase microextraction combined with HPLC-DAD/MS for simultaneous determination of tamoxifen and clomiphene from human urine, plasma and water samples

In this research, a straightforward and effective preconcentration technique was developed by integrating three-phase hollow fiber liquid-phase microextraction (HF-LPME) with high-performance liquid chromatography equipped with a photodiode array detector and mass spectrometry (HPLC-DAD/MS) for the simultaneous extraction and quantification of trace levels of tamoxifen (Tam) and clomiphene (Clom)

Selection bias of ideas for sustainability-oriented innovation in internal crowdsourcing

Decision biases reinforce firms’ tendency to develop innovations based on narrow economic motivations. Consequently, sustainability-oriented ideas explicitly targeting social and environmental issues are easily discarded in idea selection when trade-offs between economic and sustainability values are faced. Given the so far limited knowledge about how sustainability-oriented ideas are developed an

Re-os Dating of Low-Level Highly Radiogenic (LLHR) Sulfides : the Harnäs Gold Deposit, Southwest Sweden, Records Continental-Scale Tectonic Events

To obtain geologically meaningful and precise results on low-level sulfides that are highly radiogenic, blank corrections that account for the extreme difference in the Os isotope composition of sample and blank are necessary, and the resulting data is best plotted in 187 Re- 187Os space, much like the approach used for molybdenites. We here introduce the acronym LLHR as a means of characterizing

Conventional hearing aid amplification, notch therapy, or increased gain at tinnitus pitch : a randomised controlled multicentre study

Objective: To investigate whether modifying hearing aid gain at the individual’s tinnitus pitch augments tinnitus mitigation from hearing aid amplification. Design: Participants were randomised to receive hearing aids delivering either objectively verified Conventional Amplification (n = 36), Increased Gain at Tinnitus Pitch (n = 36), or eliminated gain at tinnitus pitch, so-called Notch Therapy (

Shadow Area and Degrees of Freedom for Free-Space Communication

The number of degrees of freedom (NDoF) in a communication channel fundamentally limits the number of independent spatial modes available for transmitting and receiving information. Although the NDoF can be computed numerically for specific configurations using singular value decomposition (SVD) of the channel operator, this approach provides limited physical insight. In this paper, we introduce a