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Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli.
The intestinal microbiota is vital for shaping the local intestinal environment as well as host immunity and metabolism. At the same time, epidemiological and experimental evidence suggest an important role for parasitic worm infections in maintaining the inflammatory and regulatory balance of the immune system. In line with this, the prevalence of persistent worm infections is inversely correlate
Towards a reflexive study of norms, norm diffusion and identity (re-)construction: The transformative power of the EU in the Western Balkans
The “constructivist turn” in International Relations has enhanced our understanding of the power of ideational phenomena such as ideas, norms and identity in world politics . This turn also paved the way for debates on normative power and norm transfer, which have proved to offer fruitful insights into EU normative power and the EU’s identity as an international actor. Exploring the modes of gover
Heltäckande om viktigaste slaget
Recension av The Gettysburg Museum.
Experimental vitreous tamponade using polyalkylimide hydrogel
To evaluate polyalkylimide as a possible vitreous tamponading agent. A 20-gauge pars plana vitrectomy and posterior vitreous detachment were performed in the right eye of six pigmented rabbits. Approximately 1 ml of viscoelastic gel, polyalkylimide (Bio-AlcamidA (R)) was thereafter injected into the vitreous space. Full-field ERG and intraocular pressure (IOP, Tonopen) was measured pre-and postope
Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping
What conformations do protein molecules populate in solution? Crystallography provides a high-resolution description of protein structure in the crystal environment, while NMR describes structure in solution but using less data. NMR structures display more variability, but is this because crystal contacts are absent or because of fewer data constraints? Here we report unexpected insight into this
Candelaria pacifica sp. nova (Ascomycota, Candelariales) and the identity of Candelaria vulgaris.
Candelaria pacifica is formally described. It is currently known from North and South America and Europe. The species is characterized by a small, lobate thallus with soredia formed on the lobe tips and along the margins. It has been confused with C. concolor in Europe and North America, but differs in having 8-spored asci and in lacking a lower cortex. Candelaria vulgaris, the type species of the
Characterization of Indigestible Carbohydrates in Various Fractions from Wheat Processing
Fractions rich in indigestible carbohydrates, such as fructan and arabinoxylan, are obtained as by-products when ethanol, starch, and gluten are produced from wheat flour. Today, these fractions are used as animal feed. However, these components may have positive physiological effects in humans. In this study, the content of indigestible carbohydrates in distillers' grains and process streams from
Trestenshult och den tidiga småländska glashanteringen
Comparative Study of Teaching Computational Mathematics in Two Different Learning Environments
Popular Abstract in Swedish I denna avhandling undersöker vi vilka anpassningar som behöver göras i designen av matematikkurser när de överförs från en kulturell miljö till en annan. Vi fokuserar på en kurs i beräkningsmatematik som undervisas på Lunds Universitet i Sverige och som vi under studien överförde till Sorans Universitet i Kurdistan/Irak. Projektet har två delar. Den första diskuterar hThis thesis aims to investigate necessary adaptations in the design of a mathematics course when it is transferred from one cultural environment to another. We focus on an elementary course in computational mathematics with Python taught at Lund University, Sweden, and at Soran University, Kurdistan/Iraq. This project holds two main parts. The first part elucidates how the necessary changes in tea
Christianity and Cormac McCarthy's The Road
Cormac McCarthy's The Road takes place not before or during but after the end. The novel follows a man and his son as they seek to survive in what remains of the world after some unspecified cataclysmic event. There is almost nothing left: no society, no food, no animals, no hope. Many readers will feel that the question the novel poses is why anyone would wish to continue living under such circum
Amplitudes, rates, periodicities and causes of temperature variations in the past 2485 years and future trends over the central-eastern Tibetan Plateau
Amplitudes, rates, periodicities, causes and future trends of temperature variations based on tree rings for the past 2485 years on the central-eastern Tibetan Plateau were analyzed. The results showed that extreme climatic events on the Plateau, such as the Medieval Warm Period, Little Ice Age and 20th Century Warming appeared synchronously with those in other places worldwide. The largest amplit
Road Traffic Noise - Factors modifying its relation to annoyance and cardiovascular disease
Popular Abstract in Swedish Minst en miljon friska levnadsår går förlorade varje år på grund av trafikbuller i Västeuropa. Buller stör vardagsaktiviteter och sömn, samt har kopplats samman med flera andra dåliga effekter på livskvalitet och hälsa, bland annat ökad risk för högt blodtryck och hjärtinfarkt. Vi vet från tidigare forskning att de dåliga effekterna av trafikbuller kan ändras av socialaTraffic noise causes annoyance and sleep disturbance and has been linked with several other adverse effects on life quality and health, including increased risk of hypertension and myocardial infarction. Conservative estimates assume that at least one million healthy life years are lost every year from traffic related noise in the western part of Europe. We know from earlier studies that the adver
Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9.
Functional studies of resident microglia require molecular tools for their genetic manipulation. Here we show that microRNA-9-regulated lentiviral vectors can be used for the targeted genetic modification of resident microglia in the rodent brain. Using transgenic reporter mice, we demonstrate that murine microglia lack microRNA-9 activity, whereas most other cells in the brain express microRNA-9.
An association between Type 2 diabetes and alpha(1)-antitrypsin deficiency
Aims alpha(1)-Antitrypsin (AAT) is a serine protease inhibitor which recently has been shown to prevent Type 1 diabetes development, to prolong islet allograft survival and to inhibit pancreatic B-cell apoptosis in vivo. It has also been reported that Type 1 diabetic patients have significantly lower plasma concentrations of AAT, suggesting the potential role of AAT in the pathogenesis of Type 1 d
Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study
Background: Exposure to ambient air particulate matter (PM) has been linked to decline in pulmonary function and cardiovascular events possibly through inflammation. Little is known about individual exposure to ultrafine particles (UFP) inside and outside modern homes and associated health-related effects. Methods: Associations between vascular and lung function, inflammation markers and exposure
The General Definition of the Complex Monge-Ampere Operator on Compact Kahler Manifolds
We introduce a wide subclass F(X, w) of quasi-plurisubharmonic functions in a compact Kahler manifold, on which the complex Monge-Ampere operator is well defined and the convergence theorem is valid. We also prove that F(X, w) is a convex cone and includes all quasi-plurisubharmonic functions that are in the Cegrell class.
Exceptional rainfall characteristics related to erosion risk in semiarid Tunisia
The Tunisian Dorsal area is representative of the semiarid Mediterranean region in terms of water resources availability as well as exceptional rainfall characteristics, runoff generation, and soil loss risk. In this context, soil properties, surface management practices together with highly intensive rainfall make the soils vulnerable to erosion. If the exceptional rainfall characteristics are li
The multiple market-exposure of waste management companies: A case study of two Swedish municipally owned companies.
This paper describes how the business model of two leading Swedish municipally owned solid waste management companies exposes them to four different but related markets: a political market in which their legitimacy as an organization is determined; a waste-as-material market that determines their access to waste as a process input; a technical market in which these companies choose what waste proc
Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin - diabetes control and potential adverse events
Inhibition of dipeptidyl peptidase-4 (DPP-4) is a novel oral treatment for type 2 diabetes. DPP-4 inhibition increases insulin secretion and reduces glucagon secretion by preventing the inactivation of glucagon-like peptide-1 (GLP-1), thereby lowering glucose levels. Several DPP-4 inhibitors are in clinical development; more studies exist for sitagliptin and vildagliptin. They improve metabolic co