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Automated Bone Scan Index as a quantitative imaging biomarker in metastatic castration-resistant prostate cancer patients being treated with enzalutamide.

Having performed analytical validation studies, we are now assessing the clinical utility of the upgraded automated Bone Scan Index (BSI) in metastatic castration-resistant prostate cancer (mCRPC). In the present study, we retrospectively evaluated the discriminatory strength of the automated BSI in predicting overall survival (OS) in mCRPC patients being treated with enzalutamide.

Social Characterology. From the Protestant Ethic, via the Social Ethic, to the Hacker Ethic

Starting out from Max Weber's "The Protestant Ethic" the article focuses on a number of authors – David Riesman, William H. Whyte, Daniel Bell and Pekka Himanen – who have used that book as a reference point in their endeavours to capture the spirit of their time. Key themes in the article are ways of life, the formation of social character and charcterological struggle.

Primary Klebsiella pneumoniae Liver Abscess with Metastatic Spread to Lung and Eye, a North-European Case Report of an Emerging Syndrome.

A syndrome of community acquired liver abscess caused by highly virulent hypermucoviscous, rmpA positive Klebsiella pneumoniae strains occurs with high incidence in Asia. We here report a case complicated by metastatic infection, to our knowledge, the first one described in Northern Europe. This and other recently reported cases indicate the emergence of this severe syndrome outside of Asia.

Are Hypnotic Benzodiazepine Receptor Agonists Teratogenic in Humans?

BACKGROUND:: Hypnotic benzodiazepine receptor agonists (HBRAs; zolpidem, zopiclone, and zaleplon) are used in the treatment of insomnia. Little is known about the safety of HBRAs during pregnancy. METHODS:: Data from the Swedish Medical Birth Registry from July 1, 1995, up to 2007 were used to identify 1318 women who reported the use of HBRAs in early pregnancy. They gave birth to 1341 infants. Ma

Costs associated with sharps injuries in the Swedish health care setting and potential cost savings from needle-stick prevention devices with needle and syringe.

The number and costs associated with reported sharps injuries in Swedish hospitals and the potential cost offset by introducing safety devices with needle and syringe was estimated from a health care perspective. Data about reported sharps injuries were collected from infection control nurses at 18 Swedish hospitals and information about the procedures following such injuries from doctors at Swedi